1) 정상임신부에서 섬유소 용해효소는 비임신부에 비해 임신중에 현저히 증가되나 분만중과 분만후에는 점차적으로 감소한다. 2) 자간증 및 중증 전자간증 환자에서는 플라스미노젠의 전량이 정상임신부에 비해서 임신중, 분만중과 분만후 모두 낮은 수치를 보여주었다. 3) 산후출혈 환자에서는 섬유소 용해효소가 정상분만 산모에 비해서 현저히 낮은 수치 를 보였다. 4) 기능성자궁출혈환자에서는 플라스미노젠의 감소가 현저하였고 2예중 1예에서는 활 성플라스민이 검출되었다. 5) 패혈성 복막염환자에서 섬유소용해효소가 거의 소모되었음을 알 수 있었다.

This experimental study was planned to detect the changes of fibrinolytic system in the obstetric and gynecological patients. In this strdy, ENZO-DIFFUSION, fibrin plate Test was used to examine the 3 components of fibrimolytic system; available plasmin (fibrinolytic potential), active plasmin (fibrinolysin) and total plasminogen (profibrinolysin). The results were as follows; 1) In normal pregnancy, profibrinolysin was markedly increased in alte pregnancy, and then gradually decreased in labor and after delivery. fibrinolysin was not detected and fibrinolytkc potential was normal in level in late pregnancy and labor and after delivery. 2) In pre-eclampsia and eclampsia; Fibrinolytic potential was normal in level and fibrinolysin was not detected in late pregnancy, in labor and after delivery. But profibrinolysin was less than that of normal pregnancy. 3) In patient with postpartum hemorrhage, profibrinolysin was markedly reduced in level compared to normal postpartum woman. But fibrinolytic potential was normal in level and fibrinolysin was not detected. 4) In two patients with dysfunctional uterine bleeding, although fibrinolytic potentkal was normal in level, profibrinogen was markedly decreased in % activtty and in one of these, fibrinolysin was detected. 5) In a patient given radical hysterectomy for carcinoma of cervix, profibrinolysin was reduced and fibrinolysin was detected on the lst postoperative day. 6) In a patient with hyaline degeneration and suppuration of myoma uteri and panperitonitis profibrinolysin could not be detected pre-and postoperatively, and also, fibrinolytic potential was absent.