1. 희유한 Arrhenoblastoma의 일치험예를 보고하는 동시에 그에 관한 문헌적고찰을 하였다. 2. 적출한 종양은 우측에 발생한 남성화난소종양이었으며 병리조직학적검사로써 중간형임을 알았다. 3. 본증환자에 있어서 수술후 2개월후에 다시 여성화증상을 볼 수 있었다.

The author has submitted a case report of arrhenoblastoma of the ovary of a 36 year-old, married, nulliparous Korean woman. She complained of amenorrhea since 28 years of age, accompanied by atrophy of the breasts and external genitalia, and deepening of her voice. Her clitoris became hypertrophied. Hair growth of male type occured over the body and face. Although there was almost no change in her character, her libido was said to have been more active after cessation of her menstruation. Loss of weight and general weakness became gradually marked. She eventually felt abdominal fullness and discomfort. A tumor of the right ovary was treated by unilateral oophorectomy. Gross pathology of the tumor removed: Right solid ovarian tumor. Size; 5.5×8.0×10.0cm Weight; 200gm. Shape; oval-shaped. Capsule; well encapsulated with glastening, translucent and serous capsule with an irregular surface. Cut surface; pale yellow in general, grayish whitish in places. Consistence; rubbery, several fingertip-sized hard nodules could be palpated in the tumor. Microscopic findings of the tumor: The specimen showed a tubular and adenomatous pattern. The tubular formation in general was not perfect and not resemble testicular tubules. In some areas the tubular formation was difficult to identify. The spec imen was almost replaced by tumor cells. Under the high magnification the nuclei of the individual cells were large and hyper-and poly-chromatic and differed greatly in size. A great many vacuoles of various size in nuclei were noted. Microscopic diagnosis: Arrhenoblastoma, intermediate type. Two months following operation she showed refeminization. On arrhenoblastoma, historical considerations, histogenesis, pathology, clinical symptoms and signs, it`s relationship to pregnancy, malignity and recurrence, hereditary relationship, hormone, secretion of the tumor and it`s treatment were briefly discussed.