A case of successful pregnancy and delivery, after in vitro fertilization and embryo transfer(IVF-ET) through gestational surrogate program, in patient with congenital absence of vagina is reported. The patient who was married after vaginoplasty(McIndoe operation) had only rudimentary uterus but normally functioning both ovaries which were confirmed by laparoscopy. Patient`s younger sister was a completely healthy mother of two and willing to act as a surrogate gestational carrier for her sister. GnRH-a(buserelin), estradiol valerate, hMG and hCG were used for synchronization of the reproductive cycles of the two sisters, controlled artificial preparation of the endometrium and IVF-ET. To maintain pregnancy in gestational surrogate carrier woman, exogenous estradiol and progeterone was administered until placental autonomy was established. A girl(2,950g) was delivered at 41 weeks of gestation and is doing well.