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임신중 무증후성 세균뇨
Asymptomatic Bacteriuria in Pregnancy
정구윤(KY Chung),김영환(YW Kim),권오석(OS Kwon),김영근(YG Kim)
UCI I410-ECN-0102-2009-510-005356708

저자들은 만삭임부 150예를 대상으로 무증후성세균뇨의 빈도를 조사하고 임상적으로 간편한 screening method의 신뢰도를 확인하였고 이들을 관찰 분석하여 다음과 같은 결론을 얻었다. 1. 150예의 만삭임부중 무증후성세균뇨는 16명(10.6%)이었다. 2. Griess test양성은 16예로써 신뢰도는 81%였다. Griess 가음성은 3예로 19%였고 가양성은 3예(19%)였다. 3. Modified Griess test 양성은 18예로써 신뢰도는 94%였다. Modified Griess test 가음성은 1예 (6%)였고 가양성은 2예(17%)였다. 4. 무증후성세균뇨의 균주는 Escherichia coli가 81%로 제일 많았다. 5. 무증후성세균뇨의 16예의 연령은 24세 내지 34세였고 초산이 10예였으며 혈압은 임신중독증 1 예를 제외한 전부가 정상치였다. 6. 무증후성세균뇨 16예에서 조산은 1예로 6.3%였고 대조군에선 12예로 9%였다. 7. 무증후성세균뇨 16예중 뇨로감염증의 과거력을 가졌던 예는 3예(19%)였고 분만후 3개월내 발 생한 뇨로감염증은 신우염 1예를 포함한 4예로 25%였다. 8. 뇨로감염증을 보인 4예를 제외한 무증후성세균뇨 12예 중 1예는 분만 2개월 후 자연치유 되었 다.

The clinical significance of asymptomatic bacteriuria was in the coincidental complication of pyelonephritis during the course of pregnancy and puerperium and also in the prevention of prematurity and progressive renal damage. We have studied the incidence of asymptomatic bacteriuria of 150 term pregnancies by means of bacterial colony count and screening method such as Griess test and Modified Griess test which is simple and highly reliable. We also studied the asymptomatic bacteriuria related to age, parity, blood pressure, pyelonephritis, prematurity and spontaneous healing. The results were as follow: 1. The incidence of asymptomatic bacteriuria among 150 term pregnancies was 10.6% (16 cases). 2. The positive Griess test was seen in 16 cases and it`s reliability was 81%. Griess false negative was seen in 3 cases (19%) ans false positive was seen in 3 cases (19%). 3. Positive modified Griess test was seen in 18 cases and it`s reliability was 94%. Modified Griess false negative was seen in 1 case (6%) and Modified Griess false positive was seen in 2 cases (17%). 4. The most predominant organism was E. coli. with an incidence of 81%. 5. The age distribution was from 24 to 34. Primiparas were 10 cases among 16 cases. The 16 cases except 1 preeclampsia showed normal range of blood pressure. 6. The incidence of prematurity was 6.3% among the asymptomatic bacteriurics compared with 9% in the control group. 7. 3 cases (19%) revealed past history of urinary tract infection. 4 cases (25%) showed an evidence of urinary tract infection on the 3rd month of postpartum and 1 case of them showed typical pyelonephritis. 8. Spontaneous healing occurred in 1 case on the second month of postpartum.

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