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조선대학교 치의학연구원(구 조선대학교 구강생물학연구소)> 구강생물학연구> Periodontal disease and vasculogenic erectile dysfunction: a longitudinal health-examinee cohort study in South Korea

KCI등재

Periodontal disease and vasculogenic erectile dysfunction: a longitudinal health-examinee cohort study in South Korea

Jae-hong Lee , Yeon-tae Kim , Jung-kyu Choi , Seong-nyum Jeong , Seong-ho Choi
  • : 조선대학교 치의학연구원(구 조선대학교 구강생물학연구소)
  • : 구강생물학연구 41권3호
  • : 연속간행물
  • : 2017년 09월
  • : 120-126(7pages)

DOI


목차

서 론
재료 및 방법
결 과
고 찰
결 론
감사의 글
Conflict of Interest
ORCID
References

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초록 보기


						
Data was collected for the period 2002 and 2013, from The National Health Insurance Service Health-Examinee Cohort Database, to evaluate the association between periodontal disease (PD) and vasculogenic erectile dysfunction (VED). Univariate and multivariate logistic regression models applied to a longitudinal retrospective database assessed the association between PD and VED, while adjusting for confounders of socio-demographic factors (age, household income, insurance status, health status, residence area, and smoking status) and systemic disease (cerebral infarction, myocardial infarction, angina pectoris, hypertension, diabetes mellitus, osteoporosis, lipid metabolism disturbances, and obesity). The univariate analysis revealed that VED was positively and significantly related to PD (OR = 2.07; 95% CI 1.73-2.49; P < 0.001). This was confirmed in the multivariate analysis, after adjusting for socio-demographic and systemic disease (OR = 1.45; 95% CI 1.21-1.75; P < 0.001). Using information from a longitudinal retrospective cohort database and considering the limitations of this study, we found positive and significant associations between PD and VED. Further studies are required to assess the mechanism underlying the association between PD and VED.

UCI(KEPA)

I410-ECN-0102-2018-500-000694295

간행물정보

  • : 의약학분야  > 기초치의학
  • : KCI등재
  • :
  • : 계간
  • : 2508-2558
  • : 2508-2566
  • : 학술지
  • : 연속간행물
  • : 1978-2019
  • : 1393


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발행기관 최신논문
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1Alcohol ingestion reduced acetylcholine-binding protein in the submandibular gland of the rat

저자 : Bo Hyun Jung , Ki-yeon Yoo

발행기관 : 조선대학교 치의학연구원(구 조선대학교 구강생물학연구소) 간행물 : 구강생물학연구 41권 3호 발행 연도 : 2017 페이지 : pp. 107-113 (7 pages)

다운로드

(기관인증 필요)

초록보기

Continuous alcohol ingestion may lead to various dental diseases because a hyposalivation. In this study, we investigated changes in pathology and choline acetyltransferase (ChAT, an enzyme for synthesis of acetylcholine) in the brain and acetylcholine-binding protein (AchBP, a protein responsible for modulation of synaptic transmission in cholinergic synapses) in the submandibular gland after alcohol ingestion. There was no change in neuronal death and expression of ChAT in superior salivary nucleus after alcohol ingestion. In the submandibular gland, expression of AchBP were significantly reduced after alcohol ingestion. Therefore, decrease of saliva secretion by alcohol ingestion is less related to damage of neurons in the superior salivary nucleus and decrease of acetylcholine synthesis or cholinergic neurotransmission.

2The susceptibility of antibiotics for intracanal bacteria removal using E. faecalis biofilm model

저자 : Su-hee Go , So-hee Kim , In-chol Kang , In-nam Hwang , Won-mann Oh , Yun-chan Hwang

발행기관 : 조선대학교 치의학연구원(구 조선대학교 구강생물학연구소) 간행물 : 구강생물학연구 41권 3호 발행 연도 : 2017 페이지 : pp. 114-119 (6 pages)

다운로드

(기관인증 필요)

초록보기

Most root canal procedures are anatomically complex, resulting in insufficient removal of the necrotic pulp by mechanical root canal shaping. This study evaluated the use of antibiotics as canal irrigants for removal of susceptible intracanal bacteria, using an Enterococcus faecalis biofilm model. Enterococcus faecalis biofilm was developed in the root canal and test tube. For the experiments, sodium hypochlorite (NaOCl), augmentin and erythromycin were used as intracanal irrigants. The test tubes and canals were prepared and irrigated with phosphate buffered saline (PBS), NaOCl, augmentin and erythromycin. Bacterial samples were collected after irrigation in the test tube models on day 1, and from the tooth model on days 1, 4 and 7. The surface of each sample and attached pattern of the bacteria was also analyzed by examining under scanning electron microscopy (SEM). The antibacterial study using 10 ml test tubes (n=10) revealed that 5% NaOCl, augmentin and erythromycin inhibited bacterial growth relative to PBS. In the tooth model, NaOCl, augmentin and erythromycin inhibited bacterial growth significantly (all p<0.05) at days 4 and 7, relative to PBS. Compared to day 1, bacterial density of all groups reduced at day 7, and changes in cell morphology were observed in all experimental groups. Our studies revealed evidence of significant differences in the antimicrobial efficacy at days 4 and 7, upon irrigation with augmentin and erythromycin versus PBS, in root canals infected with E. faecalis.

