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대한피부과학회> 대한피부과학회지> 증례 : 영아에서 폐렴구균 예방접종 근접부위에 발생한 고정약진양 국소피부독성반응

KCI등재SCOUPUS

증례 : 영아에서 폐렴구균 예방접종 근접부위에 발생한 고정약진양 국소피부독성반응

Case Report : Pneumococcal Vaccination-Induced Localized Cutaneous Toxic Reaction Mimicking Fixed Drug Eruption on a Nearby Vaccination Injection Site in an Infant

윤상돈 ( Sang Don Yoon ) , 이규석 ( Kyu Suk Lee ) , 조재위 ( Jae We Cho )
  • : 대한피부과학회
  • : 대한피부과학회지 52권2호
  • : 연속간행물
  • : 2014년 02월
  • : 124-128(5pages)

DOI


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Pneumococcus is a very important pathogen for children and elderly people, and causes considerable morbidity and mortality in these groups. Pneumococcal vaccination is relatively safe, and is being increasingly used for the prevention of pneumococcal disease, such as meningitis, pneumonia, otitis media, and bacteremia. Mild adverse reactions of pneumococcal vaccination are relatively common, and include erythema, pain, fever, myalgia, and headaches. However, adverse skin reactions are very rare. Here, we present a case of pneumococcal vaccination- induced localized toxic reaction mimicking fixed drug eruption on a nearby vaccination injection site in an infant, which has not previously been documented in Korea.

UCI(KEPA)

I410-ECN-0102-2014-500-001915508

간행물정보

  • : 의약학분야  > 피부과학
  • : KCI등재
  • : SCOPUS
  • : 월간
  • : 0494-4739
  • : 2713-7627
  • : 학술지
  • : 연속간행물
  • : 1960-2020
  • : 9412


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1종설 : 전기 물리적 에너지를 이용하는 피부 미용치료용 의료기기 사용에 따른 부작용과 대처법

저자 : 정경은 ( Kyung Eun Jung ) , 박준수 ( Jun Soo Park ) , 홍승필 ( Seung Phil Hong ) , 김명화 ( Myung Hwa Kim ) , 박병철 ( Byung Cheol Park )

발행기관 : 대한피부과학회 간행물 : 대한피부과학회지 52권 2호 발행 연도 : 2014 페이지 : pp. 77-81 (5 pages)

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Radio frequency and iontophoresis are two commonly used types of medical skin care equipment, utilizing electrical energy. Radio frequency technology has become an important treatment in aesthetic medicine, and has many applications, including non-ablative tightening of the cutaneous tissue to improve skin laxity and to reduce wrinkles. Iontophoresis on the other hand uses a small electric charge to deliver medicine or other chemicals through the stratum corneum, the principle barrier to percutaneous absorption, without the use of a needle. It is used mainly for aesthetic reasons, including treatment of melasma, and for anti-aging therapy. Effective cosmetic results have been demonstrated for both these techniques in a number of studies. However, recklessness and incorrect use of the machines by unqualified practitioners can cause side effects. Here, we review the possible side effects and related coping strategies associated with radio frequency and iontophoresis.

2원저 : 아토피피부염 환자에서 유성 온천수를 이용한 온천욕의 보조적 치료 효과와 안전성에 대한 연구

저자 : 이해을 ( Hae Eul Lee ) , 김형래 ( Hyeong Rae Kim ) , 임명 ( Myung Im ) , 이영 ( Young Lee ) , 김창덕 ( Chang Deok Kim ) , 이증훈 ( Jeung Hoon Lee ) , 서영준 ( Young Joon Seo )

발행기관 : 대한피부과학회 간행물 : 대한피부과학회지 52권 2호 발행 연도 : 2014 페이지 : pp. 82-88 (7 pages)

