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대한피부과학회> 대한피부과학회지> 원저 : 수두와 대상포진 환자에서 수두대상포진 바이러스에 대한 혈청 내 면역글로불린 M, G의 임상적 의의

KCI등재SCOUPUS

원저 : 수두와 대상포진 환자에서 수두대상포진 바이러스에 대한 혈청 내 면역글로불린 M, G의 임상적 의의

Original Article : Clinical Significance of Serum Varicella Zoster Virus Immunoglobulin M and G in Varicella and Herpes Zoster

김영균 ( Young Gyun Kim ) , 백준오 ( Jun Oh Paek ) , 김정수 ( Joung Soo Kim ) , 유희준 ( Hee Joon Yu )
  • : 대한피부과학회
  • : 대한피부과학회지 53권6호
  • : 연속간행물
  • : 2015년 07월
  • : 441-448(8pages)

DOI


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Background: The presence of serum varicella zoster virus (VZV) immunoglobulin M and G (IgM and IgG) aid diagnosis of and confirmation of immunization against varicella and herpes zoster. However, the relationship between serum VZV IgM and IgG and the clinical characteristics of VZV infection remains unclear. Objective: We evaluated quantitative changes in serum VZV IgM and IgG in accordance with the clinical features of varicella, herpes zoster, and disseminated herpes zoster compared with a normal control group. Methods: A total of 922 patients were classified into 3 groups: varicella, herpes zoster, and disseminated herpes zoster. We assessed serum VZV IgM and IgG titers in association with age, severity of skin lesions, duration of skin lesions, immune status, and neurologic complications. Results: In patients with varicella and herpes zoster, serum antibody titer varied significantly depending on age and the duration of skin lesions. A high serum VZV IgM titer was related to varicella or disseminated herpes zoster viremia. In herpes zoster, elevated antibody titers, especially VZV IgM, were associated with severe skin lesions and the presence of neurologic complications. Conclusion: Serologic data for varicella and herpes zoster varied according to clinical features. A high serum VZV IgM titer was associated with an unfavorable clinical course of herpes zoster. (Korean J Dermatol 2015;53(6):441∼ 448)

UCI(KEPA)

I410-ECN-0102-2015-500-001886428

간행물정보

  • : 의약학분야  > 피부과학
  • : KCI등재
  • : SCOPUS
  • : 월간
  • : 0494-4739
  • :
  • : 학술지
  • : 연속간행물
  • : 1960-2019
  • : 9274


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1원저 : 안산 및 경기 서남부 지역 소아 감염 피부 질환의 기술 역학적 고찰(2003∼2013)

저자 : 이지민 ( Ji Min Lee ) , 김일환 ( Il Hwan Kim )

발행기관 : 대한피부과학회 간행물 : 대한피부과학회지 53권 6호 발행 연도 : 2015 페이지 : pp. 423-429 (7 pages)

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Background: Pediatric infectious skin diseases are different from their counterparts in adults, since the sources of infection and disease progressions are distinct. To our knowledge, there have been no reports of epidemiologic studies of pediatric infectious skin diseases in Korea. Objective: The purpose of this study was to evaluate the distribution of pediatric infectious skin diseases in the Ansan and Southwestern area of Gyeonggi-do, and to compare the results with previous reports about general pediatric dermatoses. Methods: The authors retrospectively evaluated 4,366 cases of pediatric infectious skin diseases from July 2003 to June 2013 in the Department of Dermatology at Korea University Ansan Hospital. The monthly, seasonal, and annual incidences, as well as the ages and genders of the patients were evaluated. Results: The study included 2004 (45.0%) girls and 2362 (55.0%) boys. The most frequent age of infection was 4 to 6 years old (range 0∼15 years), and the peak incidences occurred in July, August, and January. The most common infectious dermatoses were viral (76.0%), bacterial (11.5%), fungal (8.3%), and parasitic (4.0%). The 10 most common pediatric infectious skin diseases were viral wart (45.8%), molluscum contagiosum (20.9%), impetigo (10.3%), tinea (7.1%), scabies (3.8%), herpes zoster (2.5%), varicella (1.6%), herpes simplex (1.5%), eczema herpeticum (1.1%), and cellulitis (0.9%). Conclusion: Compared to previously published reports, the distribution of pediatric infectious skin diseases has changed and was different from general pediatric dermatoses. (Korean J Dermatol 2015;53(6):423∼429)

