저자들은 1975년 2월부터 1984년 2월까지 서울대학병원 산부인과에 입원하여 한시적 전자궁적출술 및 골반내 임파절적출술 또는 이와 병행하여 보조적 방사선치료를 받았던 자궁경부암 IB기 216례 및 IIA기 141례를 대상으로 하여 다음과 같은 결론을 얻었다 1 자궁경부암 IIA기가 IB기에 비하여 종양직경 4cm이상, 자궁경부 외 1/3 침윤, 임파절 전이 등이 많았으며(P<0 01), 혈관내 침윤 및 암세포의 조직학적 분화정도 등은 유의한 차이가 없었다(P>0 05) 2 종양직경 4cm이상, 자궁경부 외 1/3침윤, 임파절 전이 등은 상호연관관계가 있었다(P<0 01) 3 혈관내 침윤은 자궁경부 외 1/3침윤, 임파절 전이 등과 상호연관관계가 있었다(P<0 01) 4 암세포의 조직학적 분화정도와 종양의 크기, 자궁경부 침윤정도, 임파절 전이, 혈관내 침윤 등과는 유의한 관계가 없었다(P>0 05) 5 질단단에 침윤이 있는 경우에 재발율이 높았다(33 3% VS 13 2%, P<0 05) 6 종양직경 4cm이상, 자궁경부 외 1/3침윤, 임파절 전이 등이 있는 군에서 2년간 무병생존율이 낮았다(P<0 01) 그러나 혈관내 침윤유무, 암세포의 조직학적 분화정도에 따른 2년간 무병생존율의 차이는 유의하지 않았다(P>0 05) 7 자궁경부암 기에 따른 재발율은 유의한 차이가 없었다(P>0 05) 8 고위험군에서의 재발율이 비고위험군보다 높았으나(P<0 01), 기에 따른 차이는 유의하지 않았다(P>0 05) 9 고위험군에서 수술만 시행한 군과 수술후 보조적 방사선치료를 병행하여 시행한 군에서 재발율은 유의한 차이가 없었다(P>0 05) 10 1개의 임파절에 전이가 있었던 군에 비하여 2개이상의 임파절에 전이가 있었던 군에서 재발율이 높았다(P<0 05)

Clinico-pathological analysis was performed to 216 cases of cervical carcinoma stage IB and 141 cases of cervical carcinoma stage IIA treated by means of total hysterectomy and bilateral lymphadenectomy with or without postoperative radiotherapy in the Department of Obstetrics and Gynecology, Seoul National University Hospital, from Feburary 1975 to Feburary 1984 The results were as follows: 1 There was significant difference in tumor size, depth of invasion and lymph node metastasis between cervical carcinoma stage IB and IIA(P<0 01), but no significant difference in vascular invasion and degree of differentiation(P>0 05) 2 There was significant correlation among tumor size, depth of invasion and lymph node metastasis(P<0 01) 3 There was significant difference in depth of invasion and lymph node metastasis between vascular invasion and noninvasion(P<0 01) 4 There was no significant difference in tumor size, depth of invasion, lymph node metastasis and vascular invasion among degrees of differentiation(P>0 05) 5 The recurrence rate was higher in the patients with positive resection margin(P>0 05) 6 The patients who had bulky primary tumor, deep invasion of cervix or lymph node metastasis had a lower 2-year NED(no evidence of diseases) rates(P<0 01), but the patients who had vascular invasion or degree of differentiation revealed no significant difference in 2-year NED rates(P>0 05) 7 There was no significant difference in recurrence rate between cervical carcinoma stage IB and IIA(P>0 05) 8 Recurrence rate was higher in high risk group such as the patients who had bulky primary tumor, deep invasion of cervix, lymph node metastasis, and/or vascular invasion(P<0 01) 9 There was no significant difference in recurrence rate between operation alone and operation plus postoperative radiotherapy in high risk group(P>0 05) 10 There was significant difference in fecurrence rate between patients with one and two or more lymph node metastasis(P<0 05)