3Periodontal disease and vasculogenic erectile dysfunction: a longitudinal health-examinee cohort study in South Korea

저자 : Jae-hong Lee , Yeon-tae Kim , Jung-kyu Choi , Seong-nyum Jeong , Seong-ho Choi

발행기관 : 조선대학교 치의학연구원(구 조선대학교 구강생물학연구소) 간행물 : 구강생물학연구 41권 3호 발행 연도 : 2017 페이지 : pp. 120-126 (7 pages)

다운로드

(기관인증 필요)

초록보기

Data was collected for the period 2002 and 2013, from The National Health Insurance Service Health-Examinee Cohort Database, to evaluate the association between periodontal disease (PD) and vasculogenic erectile dysfunction (VED). Univariate and multivariate logistic regression models applied to a longitudinal retrospective database assessed the association between PD and VED, while adjusting for confounders of socio-demographic factors (age, household income, insurance status, health status, residence area, and smoking status) and systemic disease (cerebral infarction, myocardial infarction, angina pectoris, hypertension, diabetes mellitus, osteoporosis, lipid metabolism disturbances, and obesity). The univariate analysis revealed that VED was positively and significantly related to PD (OR = 2.07; 95% CI 1.73-2.49; P < 0.001). This was confirmed in the multivariate analysis, after adjusting for socio-demographic and systemic disease (OR = 1.45; 95% CI 1.21-1.75; P < 0.001). Using information from a longitudinal retrospective cohort database and considering the limitations of this study, we found positive and significant associations between PD and VED. Further studies are required to assess the mechanism underlying the association between PD and VED.

4Suggestion for understanding and activation of the nursing home dentist system

저자 : Jung-min Kwag , Inn-im Park , Mee-kyoung Son

발행기관 : 조선대학교 치의학연구원(구 조선대학교 구강생물학연구소) 간행물 : 구강생물학연구 41권 3호 발행 연도 : 2017 페이지 : pp. 127-133 (7 pages)

다운로드

(기관인증 필요)

초록보기

Various medical policies for elderly patients have been introduced in the era of aging. Recent implementation of nursing home dentist systems is a positive opportunity to recognize the significance of oral health care in managing general healthcare and improving the quality of life for elderly people. In addition, it is necessary to strengthen dentists` competencies and key roles in recovering oral function and rehabilitation with changes in the customer-oriented dental care paradigm. This study suggests the path towards stabilizing and activating nursing home dentist systems by understanding the background and current status of nursing home dentist systems, and identifying ways of improving the systems.

5The study on the participation of Korean dentists in public posts

저자 : Ja-won Cho , Su-hyun Shim

발행기관 : 조선대학교 치의학연구원(구 조선대학교 구강생물학연구소) 간행물 : 구강생물학연구 41권 3호 발행 연도 : 2017 페이지 : pp. 134-140 (7 pages)

다운로드

(기관인증 필요)

초록보기

There have been few reports about the manpower planning of dentists in the public sector in Korea. The purpose of this study was to research dentists` opinions about the public posts, and to suggest public health policies for the new dental manpower position. A total of 536 dentists were asked to fill out questionnaires inquiring about their opinions of public posts. We used an online survey methodology to involve 500 participants. The chi-square tests and frequency distributions were implemented to analyze the dentists` opinions about the public posts. The significance level of 0.05 was applied. A statistical package SPSS 21.0 was used for the analysis. An overwhelming majority of dentists (95.6%) answered that it is necessary to set up public posts for dentists. Respondents pointed out that the Korean Dental Association (35.5%) and the Ministry of Health and Welfare (33.2%) were the main institutes that should carry out this process. Especially, 47.4% of dentists answered they would quit their job if they had opportunities to fill public posts. Most dentists wanted to work as administrative officials (36.3%) in the public sector. Many dentists (62.4%) wanted to contribute to public welfare as health care professionals in public posts. Most of all, respondents (95.6%) answered that it is imperative to improve the manpower system of dentists in public posts.

