1979년 1월 1일부터 1983년 12월 31일까지 본원에 입원하여 분만한 9235명의 산모중에서 VDRL과 TPHA검사로 매독으로 진단된 104명의 임산부 매독환자를 분석하여 다음과같은 결론을 얻었다 1 임산부에서 매독의 유병율은 1 13%였고, 5년간 9235명중 104명에 해당 되었다 2 산과적 과거력으로는 자연유산이 22 8%, 사산이 14%, 조산이 7 03%, 신생아 사망이 5 3%, 전치태반이 1 8%였다 3 VDRL역가와 TPHA와의 비례관계는 없었다 4 37주미만의 출생은 32 32%이며, 37주이상 42주미만의 출생은 53 53%였고, 과숙아 출생율은 14 14%였으며, 이중 미숙아 출생율이 대조군에 비해 높았다 정상 재태기간에서 태어난 신생아의 평균 체중은 2 908㎏으로 대조군보다 가벼웠다 5 임신중 동반되는 질환은 조산이 32 32%, 과숙아 분만이 14 14%, 임신중독증이 9 61%, 전치태반이 4 8%, 횡위가 3 85%, 둔위가 3 85%, 감염이 3 85% 그리고 양수 과다증이 0 96%로 나타났다 6 출생시 선천성매독의 발생율은 55 77%였고, 신생아 사망이 7 69%, 사산이 5 77%, ARDS가 2 88%, 패혈증이 0 96%였으며, 동반되는 선천성 기형은 장폐쇄, gestroschiasis, cleft palate, small mandible 과 pigeon chest 등이 있었다

Among 9235 pregnant women who were admitted and delivered at Wonju Christian Hospital, Yonsei University, from Jan 1970 to Dec 1983 , one hundred four women were diagnosed as syphilis by VDRL and TPHA test One hundred four pregnant women with syphilis and their new born babies were analysed and the following results were obtained 1 The prevalence rate of syphilis in pregnant women was about 1 13%, of 104 women who were seropositive among 9235 women during 5 years 2 In obstetric history, the incidence of spontaneous abortion was 22 8%, stillbirth; 14%, prematurity; 7 03%, neonatal death; 5 3%, and placenta previa; 1 8% 3 The direct proportion between VDRL titer and TPHA was not existed 4 The premature infant incidence in syphilis group was 32 32%, of which incidence was higher than control group, the term infant; 53 53%, and post term infant; 14 14% The mean body weight of the term infant was 2 908 Kg, that was lighter comparing with control group 5 The obstetric combined disease of those women were as the follows; premature; 32 32%, post term pregnancy; 14 14%, toxemia; 0 96%, and infection; 3 85% 6 At birth, the incidence of congenital syphilis was 55 77%, neonatal death; 7 69%, stillbirth; 5 77%, ARDS; 2 88%, and sepsis; 0 96% and the combined anomalies were as the follows; intestinal obstruction, gastroschiasis, cleft palate, small mandible, and pigeon chest