개복 수술 및 병리조직학적 검사로 확인된 간외성 폐쇄성황달 환자 19예의 교양 198금 간주사와 혈중제거율치 (T½) 그리고 혈청빌리루빈과 알칼리성 인산효소측정치를 분석검토하여 다음과 같은 결론을 얻었다. 1) 간외성 폐쇄성황달환자 19예중 16예 즉 84%에서 간주사 사진상에 간문부위에 특이한 분지상결손상을 볼 수 있었다. 2) 간주사에서 간문부에 분지상결손이 나타난 환자에서의 황달지속 기간은 적어도 3주 이상이었으며 그 기간이 길수록 또 생화학적 검사소견이 나쁠수록 결손상 얼룩이는 더욱 뚜렷하게 나타났다. 3) 방사성 198금 혈중제거율치는 74%에서 정상 범위이었고 정상범위보다 연장된 예에서도 6.0분을 넘는 예는 없었다. 이상의 결과를 종합하여 볼 때 간주사 소견에서 간문주위에 특이한 분지상결손상 내지는 얼룩이가 있고 황달이 3주이상 지속되었으며 방사성 198금 혈중제거율이 정상이거나 조금 연장되는 것은 간외폐쇄성황달의 특징으로 믿는다.

The present study has been undertaken to analyze scan manifestation in obstructive jaundice. Scan changes were correlated with the duration of jaundice. In addition, clearance rates of trace dose of colloidal radiogold were assessed in each case. The materials were consisted of 19 cases with surgically and/or histopathlogically verified obstructive jaundice from various causes including common duct stone, empyema of the gall bladder and carcinoma of the pancreas head etc. Blood clearance rates of colloidal 198Au were determined after the injection of 8 uCi by simple geometrical drawing of recorded strip charts. Scan was performed following additional injection of the sam radiogold. In 16 out of 19 cases, the scan rather typical "arborifrom" mottlings around the porta hepatis. The intensity and appearance of such mottlings on the scan was related with the duration of jaundice and level of serum bilirubin and alkaline phosphatase. The blood clearance rates remained to be within normal range in 74 percent of the patients. In the remaining 26 percent, clearance rate ranged between 4.1 and 6 minutes. It is concluded that the association of "arboriform" mottlings and normal or midly delayed clearance rates in the patients with jaundice is characterisic of obstructive change in the biliary system.