부산 성분도병원 산부인과에 1983년 7월부터 1988년 6월까지 만 5년동안 분만을 한 총 10,268명의 산모중 임신중 고혈압성질환에 이환된 299명의 산모의 임상적 관찰을 한 결과 다음과 같은 결론을 얻었다. 1. 임신중 고혈압성질환의 발생빈도는 2.91%였다. 2. 임신중 고혈압성질환중에서 전자간 경증의 빈도는 43.8%였고, 전자간 중증은 49.5%였으며 자간증은 5.7%, 만성 고혈압성질환의 빈도는 1.0%였다. 3. 환자의 연령은 25∼29세군이 63.2%로 가장 높았고 35세이상은 5.3%였다. 4. 임신중 고혈압성질환의 경산 회수별 발생빈도는 초산부가 81.2%였다. 5. 계절별 발생빈도는 동계에서 31.1%로 가장 높았으나 계절별 큰 차이는 없었다. 6. 가장 발생빈도가 높은 모체 혈액형은 A형이었고, 가장 낮은 모체 혈액형은 AB형이었다. 7. 출생직후 신생아 체중은 2500gm이상이 78.6%였고, 2000gm이하도 9.1%를 나타냈다. 8. 신생아 성별은 남아에서 약간 그 빈도가 높았으나(52.2%: 47.8%) 유의성은 없었다. 9. 평균 임신기간은 37.1주였고 37∼40주사이가 64.5%로 가장 높았다. 10. 분만방식은 질식분만이 59.2%였고, 그중 자연분만이 48.8%였고, 흡입분만이 10.4%였으며, 제왕절개술에 의한 분만은 40.8%였다. 11. 주산기사망율은 1,000분만당 37명이었고, 모성사망율은 0이다. 12. 안저 소견상 정상이 81.6%, K-W Grade I이 8.7%, Grade II가 20.7%였다. 13. 입원시 혈색소치가 12gm이상이 22.7%였고, 임신빈혈의 빈도는 26.8%였으며, 14gm이상은 2.7%였다. 14. 입원시 혈소판치는 20만∼30만/mm/가 68.2%로 가장 높았으며, 10만이하는 0.7%에 불과하였다. 15. 입원시 뇨단백은 2+ 이상이 74.9%를 보였으며, trace는 단 1예도 없었다.

This epidemiologic & clinical study was undertaken for evaluation on 299 cases associated with hypertensive disorders in pregnancy, who were admitted to St.Benedict Hospital from July, 1983 to June, 1988. The detailed results of the reviews were as follow with the brief literatures. 1. The incidence of hypertensive disorders in pregnancy was 2.91% of total deliveries. 2. Using the classification of American committee on Maternal Welfare, the incidence of hypertensive disorders in pregnancy(HDIP) was follows; Preeclampsia, mild: 43.8% Preeclampsia, severe: 49.5% Eclampsia: 5.7% Chronic hypertensive vascular disorders: 1.0% 3. Most prevalent group of maternal age was in the age 25∼29%, its incidence was 63.2%, and the incidence of maternal age above 35 was 5.3%. 4. According to parity, 81.2% of patients with HDIP were primigravida. 5. Among the four seasons, the most prevalent season was winter(31.1%), but a significant difference in seasonal prevalence was not noticed. 6. The most common type of maternal blood group was A. and the least type was AB. 7. 78.6% of newborn infant were measured as 2500gm or above, and 9.1% were below 2000gm. The average fetal weight born in toxemia patient was lower than the normal mother. 8. There was slightly higher male predominance in fetuses from mothers suffered with the HDIP. 9. The average duration of gestation was 37.1 weeks, and the group of geatational age between 37∼40 weeks was the most prevalent group(64.5%). 10. 59.2% of the patient with HDIP were delivered vaginally, 48.8% spontaneously, 10.4% with vacuum extraction. 11. The stillbirth rate was 3.7% per 1000 births, but maternal mortality rate of HDIP was zero. 12. On fundoscopic finding, the frequency of normal finding was 81.6%, K-W grade I 8.7%, and K-W grade II 20.7%. 13. In 22.7% of patients with HDIP, the level of hemoglobin revealed above 12gm%, and incidence of maternal anemia was 26.8%. 14. Most prevalent group of platelet count was 200,000∼ 299,000/mm, 68.2%, but the group less than 100,000 was only 0.7%. 15. The incidence of 2+ or more of urine albumin on admission in HDIP was 74.9%, but this of trace was 0.