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18.97.14.84
18.97.14.84
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SCIE SCOPUS
Effect of Polycomb Group Mutants on the Expression of Ultrabithorax in the Visceral Mesoderm of the Drosophila
( Seung Hoon Choi , Dal Hyun Lee , Jang Gyu Lee , Sang Hak Jeon )
UCI I410-ECN-0102-2009-470-007057629
This article is 4 pages or less.

The Polycomb (Pc) group genes encode repressors that restrict expression of homeotic genes to precise domains along the anterior-posterior (A-P) axis. We present how three of Pc-group mutants, Polycomb, extra sex comb (esc) and pleiohomeoitc (pho) genes, affect the expression of the Ultrabithorax (Ubx) in the visceral mesoderm. Ubx is normally expressed in the visceral mesoderm of PS7 and involved in gut morphogenesis. We made fly stocks containing Ubx^(lacz) and the Pc-group mutants. Zygotic emhryos from Pc and embryos showing maternal effects of esc and pho were used to see the expression of β-galactosidase using X-gal and anti-β-gal antibody. pho maternal effect mutant showed very weak ectopic expression. However, Pc zygotic mutant and esc maternal effect mutant showed strong homeotic transformation. This indicates that Pc group genes act as a repressors to maintain precise domain of Ubx expression in the visceral mesoderm.

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