1) 1978년 10월부터 12월까지 세브란스병원 동위원소실에 내원하여 간 주사상 이상 소견이 있었고 후에 간질환이 확진된 58명의 환자의 질환별 분포는 간경화가 19명, 간암이 18명, 만성 활동성 간염이 7명, 급성 바이러스성 간염이 5명, 간농양이 3명, 폐쇄성 황달이 3명, 기타 외상성 간혈종, 횡경막 하농양과 간디스토마증이 각기 1례였다. 2) 질환별 CEA가의 증가는 다음과 같다. 간경변 19례증 13례(68.4%), 간암 18례중 5례(27.8%), 만성 활동성 간염 7례중 5례(71.4%), 급성 바이러스성 간염 3례중 1례(20%), 간농양 3례 전례(100%), 폐쇄성 황달 3례중 2례(66.7%), 기타 외상성 간혈종, 횡경막하 농양 간디스토마증은 모두 정상가를 보여 주었다. 3) 간경변 환자 19명을 대상으로 한 간 기능검사인 Bilirubin, Alkaline Phosphatase SGOT, Prothrombin time과 CEA가의 관계는 직선상관관계가 없었다.

Carcinoembryonic antigen was initially known as tumor specific antigen and had a potential diagnostic value in the detection of digestive tract malignancies. However, subsequent studies showed CEA and CEA-like antigen present inbenign disease, particul1ary in liver. We had collected sera from 58 patients who had liver scan and later were diagnosed clinically and histologically as liver disease. We estimated CEA values and correlations were made with liver function tests in liver cirrhosis cases. The results: 1) The raised plasma carcinoembryonic antigen level were found in 13 (68.4%) of 19 patients cirrhosis, 5(27.8%) of 18 patients in hepatoma, 5(71%) of 7 patients in chronic active hepatitis, all 3 patients in liver abscesses, 2(66.7%) of 3 patients in liver ablscesses, 2(66.7%) of 3 patients in obstructive biliary disease and none in each one patient of traumatic liver hematoma, subphrenic abscess and clonorchiasis. 2) There is no linear correlation between carcinoembryodic antigen leveland liver function tests including serum bilirubin, alkaline phosphatase, SGOT and prothrombin time in liver patients.