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SCIE SCOPUS
Effect of 3 - Aminobenzamide on Chromosome Aberrations Induced by Ethyl Methanesulfonate or Bleomycin in Synchronized Chinese Hamster Ovary Cells
( Inn Young Kang , Eun Joo Shin , Kyung Il Um )
Genes & Genomics 12권 4호 391-391(1pages)
UCI I410-ECN-0102-2009-470-007054299
이 자료는 4페이지 이하의 자료입니다.

The effect of 3-aminobenzamide (3AB), an inhibitor of polyadenosine diphosphoribose polymerase, on chromosome aberrations induced by ethyl methanesulfonate (EMS) or bleomycin (BLM) were investigated in Chinese hamster ovary cells at various stages of cell cycle. 3AB (5mM) alone did not affect the frequencies of chromosome aberrations over controls. The frequencies of chromosome aberrations by EMS were increased during late G₁ and early S phases. BLM showed the stage sensitivity to chromosome aberrations in G₂ phase. Post-treatment with 3AB did not affect the frequencies of chromosome aberrations induced by BLM in all stages and induced by EMS in mid S and G₂ phases.

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