Postpartum ischemic necrosis of the pituitary gland, known as Sheehan`s syndrome, is well-established clinical entity. In anterior pituitary insufficiency, there is very often a normochromic or hypochromic anemia but pancytopenia secondary to the hypopituitarism is less common. We report a case of pancytopenia due to complete aplasia of the bone marrow associated with Sheehan`s syndrome, in which hormone replacement therapy alone produced full hematological recovery (J Kor Soc Endocrinol 15:595-599, 2000).