저자들은 1975년 4월 1일부터 1976년 3월 31일까지 가톨릭 의과대학 부속 성모병원, 산부인과에 입원 및 외래를 방문한 철결핍성 빈혈 환자들 중 추적검사가 가능하였던 129명을 무작위하게 두 대상군으로 나누어, 분자량의 크기에 차이가 있는 Iorn-Sorbitol과 Iron-Dextran을 투여하여, 혈액상의 치료개선 소견을 비교관찰 하였던바 다음과 같은 결론을 얻었다. 1.Iron-Sorbitrol 투여군과 혈색소의 개선소견을 보면, 치료전 각각 9.1±0.9g/dl와 9.2±0.9g/dl이던 것이 치료후 4주째 각각 12.8±0.8g/dl 와 12.2±0.7g/dl로서 모두유의하게 증가하였으며(P>0.01), 두 투여군간에 유의차를 인정할 수 있었다(p>0.01) 2.Iron-Sorbitol투여군과 Iron-Dextran 투여군의 Hematocrit개선소견을 보면 치료전 각각29.5 ±3.1%와 30.5±3.3% 이던 것이 치료후 4주째 각각 41.4±2.6%와 39.9±2.2%로서 모두 유의하게 증가하였으며(p0.05). 4.망상적혈구의 증가는 치료 시작후 1주째에 모두 최고치에 달해 각각 6.9±1.3%와 5.7±1.2%를 나타냈으며, 이때 Iron-Sorbitol 투여군이 Iron-Dextran 투여군보다 유의하게 증가 하였다.(P * 논문각주

It has been known that the parenteral therapy of iron is effective in the treatment of iron deficiency anemia For a simple method when the iron preparation administered intramuscularly the degree of correction of anemic state in blood is depend upon the effectiveness in the absorpion of iron. We sampled 129 cases among patients who were possible to follow up. They were hospitalized or visited to the out patient clinic of Obstet. and Gynecol. Dept. for the treatment of anemia. In an analysis of 129 patients undergoing treatment of anemia using Iron-Sorbitol (Sorbirone-50) and Iron-Dextran (Ferridex-50) it is concluded that the patieits with Iron-Sorbitol showed faster in correcting anmia. Anemia is commonly seen in every field of medicine Prophylaxis and treatment are clinically very important in this respect. Especially, in the field of Obsterics and Gynecology level of iron in an acute of chonic nature. It is also commonly experienced in pregnancy deliveries neoplastic disease radiotherapy and post-operative cases transfusion But the recent trend showed careful restrictjon on transfusion which administration is a well known method in the treatment for iron deficiency anemias the delay in absorption and G-I troubles are always present. For the amelioration of the disadvantages the parenteral of infusion of iron was developed and it showed merits over the oral therapy We studied two different group of patients on the basis of studies done by Svard and Lindvall(1961) In an analysis of 129 patients undergoing treatment of anemia using Iron-Sorbitol (Sorbiron-50) and Iron-Dextran (Ferridex-50), it is concluded that the patients with Iron-Sorbitol which is smaller in molecular weight compared with Iron-Dextran showed faster in correcting anemia. And the response of anemia correction was like that of total dose infusion at once.