The relationship between selenium and vitamin E has attracted considerable attention. Detailed feeding experiments with laboratory animals have shown a certain relation betvveen the symptoms of vitamin E deficiency and selenium, but up to now the underlying mechanisms have remained obscure. We have used activation analysis to determine whether a deficiency of vitamin E alters selenium content of certain typical organs. Selenium, garlic and vitamin E supplemented diet was depleted hatched chick breeding. At an age of three weeks the chicks were killed and preparations of blood, skin, muscle, liver, kidney, testis and ovary were made. In order to assay the selenium content of some 100 preparations in a reasonable time, a fast method of analysis was chosen using the 18 sec. ^(77m) Se. Further details of the selenium vitamin E mechanism will be presented.