Lippes loop를 착용한 농촌부인 382명의 암성변화잠재능 및 배란성 월경주기를 가진 128명의 loop착용농촌부인의 질표층세포의 핵농축지수를 연구한 바 그 성적은 아래와 같다. Loop비착용군 6,314명의 papanicolau암세포진의 결과는 음성 6,285(9.54), 의증24(0. 38%), 양성 5명 (0.08%)이었고 Loop착용군 382명의 결과는 음성 38명으로 Loop착용군의 암발생잠재능을 인정할 수 없었다. Loop착용군 128명의 월경주기에 대한 질표층세포 농축지수의 변동은 제1,2,3군에서 순차적인 상승을 하여 제4군에서 정점을 이루었고, 그후 제5,6,7군 순으로 점차 감소함 을 관찰하였고 대조군과의 농축지수변동경향의 차이를 인정할 수 없었다.

Cytological studies were made on the induceability of uterine cancer in 382 women using Lippes loop who lived in rural area and studies of karyopyknotic index on 128 women using Lippes loop who seemed to have ovulatory 28 day menstrual cycle were also carried out. The results summarized were as follows. Pap. results on 6314 women of control group were negative in 6285 or 99.54%, suspicious in 24 or 0.38%, positive in 5 or 0.08% respectively. On the other hand 382 women using Lippes loop showed entirely negative smears. Studies on karyo-pyknotic index in 128 women using Lippes loop showed gradual increment in order of group 1,2,3, and revealed peak value at group 4. thereafter gradual decrement was seen in the order of group 5,6,7. These results were very similar to that of control group. Judging from these results it may be considered that the presence of an Lippes loop does not have any effect both on the ovarian function or estrogen activity and inductin of uterine cancer.