6Future perspective of new tooth creation

저자 : Mouetaz Kheirallah

발행기관 : 조선대학교 치의학연구원(구 조선대학교 구강생물학연구소) 간행물 : 구강생물학연구 41권 3호 발행 연도 : 2017 페이지 : pp. 141-146 (6 pages)

다운로드

(기관인증 필요)

초록보기

Currently, outcomes of dental stem cells studies indicate that the tooth is an available source for clinical application. Finding a universal cell that can morph into many several types of oral tissues is a key for new tooth creation. If dental stem cells are isolated to form new tooth buds, with creation of an imitative condition to the embryonic jaw, this will be a revolutionary new way to replace a missing tooth. Although investigators have created tooth-like structures in studies, so far, later dental stem cells investigations will be able to create a workable vascularized implant in the human body. This review study discusses current challenges in creating a biological environment that mimics the condition of teeth as they form in an embryo.

7The prognosis of autotransplanted tooth on molar region: 5 years follow up cases

저자 : Yong Yoon , Yong-gun Kim , Jo-young Suh , Jae-mok Lee

발행기관 : 조선대학교 치의학연구원(구 조선대학교 구강생물학연구소) 간행물 : 구강생물학연구 41권 3호 발행 연도 : 2017 페이지 : pp. 147-152 (6 pages)

다운로드

(기관인증 필요)

초록보기

Tooth autotransplantation is the transplantation of embedded, impacted, or erupted teeth from one site to surgically prepared sockets or extraction sites within the same individual. Tooth autotransplantation is a valuable method to replace missing teeth, instead of other procedures like dental implants or prosthetic replacements. Discrimination of indication and consideration of delicate factors affecting the results is important to success in the procedure. This study reports a 5 year clinical observation of two different cases.

8Treatment of pre-eruptive intracoronal resorption: Case report

저자 : So-young Kim , Sang-ho Lee , Nan-young Lee , Young-mi Yoon , Sung-ok Im

발행기관 : 조선대학교 치의학연구원(구 조선대학교 구강생물학연구소) 간행물 : 구강생물학연구 41권 3호 발행 연도 : 2017 페이지 : pp. 153-157 (5 pages)

다운로드

(기관인증 필요)

초록보기

Pre-eruptive intracoronal resorption is a rare disease defined as an intracoronal radiolucent lesion. Most are revealed through casual radiological examinations, and are clinically identifiable after eruption. The possible causes of lesions include congenital abnormalities, systemic fluoride uptake, external factors after tooth formation, and eruption of the tooth; however, no definite etiology has been found. Early diagnosis through regular examination is therefore considered to be the best diagnostic method. Treatment may differ depending on the size and progression of the lesion, but conservative treatment is recommended. This case report describes two cases where the lesions were accidentally found while performing a radiologic examination addressing other issues. It is the clinician`s responsibility to identify the size of the lesion and the expected eruption time, and to execute the appropriate treatment.

9Maxillary total arch distalization using midpalatal mini-implant: Case report

저자 : Chang-bok Song , Sung-hoon Lim

발행기관 : 조선대학교 치의학연구원(구 조선대학교 구강생물학연구소) 간행물 : 구강생물학연구 41권 3호 발행 연도 : 2017 페이지 : pp. 158-166 (9 pages)

다운로드

(기관인증 필요)

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Orthodontic mini-implant is usually placed in the buccal interdental area for molar distalization or total arch distalization. However, this requires timely replacement of the mini-implant to prevent contact between root and mini-implant and ensuing root resorption. Alternatively, midpalate may be considered as the mini-implant placement site because it has considerably dense bone and there is no interference with roots. Also, distalization forces may be designed to pass through the center of resistance of dentition for translatory distal movement. In this case report, end-on Class II occlusion with lip protrusion was successfully treated by applying distal forces from a transpalatal arch to a lever attached to two midpalatal mini-implants. Anti-rotation bends were bent on transpalatal arch to prevent mesial rotation of first molars during distalization. Another benefit of this approach is that molar distalization may be initiated at the beginning of treatment because distal tipping of molars can be prevented by applying distal force at the level of the center of resistance of molars thus eliminating the need of stiff rectangular archwire. With this approach, time-consuming molar distalization may be initiated at the beginning of treatment and therefore, overall treatment duration can be reduced.

10Numb chin syndrome with metastatic malignancy in hyperparathyroidism: Case report

저자 : Byung-yoon Roh , Jong-mo Ahn , Jin-soo Kim , Yo-seob Seo

발행기관 : 조선대학교 치의학연구원(구 조선대학교 구강생물학연구소) 간행물 : 구강생물학연구 41권 3호 발행 연도 : 2017 페이지 : pp. 167-172 (6 pages)

다운로드

(기관인증 필요)

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Numb chin syndrome (NCS) is sensory neuropathy characterized by numbness in the chin and lower lip, involving distribution of the mental nerve. Causes of NCS may be of regional origin, a systemic disease, and malignancy. In this study, we report a case of NCS occurring as a first symptom of malignant metastasis in a 57-year-old female patient diagnosed with hyperparathyroidism.

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