Allele frequencies at microsatellite loci D14S299 and CSR were analysed by polymerase chain reaction from Korean subjects. According to repeat number of microsatellite, nine alleles were identified at D14S299 locus and PCR amplified frabments ranged from 299 to 331 bps in size. The most frequent allele in this study was allele 30 (44.9%) followed by allele 31 (25.4%) and few more alleles. By the results of statistical analysis, the heterozygosity of D14S299 was 0.710, and the polymorphism information content (PIC) and the power of discrimination (POD) were 0.670 and 0.880, respectively. The genotype distribution and allele frequency of D14S299 microsatellite in Korean population were similar to those of Japanese and Chinese populations. Genes involved in cellular stress response (CSR) possess various numbers of dinucleotide (CA) repeats. Frequencies of two most commonly occurring alleles, a2 and a3, were 31.2% and 31.5% respectively. Allele frequencies agreed with the Hardy-Weinberg expectation. The observed heterozygosity was 0.69 and the values of PIC and POD were 0.730 and 0.866, respectively. We found D14S299 and CSR were genetically polymorphic in the Korean population and useful microsatellite markers for forensic practices.