이상의 결과로 보아 자궁내막암의 수술에 있어 동결 절편 진단을 시행함으로써 집도의가 골반 및 부대동맥 임파절에 암세포 전이의 고위험 요소를 선별할 수 있도록 하여 치료방침 결정에 중요한 역할을 할 것으로 사료된다.

From January 1991 to December 1996, a comparative analysis was conducted on 45 consecutive patients underwent hysterectomy for FIGO stage I & II endometrial carcinoma to determine the accuracy of intraoperative frozen section (IFS) diagnosis. The IFS diagnosis and the permanent section diagnosis were compared in myometrial invasion, cervical invasion, adnexal involvement, tumor differentiation, and histological types. In IFS diagnosis, deep myometrial invasion, poor histological type, poorly differentiated tumor, cervical invasion, and adnexal involvement were considered as high risk factors for the pelvic and the paraaortic nodal metastasis. The depth of myometrial invasion (superficial 1/2 vs deep 1/2) was accurately determined by IFS diagnosis in 44 of 45 cases (97.8%). The sensitivity was 93.3%, and the specificity was 96.8%. The following tumor characteristics were also accurately determined by frozen section at surgery: histologic types (91.1%), poorly differentiated tumor (95.6%), cervical invasion (91.1%), and adnexal involvement (100%). One case of deep myomerial invasion, four cases of cervical invasion, and two cases of poorly differentiated tumor were underestimated in IFS diagnosis. 15 of 20 patients (75%) were correctly identified by frozen section at surgery as having high risk for pelvic and paraaortic nodal metastasis. We conclude that IFS diagnosis is an important procedure that enables the surgeon to identify the patients at high risk for the pelvic and the paraaortic nodal metastasis.