Prior to the advent of modern antimicrobial therapy and in the preinsulin era, infection accounted for much of the mrtlity of diabetes. .Since antibiotics and insulin had been introduced on treatment of diabetes, mortality caused by infection was decreased but as far as morbidity concerened, diabetic patient were susceptible to infeciion of the urinary tract, rspiratory tract and ski, and susceptible to some secies of bacteria such as E, coli, Staphylococcus sp., Enter- cococcus sp. And fungus such as Cendida species and Toru.:opsis species. Those factors influencirg susce- ptibilty to infection are, clnsly related with blood suger level and partly reversible. In order to it is mecessary to diapsosie at appropriat- ed time and perform adequate treatment on infection in te diabetes. Prevent diabetes from suffering from long- terrn morbid state or from losing their lives because of infecton. The authors experienced a case of spontaneus huge abdominal wall abscess of 50 rear old female diabetic patient. Incision and drainage was performed and the patient discharged with no specific problems.