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난소종양의 임상병리학적 고찰
Clinico-Pathologic Survey on Ovarian Tumors
김재홍(JH Kim),이호근(HK Lee),정기성(KS Chung)
UCI I410-ECN-0102-2009-510-005406398

1969년 1월 1일부터 1980년 6월 30일까지 만 10년 6개월간 고려병원에 입원한 환자중 수술에 의해 제거된 조직표본의 병리조직학적 검사를 통해 난소종양으로 확진된 339예를 조사 대상으로 하여 임상 및 병리학적 고찰을 실시하여 다음과 같은 결론을 얻었다. 1.총 339예중 비종양성 난소낭이 152예 (44.8%), 양성종양이 168예 (49.6%), 악성종양이 19예(5.6%)였다. 2.비종양성 난소낭을 제외한 전 난소종양중 양성낭성기형종이 87예(46.5%)로 가장 많았고, 장액성 낭선종이 36예(19.3%), 점액성낭선종이 35예(18.8%)순이였다. 3.난소종양의 연령 분포는 4~73세였으며 비종양성난소낭에서는 25~44세, 양성종양에서는 25~39세, 악성종양에서는 40~54세에서 가장 많이 볼 수 있고, 비종양성 난소낭의 평균 연령은 35.85세였고, 양성종양은 36.6세, 악성종양은 42.6세였다. 4.비종양성 난소낭을 제외한 난소종양의 주요 임상주소는 북부동통 및 불편감이 72.19%, 복부 종류촉지가 50.27%, 성기출혈 및 불규칙한 월경주기가 36.90%, 복부 팽만감이 8.33%, 아무런 자각 증상을 느끼지 못한 예가 7.14%였다. 5.난소종양의 평균 크기는 비종양성 난소낭의 경우 5.77cm, 양성종양의 경우 9.40cm, 악성종양의 경우 15.0cm였다. 6.복수의 빈도는 비종양성을 제외한 양성종양의 경우 1.80%, 악성종양의 경우 31.58%였다. 7.난소종양의 양측성은 양성종양이 14.88%, 악성종양이 57.89%였다. 8.양성종양에서 월경이 규칙적이었던 예는 60%였고, 불규칙적이었던 에는 28%였으며, 무월경이었던 예는 12%였으며, 악성종양에서는 규칙적이었던 예는 48%였고, 불규칙적이었던 예는 26%였고, 무월경이었던 예는 26%였다. 9.양성종양과 동반된 다른 병소로서는 만성 자궁경부염이 11.9%, 자궁근종이 6.5%, 자궁선 근종이 4.1%의 순이었다. 10.비종양성 난소낭을 동반한 부인과적 수술적응증으로는 자궁근종이 28.9%, 자궁외 임신이 14.5%의 순이었고, 난소낭종 진단하에 개복수술후 조직학적으로 비종양성 난소낭으로 진단된 것이 17.1%였다.

Climico-pathologic studies were made on a series of 339 cases of non-neoplastic and neoplastic ovarian tumors, that were admitted to the Department of Obstetrics and Gynecology, Korea General Hospital during the period of about 10 1/2 years from January, 1969 to June, 1980. The results were as follows; 1)Among 339 cases, 152 cases ( 44.8%) were non-neoplastic and 168 cases (49.6%) were benign and 19 cases ( 5.6%) were malignant ovarian tumors. 2)Among the benign ovarian tumors, cystic teratomas (87 cases, 46.5%) ranked first, followed by serous cystadenoma (36 cases, 19.3%) and mucinous cyst adenoma (35 cases, 18.8%) in order of frequency. 3)The range of age of patient with ovarian tumor was from 4 year-old age to 73 year-old age, mean age of patient with non-neoplastic ovarian cyst was 35.85 years and benign ovarian tumors was 36.6 years and malignant one was 42.6 years. 4)The chief complaints of patients were abdominal pain and discomfort ( 72.1%), abdominal palpeble mass (50.27%), vaginal bleeding and irregular menstruation (36.9%) and abdominal distension(8.33%). 5)Mea diameter was 5.77cm in non-neoplastic ovarian cysts and 9.40cm in benign ovarian tumors and 15.0cm in malignant ovarian tumors. 6)The frequency of ascites was 1.80% in benign ovarian tumors and 31.58% in malignant ovarian tumors. 7)Bilaterality was 14.88% in benign ovarian tumors and 57.89% in malignant ovarian tumors. 8)In benign ovarian tumorm, regular menstruation was 60% and irregular menstruation was 28% and amenorrhea was 12%. In malignant tumor, regular menstruation was 48%, irregular menstruation was 26% and amonorrhea was 26%. 9)Benign ovarian tumor associated with chronic cervicitis was about 11.9% and uterine myoma was 6.5% and adenomyosis was 4.1% in order of frequency. 10)Main operative indication in non-neoplastic ovarian cyst were uterine myoma (28.9%), ectopic pregnancy (14.5%) in order of frequency. Under the impression of ovarian cyst, when exploratory laparotomy was performed, the non-neoplastic ovarian cyst was found in 17.1% of patients.

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