간편한 뇨중 LH surge 측정방법인 Ovu-QUICK self-test는 대개의 경우(84.9%)에서 Day-2와 Day-0사이 첫 양성반응을 보였으나 Ovu-QUICK 첫 양성이 나타나는 시기와 초음파상 배란이 확인된 시각까지의 기간이 비교적 많은 편차(44.36 34.53시간)를 보이고 2례(5.6%)에서 위음성(false negative)을 보였다. 실제 임상에서 배란예측을 위해 이용시 단독사용은 이와 같은 문제가 있어 주의하여 초음파 등 다른 방법과 함께 사용되어야 할 것으로 생각된다.

The importance of the prediction of ovulation is critical in many gynecological occasions including infertility. Currently BBT, cervical mucus changes, serum E2, serum LH, vaginal ultrasonogram(USG) and serum progesterone level are commonly used for the monitoring of ovulation. Ovu-QUICK self-Test for urinary LH surge is simple, fast and easy to use self test for the monitoring of ovulation. In this study vaginal USG, Ovu-QUICK self-test, BBT and serum progesterone were used to define the accuracy and the relationships of Ovu-QUICK Self-Test with other methods in 36(24 spontaneous and 12 clomiphene induced) ovulatory cycles. Ovulation was confirmed in all cycles by midluteal progesterone. Transvaginal USG detected ovulation(reference point, day of ovulation by USG=day 0) in 35/36(97.2%) cycles and one(2.8%) USG negative ovulatory cycle was considered LUF syndrome. Ovu-QUICK Self-Test revealed positive test in 34/36(94.4%) cycles. In other word, in 2 cases the result were false negative. Most of positive tests(28/33 cycles, 84.9%) occured first between day-2 and day 0 but the variation was rather wide particularly in clomiphene induced cycles. No consistent relationship was identified between the urinary LH surge and BBT nadir. In conclusion, Ovu-QUICK Self-Test is convenient and useful method for the prediction of ovulation but it should be used as a complementary to USG because of its variability for the detection of first positive result.