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Background: Long-term use of various topical and systemic therapies for atopic dermatitis is associated with cutaneous and systemic adverse effects. Balneotherapy as an adjuvant treatment for atopic dermatitis has been extensively studied, and is considered effective and safe, in many countries. However, there is limited evidence from Korea, with only one previous report on the subject. Objective: The aim of this study was to investigate the therapeutic efficacy and safety of balneotherapy in the treatment of atopic dermatitis in a Korean population. Methods: Thirty atopic dermatitis patients were included in this randomized clinical trial evaluating the therapeutic efficacy of balneotherapy at Yuseong Spa, for four weeks. The patients were assigned to two groups: the control group (allowed treatment only) and balneotherapy group (additionally treated with balneotherapy). Assessment was made at baseline, and after 1, 2, and 4 weeks of treatment. Results: At week 4, compared with the control group, the balneotherapy group showed significantly greater improvement in the eczema area and severity index score, physician`s global assessment, patient`s self global assessment, and in the measured value of transepidermal water loss. The visual analog scale for pruritus in the balneotherapy group decreased, whereas it increased in the control group. None of the patients experienced any adverse events. Conclusion: Our study suggests that balneotherapy may be beneficial, is safe, and may increase the quality of life for patients with atopic dermatitis.

3원저 : 한국인의 옻 항원(Urushiol)에 대한 첩포검사 결과에 관한 연구

저자 : 신수정 ( Soo Jung Shin ) , 김철우 ( Chul Woo Kim ) , 김상석 ( Sang Seok Kim )

발행기관 : 대한피부과학회 간행물 : 대한피부과학회지 52권 2호 발행 연도 : 2014 페이지 : pp. 89-93 (5 pages)

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Background: Allergic contact dermatitis (ACD) due to urushiol is a relatively common phenomenon in Korea. However, there are no recent studies regarding the results of patch tests with urushiol in ACD patients. Objective: The purpose of this study was to analyze the results of the urushiol patch test, and to compare current urushiol sensitivity with findings from previous reports. Methods: Patch test with 0.002% urushiol allergen and a thin-layer rapid use epicutaneous (T.R.U.E.) patch test were performed in 200 patients (67 men and 133 women) who were suspected of having ACD, between July 2011 and July 2013. Patient demographic findings and patch test results were evaluated. Results: Positive reactions to urushiol were observed in 23 patients (11.5%), with a mean age (±standard deviation) of 61.4±10.8 years, which was significantly older than the mean age of 47.6±16.4 years of patients testing negative for urushiol sensitivity (p<0.001). Patients aged 50∼59 years had the highest incidence of a positive reaction, and this difference in urushiol sensitivity according to age groups was statistically significant (p<0.005). A total of 8 (11.9%) of the 67 male patients, and 15 (11.3%) of the 133 female patients showed a positive reaction to urushiol. Of the 23 patients with a positive reaction to urushiol, 19 patients (82.6%) had at least one positive reaction to the T.R.U.E. test allergen, with p-phenylenediamine showing the highest sensitization rates (31.6%). The most frequently affected site in urushiol-positive patients was the face (39.1%). Conclusion: Based on our study results, urushiol sensitivity among Korean ACD patients is a relatively common occurrence, and a patch test with urushiol would be helpful in identifying the causative allergen in ACD patients.

4원저 : 두경부 표피낭종 치료에서 펀치 절개술과 방추형 절제술의 효과 및 재발률에 관한 비교 연구

저자 : 권태광 ( Tae Gwang Kwon ) , 손현호 ( Hyun Ho Son ) , 이숙경 ( Sook Kyung Lee )

발행기관 : 대한피부과학회 간행물 : 대한피부과학회지 52권 2호 발행 연도 : 2014 페이지 : pp. 94-99 (6 pages)

