Objectives: This study was to investigate the post-stroke depression morbidity and to evaluate the post-stroke depression in relation to activities of daily living by using BDI(Beck`s Depression Inventory)and MBI(Modified Barthel Index) in 45 patients with stroke. Methods: The subjects of this study were 45 stroke patients who were admittied to the Dong-Seo oriental hospital. The post-stroke depression was determined by using the BDI and the evaluation of activities daily living was measured by using the MBI Collected data analysis were completed by using correlation analysis. Results: 1. The post-stroke depression morbidity was 30%. 2. The post-stroke depression have no significant correlation with activities of daily living skills. Conclusions: This study shows that the post-stroke depression have no significant correlation with impairment in activities of daily living. Advanced studies are required to investigate other factors that influence post-stroke depression and post-stroke depression follow-up studies.