1. 원추생검 결과 CIN Ⅲ로 판명되어 전자궁적출술을 시행한 151예에서 CIN grade Ⅲ의 잔류빈도를 원추생검방법에 따라 분류시, 질확대경조준하 원추생검시 92예중 20예(22.6%)였고, 육안적생검시 59예중 25예(42.4%)이었다(P<0.05). 2. 원추생검후 전자궁적출술을 시행할 때까지의 시간적 간격에 따른 합병증의 빈도를 보면, 48시간이내와 6주이후의 군에서 각기 7.2%와 20.0%로 나머지 군의 48.8%, 50.0%, 47.1%에 비해 의의있게 적었다(P<0.05). 3. 원추생검 조직검사 결과 CIN grade Ⅲ로 판명된 151예중 45예에서 자궁적출술후 CIN grade Ⅲ가 잔류하여 근막외 자궁적출술이 CIN grade Ⅲ의 치료에 적합한 것으로 생각된다.

To assess the efficacy of colposcopy-directed cervical conization(CCC), compared with that of naked-eye conization(NCC), in the management of cervical intraepithelial neoplasia(CIN), 286 patients with punch-biopsy proven CINs who underwent either CCC or NCC from 1985 to 1988 were evaluated. The incidence of residual grade Ⅲ CIN lesions in the specimens from hysterectomies performed in the presence of histologic documentation of CIN Ⅲ in cervical tissues obtained from CCC, and NCC was 22.6(20/92) and 42.4(25/59) percent respectively(P<0.05). Morbidity after post conization hysterectomy was 7.2 and 20.0 percent with the interval between conization and hysterectomy less than 48 hours, and more than 6 weeks respectively; these were significantly lower than 48.8, 50, 57.1 percents noted interval between 48 hours and 6 weeks(P<0.05). The difference in morbidity was not influenced by the type of conization. It can thus be concluded that CCC, compared with NCC, allows a fairly accurate assessment of the CIN lesions, especially in delineating the lesion`s periphery and extension into inner columnar cells aiding in biosping the tissue of optimum size and shape, diminishing the incidence of residual lesions, and that extrafascial hysterectomy apperars to be an appropriate mode of surgery for CIN Ⅲ.