Angiodysplasia is one of the most common lesions of the gastrointestinal tract that can give rise to clinically significant bleeding. It is associated with renal failure, aging, and aortic stenosis. Gastrointestinal bleeding combined with aortic stenosis is caused by low cardiac output, increased bleeding tendency or defective connective tissue bands in the angiodysplasia. Segmental resection of those portions containing the angiodysplastic lesions has been considered the definitive treatment for patient who are symptomatic because of chronic blood loss. There are scattered reports that recurrent bleeding from gastrointestinal angiodysplasia has ceased after aortic valve replacement. But, in other cases, recurrent bleedings were noted after bowel resection or aortic valve replacememt. Hormone therapy, usually with conjugated estrogen, has been used to treat patients with vascular lesions of the gastrointestinal tracts, in an attempt to reduce or terminate bleeding. We reported a case of cessation of recurrent gastrointestinal bleeding from colonic angiodysplasia combined with aortic stenosis after estrogen-progesterone therapy. (Korean J Gastrointest Endosc 19(Suppl. 2): S76∼S80, 1999)