1974년 1월 1일부터 1981년 12월 31일까지 만 8년동안 본 성분도병원에서 임신 20주 이후에 분만한 총 분만아 12664예 중 관찰된 선청성기형 76예를 분석하여 다음과 같은 결론을 얻었다. 1. 총 출산아중 선천성 기형아의 발생빈도는 0.6%였고 남아가 여아보다 다소 높은 발생빈도를 나타냈다. 2. 신생아에서 선천성기형 발생빈도는 0.5%였고 사산아중에서 기형아 발생빈도는 6.0% 로서 사산아에서 기형 발생빈도가 신생아에 비해 12배나 높았다. 3. 저 체중아의 선천성 기형아의 발생빈도는 성숙아의 0.4%에 비해 2.5%로 현저히 높은 발생빈도를 나타냈다. 4. 기형아 분만 산모의 연령 관찰에서 20~24세군이 35세이상군 보다 발생빈도가 높았으며 경산부와 초산부간의 발생빈도는 차이가 없었다. 5.기형아의 선진부위는 두위가 83%, 둔위가 17%로 정상아에 비해 둔위가 월등히 많았으며 분만방법은 질식분만이 79%,제왕절게술분만은 21%이었다. 6. 기형아의 기관별 발생빈도는 중추신경계,소화기계,그리고 근골격계가 각각 26.3%로 높은 빈도를 보였고 비뇨생식기 계통의 발생이 2.6%로 가장 낮은 빈도를 보였다. 7.기형아를 가진 산모중 임신초깅 11.8%에서 약물을 복용하였고 특히 한약을 복용한 예가 6.6%의 빈도를 나타냈다. 8.기형아의 주산기 사망율은 44.7%였고 그중 중추신경계 사망율은 100%로 가장 높았으며, 근골격계 사망율은 10%로 가장 낮은 율을 나타냈다.

This report was based on the 76 cases of congenital anomalies among 12664 newborns delivered after 20 weeks gestastion in Pusan St. Benedict Hospital from Jan. 1, 1974 to Dec.31, 1981. This is clinical study of 76 congenitally malformed babies concerned in the incidence of major congenital anomalies. The analyzed results were as follows. 1. The overall incidences of congenital anomaly were 76 cases(0.6%) among 12664 newborns of total deliveries. The incidence of congenital aomaly in male (0.6%) was higher than that of female(0.4%). 2. The incidence of congenital anomaly in stillbirth was 6.0%, which was 12 folds higher than that of live births(0.5%). 3. The incidence of low-birth weight less than 2500gm in congenital anomaly was 2.5%, which was 6 times higher than that of the non-congenital anomalies (0.4%). 4. The incidence of congenital anomaly was highest in 20~24 maternal age group but, there was no statistic significance among each maternal age groups. 5. The incidence of vertex pressentation in congenital anomaly (83%) was very high compared to breech presentation (17%). In method of deliveries, vaginal deliveries was 79% and cesarean section was 21%. 6. The incidence of the type of congenital anomaly was 26.3% in Central ner- vous system, Digestive system and Musculo-skeletal system and 2.6% in Urogental system respectively. 7. In reviewing the all mothers;past history of delivering babies with one or more occasions of congenital anomilies, 11.8% of all the mothers had history of taking various medicines, especially herb durgs which was 6.6% during the first trimester of pregnancy. 8. The perinatal mortality of congenitally malformed babies was 44.7%, part- icularly it was highest in Central nervous system defect(100%), lowest in musc- ulo-skeletal system(10%).