18.97.14.80
18.97.14.80
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SCIE SCOPUS
Purification and Properties of Phenylalanine Ammonia - lyase from Chinese Cabbage
(Hye Won Lim) , (Jae Hoon Sa) , (Tae Soo Kim) , (Eun Hee Park) , (Soo Sun Park) , (Chang Jin Lim)
BMB Reports vol. 31 iss. 1 31-36(6pages)
UCI I410-ECN-0102-2009-470-006691832

Phenylalanine ammonia-lyase (PAL; EC 4.3.1.5), the first enzyme in the phenylpropanoid biosynthesis, catalyzes the elimination reaction of ammonium ion from L-phenylalanine. PAL was purified from the cytosolic fraction of Chinese cabbage (Brassica campestris ssp. napus var. pekinensis) through ammonium sulfate fractionation, DEAE-cellulose chromatography, Sephadex G-200 chromatography, and Q-Sepharose chromatography. It consists of four identical subunits, the molecular mass of which was estimated to be about 38,000 daltons on SDS-PAGE. The optimal pH and temperature of the purified enzyme are 8∼9 and 45℃ respectively. Its activity is greatly inhibited by Zn^(2+) ion, and strongly activated by caffeic acid. The purified PAL has some different characteristics compared to those obtained with other PALS.

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