It has been reported earlier that a certain relation exists between the glycogen content of the fetal heart and survival of the fetus under anoxia. The effests of maternal glucose loading on fetal distress were studies in 40 cases of full term pregnancy. One group of 20 cases server as controls without infusion of glucose, and the other study group of 20 cases was given an infusion of 50ml of 50% glucose solution intravenously 1-2 hours before delivery. Following the infusion of glucose solution, changes of fetal heart rates, plasma glucose levels, CO2 and O2 contents in the cord blood and amniotic fluid pH were determined & compared with those of control group. The results were as follows; 1) The umvilical arterial glucose content at birth was lower than that of umbilical venous blood and both arteral & venous glucose levels of the study group were found to be higer than those of control group. 2) In the cases of glucose loaded fetus, fetal heart activity was improved and stabilized. In the bradycardia group fetal heart rate was increased through whole labor course, but in the tachyc- ardua group the rate was reduced to normal range. (The difference between the control group and study group was highly significant:P<0,001) 3) Fetall amniotic pH, was found to be lower in the control group than in those of glucose laded group both in normal & distress fetus. In the glucose loaded cases the pH was lower in fetal distress group than those of normal group. 4) O2 contents of the corb blood,doth arterial and venous, were slightly higher in the study group than in the control group. 5) CO2 contents od the cord blood, both arterial and venous, were lower in the study group than in the control group. Statistical difference of the umbilical venous blood between the two group was highly significant. It is concluded that the infusion of glucose to the mother during late labor period is beneficial for the fetus to overcome possible distress during the birth.