PTP는 동양인에서는 매우 드문 증후군으로서, 대부분의 경우 진단이 안되거나 ITP로 잘못 진단하는 경우가 많다. 특히 수혈을 많이하는 산부인과 의사로서 경산부에 수혈했을때 발병 가능성이 있으며 일단 PTP가 의심이 되면 즉시 치료를 시작해야 한다는 사실을 알아야 할 것으로 생각되며, 본 저자들은 경산부에서 발생된 PTP 1례를 경험하였기에 문헌고찰과 함께 보고하는 바이다.

Post-transfusionpurpura(PTP) is believed to be a rare clinical syndrome characterized by the acute occurrence of severe purpura with thrombocytopenia approximately 1 week after blood transfusion. This syndrome occurs predominantly in patients who lack the platelet-specific alloantigen, and has been previously sensitized by prior transfusion or pregnancy. The typical patient is a middle-aged, multiparous white woman. Diagnosis may be suspected by normal clotting studies, bone marrow biopsy showing increased megakaryocytes, and demonstration of a potent antibody reactive against platelets by appropriate serologic tests. Treatment with corticosteroid and platelet transfusion is ineffective. Exchange trasfusion or plasmapheresis has led to improved survival in this disease. Recent reports indicate that IV IgG may become a effective treatment. We exprienced a case of PTP in a multiparous woman received first blood transfusion during Cesarean section. Here we report this case with brief review of literature.