Salivary scan and stimulated salivary clearance of Tc-99m-pertechnetate was performed in 11 pateients with Sjogren syndrome (group I), 4 patients with rheumatoid arthritis (group II), 8 patients with non-connective tissue diseases (group III) and 9 normal controls. Stimulated salivary clearances of pertechnetate of normal controls, group II and group III were in normal range (over 16.5 ml/min) and that of patients with Sjogren's syndrome was significantly reduced (11.1 ml/min).