저자들은 1976년 5월부터 12월까지 국군수도통합병원 동위원소실에 내원한 간질환 환자 77명, 정상인 94명을 대상으로 체외계측법에 의한 198Au-colloid의 혈중소실율 T½의 평균치는 2.7±0.4분이었으며 연령 및 성별에 따른 차이는 없었다. 2) 급성간염, 만성간염, 간경변증의 와위에서의 198Au- colloid 혈중소실율 T½의 평균치는 각각 3.0±0.45, 3.5±0.74, 7.2±3.6분으로서 만성간염과 간경변증에서는 정상대조군에 비하여 유의한 간혈류량 감소를 나타냈다. 3) 정상대조군과 급성간염에서 와위에서 입위로 체위변동시 각각 평균 27.7%, 22.6%의 간혈류량 감소를 보였다.

To evaluate the diagnostic significance of the blood disappearance rate of 198Au-colloid and to evaluate the change of hepatic blood flow during position change from supine to erect, we measured the half time of blood disappearance rate of 198Au-colloid using external counting method in 94 normal persons and in 77 patients with various hepatic diseases. The results obtained were as follows: 1) In normal control, the mean blood disappearance half time of 198Au-colloid in supine position was 2.7±0.4 minutes. There was no significant difference of hepatic blood flow in age and sex. 2) In acute hepatitis, chronic hepatitis and hepatic cirrhosis, the mean blood disappearance half times in supine position were 3.0±0.45, 3.5±0.74, 7.2±3.6 minutes respectively. The hepatic blood flow of the patients with chronic hepatitis and hepatic cirrhosis were significantly decreased than that of normal control. 3) In the normal control and acute hepatitis, the decreaces of the hepatic blood flow during the position change from supine to erect were 27.7% and 22.6% respectively.