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Background: The removal of epidermal cysts from the head and neck can sometimes be challenging for dermatologists, due to the associated cosmetic effects. Punch incision is an alternative method to the traditional elliptical excision for the removal of epidermal cysts. It is simple to perform with commonly available instruments, and easy to learn. However, there is currently no randomized study directly comparing the long-term results of these two methods in Korea. Objective: The purpose of this study was to evaluate the usefulness of punch incision as compared to elliptical excision for the removal of epidermal cysts, and to identify the characteristics of the lesions most suitable for punch incision. Methods: We conducted a prospective randomized study. A total of 109 patients with non-infected epidermal cysts on the head and neck were randomly assigned to treatment with either punch incision or elliptical excision, between January 2012 and January 2013. Statistical analysis was performed to compare the differences between the two procedures with respect to the demographic data of the patients; size and location of the lesions; operative time; complications; recurrence; cosmetic results; and patient satisfaction. Results: The mean operative time for the punch incision group was significantly shorter than for the elliptical excision group (p<0.05). The cosmetic result scores at 6 months after the operation were significantly higher in the punch incision group, compared to the elliptical excision group (p<0.05). No significant differences were observed between the groups with regards to age, sex, disease duration, location, size, prevalence of complications, and recurrence rate (p>0.05). Conclusion: Punch incision requires less time than elliptical excision, and is associated with superior cosmetic results. Regardless of different demographic characteristics, duration, location, and size, any epidermal cyst on the head and neck can be effectively treated with punch incision. Thus, we suggest that punch incision may be a useful method for removing epidermal cysts of the head and neck.

5원저 : Elravieⓡ 필러 3종에 대한 제형 특성 연구

저자 : 송이섭 ( Yi Seop Song ) , 이용희 ( Yong Hee Lee ) , 김형미 ( Hyeong Mi Kim ) , 손인평 ( In Pyeong Son ) , 정봉열 ( Bong Youl Chung ) , 이종오 ( Jong Oh Lee ) , 임채영 ( Chae Young Lim ) , 박귀영 ( Kui Young Park ) , 이갑석 ( Kap Sok Li ) , 김범준 ( Beom Joon Kim )

발행기관 : 대한피부과학회 간행물 : 대한피부과학회지 52권 2호 발행 연도 : 2014 페이지 : pp. 100-105 (6 pages)

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Background: Hyaluronic acid (HA) is a mucopolysaccharide that occurs naturally throughout the human body, where it attaches to collagen and elastin to form cartilage, and also helps maintain the strength and flexibility of the cartilage that cushions joints. A decline in HA synthesis may lead to a variety of symptoms, ranging from joint discomfort, to wrinkles. Cross-linked HA is a viscoelastic solid that resists in vivo degradation by hyaluronidase for much longer than endogenous HA, and which is also a key ingredient in various cosmetics. Objective: To describe our experience with three kinds of Elravieⓡ fillers. Methods: We obtained images of filler shape using a folliscope. Scanning electron microscopy (SEM) was used to compare particle sizes. Hydrophilic filler is a hydroxyl, and for this reason, we mixed the filler with water. Next, PARKER ink was added to the mixture, and viscosity and elasticity were measured using a rheometer. Results: Among the tested fillers, particle size was largest in the Restylaneⓡ SubQ. Elravieⓡ ultra volume filler was greater in volume than Elravieⓡ deep line, and Elravieⓡ light fillers. We confirmed Elravieⓡ fillers to be hydrophilic. Elravieⓡ ultra volume filler was found to have the highest viscosity and elasticity, whilst Elravieⓡ light filler had the lowest. Conclusion: All three kinds of Elravieⓡ fillers were found to be suitable for human cosmetic use.

6Original Article : Evaluation of the Efficacy, Safety, and Treatment-Related Skin Irritation of Adapalene-Benzoyl Peroxide Combination Gel and Adapalene Gel in Acne Patients: A Randomized Comparative Study

저자 : Hyojin Kim , Jeong Nan Kang , In Ho Park , Ji Sung Chun , Jung Eun Seol , Jong Keun Seo , Ho Suk Sung

발행기관 : 대한피부과학회 간행물 : 대한피부과학회지 52권 2호 발행 연도 : 2014 페이지 : pp. 106-114 (9 pages)

