저자는 1982년 9월 1일부터 1983년 4월 30일까지 부산대학교 의과대학 부속병원 산부인과에 입원, 분만한 만삭의 초산부 60명 및 DHA-S를 투여한 초산부 25명을 대상으로 하여 자궁경부 개대 정도를 philpott의 분만도에서 A,B및 C군으로 나누어 관찰하여 다음과 같은 요약을 얻었다. 1. DHA-S산부는 A,B및 C군에 각각 44.48 및 8%로 분포되어 있었으며 이는 대조군의 30,40,30%와 비교하여 분만경과가 빠른 산부가 유의하게 많았다. 2. A군에서 자궁경부 3 cm에서 완전개대까지의 소요시간이 DHA-S산부가 대조산부에 비해 0.84시간이 단축되어 통계적으로 유의하였으며, 이때 이들의 분만진행 과정을 각각 희귀직선 y=2.1352x+1.5975와 y=1.6014x+2.0252로 나타낼 수 있었다. 3. B군에서는 소요시간이 DHA-S산부가 0.87시간이 짧았으며, 이 때 DHA-S산부의 분만진행 과정을 희귀직선으로 표시하면 y=2.2111x-0.5875로 나타났고, 대조산부는 y=1.7705x-0.1873로 나타낸다. 4. A+B군에서는 DHA-S산부가 대조산부에 비하여 0.88시간이 짧았으며, 이들의 분만진행과정으 희귀직선은 DHA-S산부가 y=2.1793x+0.4610, 대조산부가 y=1.7062x+0.9848이었다.

Dehydroepiandrosterone sulfate(DHA-S) has been used for priming the uterine cervix prior to the elective induction of labor. This study was undertaken to evaluate the effectiveness of DHA-S on the dilatation of the uterine cervix during active phase in primigravida. Study group consisted of 25 normal healthy primigravid parturients who were given 100mg of DHA-S intravenously in their early stage of labor and control group consisted of 60 primigravida with uneventful deliveries. Both groups were selected from the patients who were hospitalized for delivery at the Dept.of Obstetrics and Gynecology, Busan National University Hospital from Sept.1.1982 to April 30.1983. Progress of their labor course was evaluated according to the Philpotts partogram, which is to divide the labor course to A, B, and C zone by drawing alert and action line. The results obtained were as follows: 1. Parturients DHA-S injected distributed 11(44%) to A zone, 24(40%) to B zone, and 2(8%) to C zone. However, control parturients differed in their distribution and were 18(30%) in A zone, 24(40%) in B zone, and 18(30%) in C zone. Most of DHA-S injected parturients (92%) were distributed to A+B zone while only 42 parturients(70%) of control ones belonged to A+B zone. 2. The regression line for the labor progress of the study groups in A zone was y=2.1352x+1.5975(r=0.9965, p<0.01) and that of control one in A zone was y=1.6014x+2.0252(r=0.9893, p<0.01). The time needed for full dilatation from 3cm in DHA-S injected parturients who belonged to A zone was 0.83 hour shorter than control ones. 3. The regression line for the labor progress of the study group in B zone was y=2.2111x-0.5875(r=0.9863, p<0.01) and that of control one in B zone was y=1.7705x-0.1873(r=0.9770, p<0.01). Again, the time needed for full dilatation was 0.87 hour shorter. 4. The regression line for the labor progress of the parturients DHA-S injected in both A and B zone was y=2.1793x+0.4610(r=0.9925, p<0.01) and that of control one in A+B zone was y=1.7062x+0.9848(r=0.9848, p<0.01). The time needed for full dilatation from 3cm was 0.88 hour shorter in study group.