1976년 1월에서 1979년 12월까지 본원 산부인과 세포유전학 연구실에서 시행된 401예의 산전태아염색체검사 중에서 2예의 Down`s Syndrome, 1예의 XYY Syndrome과 1예의 46, XO, 1 marker/47, XO, 2 marker를 진단하였기에 산전태아진단의 필요성을 문헌 고찰과 더불어 논의하였다.

From January 1976 to December 1979, 401 amniotic fluid were studied. Among 401 chromosome analysis of cultured amniotic cells, a 21 trisormy, a D/G translocation, a 47, XYY and a mosaicism of 46, XO, +1 marker/47, XO, 2 markers were detected. All of them were detected from young mother aging 28 to 32 which may suggest that the necessity of routine prenatal diagnosis on pregnant women if there is nearly no complication of amniocentesis on its pregnancy and infant.