Growth of uterine myoma to huge size after menopause is very unusual especially when postmenopausal pattern is not on hormone replacement therapy. Recently we experienced 6000g of myoma uteri grown after menopause in 59 year old patient who visited emergency room due to vaginal bleeding for 10 days. After diagnostic work-up to rule out malignancy, she underwent exploration and huge uterine myoma was removed by total hysterectomy and bilateral salpingoopphorectomy. This patient is presented here with brief review of related literatures.