平均體重 30 g의 향어에 過酸化物價 98 meq/㎏된 配合飼料를 4個月間 投與한 結果 이들 향어의 肝臟, 脾臟, 腎臟에는 많은 ceroid가 沈着되었다.
이를 除去하기 위하여 glutathione을 添加한 飼料를 投與하여 그 治療效果를 實驗하였다. 향어 1㎏당 glutathione 有效成分을 1日 3㎎ 및 6㎎ 섭취시키고 10日 및 20日 後에 檢査한 結果 20日間 投與하면 治療效果가 뚜렷함을 알았다.
Glutathione을 6㎎, 20日間 投與한 향어의 血液 性狀은 hematocrit 값, 總蛋白質量, 總 cholesterol量, glucose 값이 正常과 近似하였으며 非正常値였던 GOT, GPT 값은 正常値로 향하여 減少되었다.
Nutritional ceroidosis accompanied with histopathological changes such as myopathy and visceral ceroidosis, was experimentally induced by feeding the oxidized feed with the peroxide value of 98meq/㎏, to common carp resulting in some motalities of carp. To see the effect of treacetment survivors of the above fish were orally administered by feeding diets containing daily doses of 3㎎ and 6㎎ of glutathione per ㎏ fish for 10 days or 20 days. While control and 3㎎ dosage group retained viscerral ceroidosis and showed evidence myopathy histo pathologically, the fish treated with 6㎎ of glutathione for 20days showed obvious reduction of macrophages of ceroid in the viscera.