2원저 : 달팽이 점액 함유 크림의 항노화 효과

저자 : 김범준 ( Beom Joon Kim ) , 노연아 ( Yeon A No ) , 이용희 ( Yonghee Lee ) , 김명남 ( Myung Nam Kim ) , 홍창권 ( Chang Kwon Hong ) , 유광호 ( Kwang Ho Yoo ) , 김용민 ( Yong Min Kim ) , 황정현 ( Jung Hyun Hwang ) , 공수연 ( Su Yeon Kong )

발행기관 : 대한피부과학회 간행물 : 대한피부과학회지 53권 6호 발행 연도 : 2015 페이지 : pp. 430-436 (7 pages)

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Background: A cream made from mucus secreted by snails contains 80% mucin, as well as glycosaminoglycan, allantoin for skin rejuvenation, glycolic acid for keratin removal, and collagen and elastin, which are components of dermis. Objective: The goal of the present study was to evaluate the efficacy of using cream containing mucus secreted by snails to reduce wrinkles, improve skin elasticity, restore dermal density, and lift the skin. Methods: Cream containing mucus secreted by snails was applied to the lateral epicanthal areas and the left cheek of 10 subjects for 4 weeks twice per day. Wrinkles, skin elasticity, dermal density, and skin tightening were evaluated at baseline and 2 and 4 weeks. A patient survey was conducted at 4 weeks. Results: There were statistically significant differences between baseline and 4 weeks after applying the cream in terms of wrinkles, skin elasticity, dermal density, and skin tightening (p<0.05). Conclusion: Use of cream containing mucus secreted by snails seems to be effective for anti-aging of the skin. Long term follow up studies, such as 3 or 6 months, to confirm the efficacy of the cream should be conducted involving a larger number of patients. (Korean J Dermatol 2015;53(6):430∼436)

3원저 : 인터넷상 피부질환 정보에 대한 연구: 여드름

저자 : 정도선 ( Do Seon Jeong ) , 김지연 ( Chi Yeon Kim )

발행기관 : 대한피부과학회 간행물 : 대한피부과학회지 53권 6호 발행 연도 : 2015 페이지 : pp. 437-440 (4 pages)

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Background: The internet is a growing source of information for patients, with increasing numbers of people searching for health information on the web. Patients with acne attempt to search for medical information from the internet. Objective: The purpose of this study is to investigate the current information of acne on the internet. Methods: We chose the largest portal sites to investigate the current information of acne and search for 'acne'. Results: 5.3% of the information provided by question-and-answer platform were written by dermatologist. 0.7% of the information provided by personal blog were written by dermatologist. 1.4% of the information provided by internet message board were written by dermatologist. Overall, only 2.4% of the information were written by dermatologist for provide the medical information. Conclusion: The internet provides a great deal of information in many types of resources. However, the quality of information has been more of a concern. Dermatologists should continue to counteract inaccurate information by providing quality information on the internet. Dermatologists should be more aware of the health-related online information and should guide patients to take the accurate information. (Korean J Dermatol 2015;53(6):437∼440)

4원저 : 수두와 대상포진 환자에서 수두대상포진 바이러스에 대한 혈청 내 면역글로불린 M, G의 임상적 의의

저자 : 김영균 ( Young Gyun Kim ) , 백준오 ( Jun Oh Paek ) , 김정수 ( Joung Soo Kim ) , 유희준 ( Hee Joon Yu )

발행기관 : 대한피부과학회 간행물 : 대한피부과학회지 53권 6호 발행 연도 : 2015 페이지 : pp. 441-448 (8 pages)

