희발월경을 동반한 불임여성들의 임상적 특징을 알아 보기 위하여 1994년 3월 1일부터 1996년 3월 1일까지 울산대학교 의과대학 서울중앙병원 산부인과 불임상담실을 방문한 환자중 희발월경을 동반한 불임 여성 82명과 대조군으로 정상월경주기를 가진 불임여성 146명을 대상으로 불임유형, 내분비학적 이상소견, 자궁인자 등을 분석하여 다음과 같은 결과를 얻었다. 1. 1차성 불임의 빈도는 희발월경군에서 35.4%, 대조군에서 26.0%로 두 군간에 유의한 차이가 없었다. 2. 형중 LH의 평균치는 희발월경군에서 11.3±11.3mIU/ml, 대조군에서 5.8±6.1mIU/ml로 희발월경군 에서 유의하게 높았다(p

Oligomenorrhea is defined as the menses occurring at intervals of 37 days to 180 days, and it is one of a common menstrual disorders. In this study, the clinical characteristics and hormonal profiles were analyzed in 82 infertile patients with oligomenorrhea. One hundred fourty-six infertile patients with normal menstrual cycles served as a control. There were no differences in an age and a rate of primary infertility between oligomenorrheic and control group. A basal luteinizing hormone(LH) level was signigicantly higher in an oligom- enorrheic gorup, with 11.3±11.3mIU/ml compared with 5.8±6.1mIU/ml in a control group. A basal follicle stimulating hormone(FSH) level was also significantly higher in an oligom- enorrheic group, with 15.0±29.8mIU/ml compared with 10.1±10.7mIU/ml in a control group. The incidence of hyperprolactinemia(HPRL) and polycystic ovarian syndrome(PCOS) were significantly higher in an oligomenorrheic group than in a control group. However, there were no differences in the incidences of hypothyroidism, hyperthyroidism, and ovarian failure between two groups. There were no differences in the incidences of myoma uteri, congenital uterine anomalies, intrauterine adhesion, luteal phase defect and endometritis between two groups. This study suggests that infertile patients with oligomenorrhea comprise a special group in which ovulatory defects associated with endocrine abnormalities such as HPRL and PCOS can be observed frequently.