1985년 10월 1일부터 1986년 9월30일까지 만 1년동안 전북의대 부속병원 산부인과에 자궁외 임신이 의심된 총 56예중 개복수술후 병리조직검사결과 자궁외 임신으로 확진된 50예에 대 한 뇨와 혈청의 hCG 정량 및 정성분석, 기타 보조진단법 등을 병행실시하여 다음과 같은 결론을 얻었다. 1. 분만에 대한 자궁외임신의 비는 18:1이었다. 2. 기왕력상 인공유산이 64%로 가장 많았으며, 골반내 염증성질환이 34%, 난관불임술이 12%, 난관성형술이 6%였다. 3. 혈청 B-hCG 분포는 114-42,150mIU/ml였고 평균치는 7952.0±1735mIU/ml였다. 4. 자궁외임신의 B-hCG 치를 같은 시기의 정상임신치와 비교시 최종월경일로부터 50일이훙 에는 정상임신치보다 낮은 치를 나타냈다. 5. 난관임신에서 파열군의 평균 B-hCG 치는 8434.9±1502.2mIU/ml였고 미파열군의 평균치는 7262.0±1892.2mIU/ml로 통계학적 의의는 없었다. 6. 혈청 B-hCG 방사면역측정법은 100%에서 양성으로 나타났다. 7. 뇨 임신반응검사의 가음성율은 B-clone이 26%, planosec이 32%였다. 8. 양성율은 더글라스와 천자가 90%, 복부초음파검사가 75%, 복강경검사가 83%였다. 9. 오진율은 10.7%였다. 10. 자궁외임신으로 사망한 경우는 없었다.
During 12 months from October 1,1985 through September 30, 1986, 56 patients suspected of having ectopic pregnancies underwent radionimmunoassay for determination of serum B-subunit of human chorionic gonadotropin and urine pregnancy test (B-clone and Planosec) in addition to conventionally diagnostic procedures in the Department of Obsterics and Gyunecology, School of Medicine, Chonbuk National University Hospital. 50 patients with a histologically proven ectopic pregnancy were revealed and its results were as follows. 1. The ratio of ectpic pregnancies to deliveries was 1 to 18 (5.5%). 2. past histories comprised dilatation and curettage in 32 cases (64%) pelvic inflammatory disease in 17 cases (34%) tubal ligation in 6 cases (12%) and tuboplasty in 3cases (6%). 3. The range of serum B-hCG in 50 ectopic pregnancies was 114 to 42150mIU/ml with a mean of 7952.0±1735.1mIU/ml. 4. Comparing with B-hCG level during early trimester of normal pregnancy all ectopic pregnancies were in below the normal range of the corresponding gestational age after 50 days from last menstrulal period. 5. 21 patients had ruptured tubal ectopic pregnancies with a mean B-hCG levle of 8434.9±1502.2mIU/ml, whereas 27patients with unruptured ectopic pregnancy had a mean B-hCG level of 7262.0±1892.2mIU/ml. 6. Radioimmunoassay for serum B-hCG was positive in all cases of ectopic pregnancy. 7. False negative rate of B-clone and Planosec was 26% and 32 % respectively. 8. Culdocentesis was positive in 90% of 50 ectopic pregnancies , ultrasonogram in 75% and laparoscopy in 83%. 9. The ratio of a mistaken diagnosis was 10.7%. 10. Mortality rate of 50 ectopic pregnancies was zero.