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Background: The presence of serum varicella zoster virus (VZV) immunoglobulin M and G (IgM and IgG) aid diagnosis of and confirmation of immunization against varicella and herpes zoster. However, the relationship between serum VZV IgM and IgG and the clinical characteristics of VZV infection remains unclear. Objective: We evaluated quantitative changes in serum VZV IgM and IgG in accordance with the clinical features of varicella, herpes zoster, and disseminated herpes zoster compared with a normal control group. Methods: A total of 922 patients were classified into 3 groups: varicella, herpes zoster, and disseminated herpes zoster. We assessed serum VZV IgM and IgG titers in association with age, severity of skin lesions, duration of skin lesions, immune status, and neurologic complications. Results: In patients with varicella and herpes zoster, serum antibody titer varied significantly depending on age and the duration of skin lesions. A high serum VZV IgM titer was related to varicella or disseminated herpes zoster viremia. In herpes zoster, elevated antibody titers, especially VZV IgM, were associated with severe skin lesions and the presence of neurologic complications. Conclusion: Serologic data for varicella and herpes zoster varied according to clinical features. A high serum VZV IgM titer was associated with an unfavorable clinical course of herpes zoster. (Korean J Dermatol 2015;53(6):441∼ 448)

5원저 : 1,064 nm Q-switched Nd:YAG 레이저를 이용한 백서 피부의 반영구화장 제거: 반영구 화장 후 레이저 치료 시간 간격에 따른 반영구화장 제거의 차이에 대한 비교

저자 : 김지연 ( Ji Yeon Kim ) , 정의현 ( Euy Hyun Chung ) , 김현조 ( Hyun Jo Kim ) , 박영립 ( Young Lip Park ) , 황규왕 ( Kyu Uang Whang ) , 이종석 ( Jong Suk Lee ) , 이성열 ( Sung Yul Lee )

발행기관 : 대한피부과학회 간행물 : 대한피부과학회지 53권 6호 발행 연도 : 2015 페이지 : pp. 449-455 (7 pages)

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Background: Various Q-switched (QS) lasers, such as ruby, alexandrite or neodymium:YAG (Nd:YAG) lasers, are used to remove tattoos and permanent makeup. To our knowledge, there has been no indication or guideline published for the optimal time for laser-mediated tattoo removal. Objective: To set a guideline for the optimal irradiation time for tattoo and permanent makeup removal via 1064 nm QS Nd:YAG (QSND) laser, we compared the degree of tattoo removal and skin histologic changes when the irradiation was employed at different time points. Methods: Rat skin was marked with 54 artificial permanent makeup marks with black ink using a permanent makeup machine. The marks were irradiated with a 1064 nm QSND laser on the application day, and 3 days, 5 days, 1 week, 2 weeks, and 3 weeks after application. Pigmentation changes were checked over time using a Mexameterⓡ and skin biopsy. Results: There was no significant difference in the degree of pigment removal as examined by Mexameterⓡ on the day of makeup application compared to 3 days, 5 days, 1 week, 2 weeks, and 3 weeks after application. Histopathologically, the permanent makeup pigments seemed to move from epidermis to superficial and mid dermis with time. The pigments were relatively well removed throughout the epidermis and dermis when the laser was employed 7 days after tattoo application, compared to laser irradiation on the day of application, as viewed histologically. Conclusion: Laser removal of permanent makeup is effective on the day of application, as determined by testing pigment levels. However, based on histopathology, it is recommended to use lasers to remove permanent makeup about a week after application, since the wound repair process is almost complete at that time. (Korean J Dermatol 2015;53(6):449∼455)

6원저 : 아토피피부염 환자에서 체내 거대분자에 대한 산화 스트레스 지표 평가

저자 : 이은일 ( Eunil Lee ) , 오은하 ( Eun Ha Oh ) , 송해준 ( Hae Jun Song ) , 최원준 ( Won Jun Choi ) , 백진옥 ( Jin Ok Baek ) , 이종록 ( Jong Rok Lee ) , 노주영 ( Joo Young Roh )

발행기관 : 대한피부과학회 간행물 : 대한피부과학회지 53권 6호 발행 연도 : 2015 페이지 : pp. 456-461 (6 pages)

