산부인과 영역의 개복수술후 장관회복과 이에 대한 PGF2α의 효과를 360예의 대조군과 60예의 PGF2α 투여군을 대상으로 여러 가지 임상적 요인과 수술시간에 따른 각각의 배기시간을 통계적으로 조사 분석하여 다음과 같은 결론을 얻었다. 1. 환자의 연령이 31세 이상, 수술전 금식이 안됐던 경우 및 수술후 진통제(Demerol) 투여량이 201mg 이상이었던 경우에 각각 그 배기시간은 늦어졌다. 2. 마취의 유형과 부수적 충수절제술에 따른 배기시간에는 현저한 변화를 볼 수 없었다. 3. 수술시간이 길어짐에 비례하여 그 배기시간은 늦어졌다. 4. PGF2α 투여군에서 대조군에 비해 어느 경우에나 그 배기시간은 빨랐다. 5. 수술시간이 길어질수록, 수술전 금식상태를 유지했을 경우 PGF2α의 효과는 현저하였다. 6. PGF2α 투여후 부작용으로 구역, 구토가 가장 많았고 기타 설사 및 심한 연동통 순이었다.

Two studies were performed in order to present recovery of bowel function and effects of Prostaglandin F2α after obstetric and gynecological celiotomy. In preliminary study of 360 cases, the gas passing hour was analyzed according to several clinical factors and operation time. In the study group of 60 cases Prostaglandin F2α was administered intravenously and which was compared with previous control group statistically using average gas passing hour after operation. The results were as follows: Control group. 1. The longer operating time, the later gas passing was noted. 2. There was no noticable difference by anesthetic type or incidental appendectomy. 3. Delayed gas passing was noted in post operative sedative administration, Demerol 201mg or more, and unprepared NPO state. PGF2α Administration Group. 1. Gas passing hour was shorten than control group in all occasions. 2. The drug effect was remarkable when the operating time was longer and NPO state was prepared. 3. Side effect was noted such as nausea, vomiting, diarrhea, and severe peristaltic pain.