본 일신기독병원에서 1973년 1월 1일부터 1984년 12월 31일까지 12년동안 분만한 총 77,485명에서 나타난 무뇌아 임신 137레에서 관찰된 결과는 다음과 같다 1 무뇌아의 발생빈도는 출생아 1,000에 대해서 1 8이다 2 40세 이상의 고령산모에서 무뇌아 발생빈도가 높다 3 출산 횟수와 무뇌아 발생빈도 사이에는 관계가 없다 4 태아의 위치는 안면위와 둔위가 현저히 많은 빈도를 보였다 5 무뇌아는 여아에서 높은 발생 빈도를 나타냈다 6 산과적 합병증으로 양수과다, 견갑난산, 지연분만, 과숙임신이 증가했다 7 무뇌아의 재발률은 1,000분만당 43이다

This report was based on 137 cases of anencephaly among 77,485 total births at Il Sin Christian Hospital during the period between Jan 1, 1973 and Dec 31, 1984 1 The overall incidence of anencephaly was 1 8 per 1000 births 2 The incidence of anencephaly was higher when the maternal age was 40 and over, but there was no relationship between parity and incidence of anencephaly 3 The diagnosis of anencephaly was made during or after delivery in 40% of the cases, almost all of the these patients being emergency admissions In 60% the diagnosis was made during the antenatal period but of these patients 50% were already at or postterm 4 There was a significant increase of face and breech presentation compared to the overall hospital incidence: 19 4% compared to 0 1%(p<0 005) and 12 7% compared to 6 4% respectively 5 There was a reversal of the usual sex ratio of M:F=0 93 to a preponderance of females to give a ratio of M:F=1:1 23 6 These was significant increase in some obstetric complications both during pregnancy and labor or at delivery compared to the overall hospital incidence The complications with an increased incidence were hydramnios 40 2% compared to 0 3%, postmaturity 24 1% compared to 6 6%, prolonged labor 13 9% compared to 4 3% and shoulder dystocia 5 8% compared to 0 1% 7 There was a significant increase in incidence of anencepalic pregnancy 43/1000 deliveries in the next 93 viable pregnancies after the initial anencephalic pregnancy Early diagnosis of anencephaly and termination of pregnancy could be of great benifit to the mother by reducing obstetric complications and psychological stress