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Background: Excessive exposure to reactive oxygen species (ROS) or decreased antioxidants leads to damage of proteins, lipids, and DNA. Previous studies suggest that oxidative stress may be important in the pathogenesis of atopic dermatitis. Objective: To investigate whether oxidative stress is increased in atopic dermatitis patients compared to a normal control group, we examined DNA damage, lipid peroxidation, ROS production and antioxidant expression. Methods: Patients with atopic dermatitis (n=16; mean Scoring Atopic Dermatitis [SCORAD] index=53.06) were investigated compared to a normal control group (n=25). To examine DNA damage in the cellular level, we performed comet assays on lymphocytes and granulocytes taken from patients and control group. To measure lipid peroxidation products, urine and plasma malondialdehyde (MDA) levels were analyzed. To examine intracellular redox in lymphocytes, ROS were measured using flow cytometry. Expression of superoxide dismutase (SOD) 1, 2 antioxidants were analyzed using reverse transcription polymerase chain reaction (RT-PCR). Results: Atopic dermatitis patients showed severe DNA damage compared to the control group in both lymphocytes (1.89 and 1.51, respectively, p<0.05) and granulocytes (2.07 and 1.58, respectively, p<0.05). While urine MDA levels were not significantly different between groups (1.64 and 1.13 μM/g respectively, p>0.05), plasma MDA levels were significantly increased in atopic dermatitis patients compared to controls (1.45 and 0.80 μM/g respectively, p<0.005). ROS production by activated lymphocytes was increased in atopic dermatitis patients compared to controls. SOD 1, 2 were expressed in all atopic dermatitis patients without significant increase compared to controls. Conclusion: Increased DNA damage, lipid peroxidation and ROS production in lymphocytes as indices of oxidative stress were observed in moderate to severe atopic dermatitis patients compared to normal control. Although precise mechanism of oxidative stress on the pathogenesis of atopic dermatitis is not defined yet, decreasing ROS exposure or augmenting antioxidant defenses may be alternative therapeutic approaches for atopic dermatitis. (Korean J Dermatol 2015;53(6):456∼461)

7증례 : 잘룩창자암 환자에서 항암치료 후 악화된 파종얕은광선땀구멍각화증 1예

저자 : 김경민 ( Kyung Min Kim ) , 이지현 ( Ji Hyun Lee ) , 김태윤 ( Tae Yoon Kim )

발행기관 : 대한피부과학회 간행물 : 대한피부과학회지 53권 6호 발행 연도 : 2015 페이지 : pp. 462-465 (4 pages)

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Disseminated superficial actinic porokeratosis, a variant of porokeratosis, is an uncommon, hereditary or acquired keratinization disorder. It is characterized histologically by cornoid lamella and clinically by central atrophy with elevated borders. Porokeratosis lesions may be triggered by UV light exposure, infection, hematopoietic malignancies, or immunosuppression, but are rarely reported associated with malignancies of visceral organs. We herein report an unusual case of a patient with colon cancer who noted sudden exacerbation of a previously unrecognized disseminated superficial actinic porokeratosis lesion after being treated with chemotherapy. (Korean J Dermatol 2015;53(6):462∼465)

8증례 : 외국인 이주자에게서 발생한 감각소실을 동반하지 않은 결핵양형 나 1예

저자 : 이승우 ( Seung Woo Lee ) , 김영욱 ( Young Uk Kim ) , 김계정 ( Kea Jeung Kim ) , 허은필 ( Eun Phil Heo )

발행기관 : 대한피부과학회 간행물 : 대한피부과학회지 53권 6호 발행 연도 : 2015 페이지 : pp. 466-469 (4 pages)

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Leprosy is a chronic granulomatous disease caused by Mycobacterium leprae. The prevalence and number of new cases have recently markedly decreased in Korea, and the possibility of leprosy can therefore be clinically overlooked. However, leprosy is still endemic in various regions of the world. A 30 year-old male immigrant from Indonesia presented with an erythematous plaque without sensory loss on his face six months after immigration. The skin lesion was diagnosed as tuberculoid leprosy based on clinico-pathology. (Korean J Dermatol 2015;53(6):466∼469)

9Case Report : Infantile Perianal Pyramidal Protrusion

저자 : 최진화 ( Jin Hwa Choi ) , 김연웅 ( Yeon Woong Kim ) , 김병수 ( Byeong Su Kim ) , 송승현 ( Seung Hyun Sohng ) , 신동훈 ( Dong Hoon Shin ) , 최종수 ( Jong Soo Choi ) , 배영경 ( Young Kyung Bae )

발행기관 : 대한피부과학회 간행물 : 대한피부과학회지 53권 6호 발행 연도 : 2015 페이지 : pp. 470-472 (3 pages)

