저자는 혈청 Seromucoid양의 임신중의 변화와 이의 측정이 임신에 대하여 어느 정도 진단적 가치가 있는지를 규명하기 위하여 정상여성 66명과 임신부 300명의 혈청 Seromucoid양을 Winzler법으로 측정하여 비교한 결과 다음과 같인 결론을 얻었다. 1. 정상 여성의 혈청 Seromucoid양은 143.5±42.93mg/100ml였고, 임신부에서는 351.8±125.15mg/100ml로서 임신시에 유의한 증가를 하였다(T=130.694, P<0.005). 2. 정상치의 95%는 범위(59.4∼227.6mg/100ml)에 대한 정상 대조군 성적의 예민도는 89.7%였고 임신군의 특이도는 80.3%였다. 3. Seromucoid양은 임신주수와는 유의한 상관관계를 보여주지 않았다. 4. 혈청 Sermucoid는 임신의 진단에 상당한 의의가 있는 것으로 사료된다.

Seromucoid is a kind of protein-carborate cornples normally found in human serum. But the exact nature of it and its normal serum level are not yet fully established. Several investigators noticed significant increase in the serum of pregnant women recently. To estimate the normal level of it and to evaluate the efficacy of it as a diagnostic measure of pregnancy, the author collected 66 normal, non pregnant women as control group and 300 pregnant women as experimental group. Its level was quantitated by Winzler`s method and statistical analysis including sensitivity and specificity test were given to the obtained data. The following results were ensued; 1. Significant increase of seromucoid amount was noted in the pregnancy group comparing to that of the control group(T=130.694, P<0.005). 2. The sensitivity of normal control group to the 95% normal range was 89.7% and specificity of pregnancy group to the 95% normal range was 80.3%. 3. No sinificant correlation was noted between the duration of pregnancy and the level of seromucoid. 4. With above data, it is suspected that the quantitating the seromucoid level is highly meaningful in pregnant women.