We report a case of fibrous hamartoma of infancy in a 7-month-old male infant, in which a solitary, asymptomatic, walnut-sized, nomal skin-colored plaque occurred on the left middle back for about one month. Histopathologic findings showed the distinctive features of fibrous hamartoma of infancy, ie, trabeculae of dense collagenous tissue, whorls of immature spindle cells within a mucoid matrix, and interspersed mature adipose tissue, in the lower dermis. The lesion was excised without recurrence.