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A 2-year-old girl presented with a month history of a tender, erythematous pyramidal protrusion on the perineum, anterior to the anus. She had suffered painful defecation due to the protrusion, but had no history of constipation. The family history was negative, and physical examination showed no evidence of associated anal fissuring or skin atrophy. Histological examination revealed epidermal hyperplasia, dermal edema, and hemorrhage with inflammatory cell infiltration. The patient was treated with a CO2 laser to relieve painful defecation. Infantile perianal pyramidal protrusion (IPPP) is characterized by a solitary protrusion observed in the perineal and perianal area. Since IPPP is predominantly observed in female children in the perineal area, it can be misdiagnosed as sexual abuse, anogenital warts, or hemorrhoids. The disease is generally benign and may resolve spontaneously, with the exception of the lichen sclerosus-associated type. Physicians should be aware of IPPP to make an accurate diagnosis. (Korean J Dermatol 2015;53(6):470∼472)

10증례 : 옻닭 섭취 후에 발생한 급성 전신성 발진성 농포증 2예

저자 : 김민성 ( Min Sung Kim ) , 김동진 ( Dong Jin Kim ) , 나찬호 ( Chan Ho Na ) , 신봉석 ( Bong Seok Shin )

발행기관 : 대한피부과학회 간행물 : 대한피부과학회지 53권 6호 발행 연도 : 2015 페이지 : pp. 473-477 (5 pages)

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Rhus chicken is a common health food in Korea and is used as an herbal medicine to cure gastrointestinal diseases such as indigestion, loose stool, and peptic ulcers. Unfortunately, systemic contact dermatitis due to the ingestion of Rhus chicken occasionally occurs and its incidence is increasing. The clinical findings of systemic contact dermatitis induced by ingesting Rhus chicken are maculopapules, erythroderma, erythema multiforme-like lesions, vesicles, wheals, purpura, and pustules. Acute generalized exanthematous pustulosis (AGEP) is an acute generalized pustular eruption characterized by rash with sterile pustules, high fever, and neutrophilia. Most cases are caused by drugs, predominantly β-lactams and macrolide antimicrobials, viral infections, and contact hypersensitivity. Rarely, intake of Rhus chicken can cause AGEP. Herein, we describe two cases of AGEP induced by ingestion of Rhus chicken. (Korean J Dermatol 2015;53(6):473∼477)

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주제별 간행물
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KCI등재 SCOUPUS

대한피부과학회지
57권 10호 ~ 57권 10호

프로그램북(구 초록집)
71권 1호 ~ 71권 1호

KCI등재 SCOUPUS

대한피부과학회지
57권 9호 ~ 57권 9호

프로그램북(구 초록집)
71권 2호 ~ 71권 2호

KCI등재 SCI SCOUPUS

Annals of Dermatology
31권 6호 ~ 31권 6호

프로그램북(구 초록집)
71권 2호 ~ 71권 2호

KCI등재 SCI SCOUPUS

Annals of Dermatology
31권 6호 ~ 31권 6호

KCI등재

대한화장품학회지(J. Soc. Cosmet. Scientists Korea)
45권 3호 ~ 45권 3호

KCI등재 SCOUPUS

대한피부과학회지
57권 8호 ~ 57권 8호

KCI등재 SCI SCOUPUS

Annals of Dermatology
31권 5호 ~ 31권 5호

한국피부장벽학회지
21권 1호 ~ 21권 1호

KCI등재 SCOUPUS

대한피부과학회지
57권 7호 ~ 57권 7호

KCI등재 SCOUPUS

대한피부과학회지
57권 6호 ~ 57권 6호

KCI등재

대한화장품학회지(J. Soc. Cosmet. Scientists Korea)
45권 2호 ~ 45권 2호

KCI등재 SCI SCOUPUS

Annals of Dermatology
31권 44호 ~ 31권 44호

KCI등재 SCI SCOUPUS

Annals of Dermatology
31권 4호 ~ 31권 s4호

KCI등재 SCOUPUS

대한피부과학회지
57권 5호 ~ 57권 5호

KCI등재 SCOUPUS

대한피부과학회지
57권 4호 ~ 57권 4호

프로그램북(구 초록집)
71권 1호 ~ 71권 1호

KCI등재

대한화장품학회지(J. Soc. Cosmet. Scientists Korea)
11권 0호 ~ 26권 2호
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