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Background: While adapalene and benzoyl peroxide have both been demonstrated to be effective for the treatment of acne vulgaris, they can also cause skin irritation, resulting in patient incompliance. In addition, the irritation may be severe when adapalene is co-administered with benzoyl peroxide. Objective: The intention of this study was to evaluate the efficacy and safety of adapalene 0.1%-benzoyl peroxide 2.5% fixed-dose combination gel, and adapalene 0.1% gel monotherapy, for the treatment of mild to moderate acne. Any changes in the skin barrier function were also measured. Methods: A total of 52 patients applied adapalene-benzoyl peroxide gel or adapalene gel once daily. The changes in lesion counts, investigator.s global assessment, patient satisfaction, and adverse events were recorded for 6 weeks. The biophysical profiles of the skin, including transepidermal water loss and redness, were measured for 3 weeks. Results: Both agents were effective for the treatment of acne lesions. Adapalene-benzoyl peroxide showed a faster onset of action than adapalene, especially on inflammatory lesions. However, at week 6, both agents showed a similar effect in reducing lesion counts. While most patients in both groups experienced skin irritation from week 1, this gradually reduced. Likewise, the changes in transepidermal water loss and redness showed peak rates at week 1 and 2, but decreased over time. Conclusion: Adapalene-benzoyl peroxide gel is effective for the treatment of acne with a safety profile comparable to adapalene gel. The skin irritation experienced may be associated with the changes in skin barrier disruption, which lasts for 1.2 weeks.

7증례 : 광범위하게 발생한 자궁경부 편평세포암의 피부전이 1예

저자 : 진현주 ( Hyun Ju Jin ) , 김원정 ( Won Jeong Kim ) , 문제호 ( Je Ho Mun ) , 송마가렛 ( Margaret Song ) , 김훈수 ( Hoon Soo Kim ) , 고현창 ( Hyun Chang Ko ) , 김문범 ( Moon Bum Kim ) , 김병수 ( Byung Soo Kim )

발행기관 : 대한피부과학회 간행물 : 대한피부과학회지 52권 2호 발행 연도 : 2014 페이지 : pp. 115-119 (5 pages)

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Carcinoma of the uterine cervix is a common malignancy for women in Korea. It frequently metastasizes to the lungs, bone, or liver, but cutaneous metastasis is rare, with a reported incidence of only 1.3%. In cases of cutaneous metastasis, the lesions present in the forms of nodules, ulcers, or plaques, and are generally located in the abdominal wall, vulva, anterior chest wall, lower extremities, and upper extremities. Here, we describe a case of a 64-year-old woman diagnosed with cutaneous metastases from squamous cell carcinoma of the uterine cervix on both flanks, lower abdominal wall, and both inguinal areas, three years after receiving chemoradiation therapy. At presentation, the primary carcinoma had been resolved completely. Histological and immunohistochemical findings revealed intact epidermis and infiltration of tumor cells in the dermis, which showed positivity for cytokeratin 5/6, cytokeratin 7, and tumor protein 63, consistent with metastatic squamous cell carcinoma of the uterine cervix.

8증례 : 농양과 유사한 신우 이행상피암의 피부전이 1예

저자 : 이주현 ( Joo Hyun Lee ) , 김정은 ( Jung Eun Kim ) , 강훈 ( Hoon Kang )

발행기관 : 대한피부과학회 간행물 : 대한피부과학회지 52권 2호 발행 연도 : 2014 페이지 : pp. 120-123 (4 pages)

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Upper tract urothelial carcinoma (UTUC), which comprises tumors of the ureter and renal pelvis, is a rare genitourinary malignancy. Among these tumors, transitional cell carcinoma (TCC) of the renal pelvis is highly uncommon, and cutaneous metastasis of this tumor is very rare. Herein, we report a case of cutaneous metastasis of TCC of the renal pelvis, clinically mimicking an abscess. A 79-year-old woman was diagnosed with TCC of the left renal pelvis, and underwent wide nephrectomy and chemotherapy in August 2012. She presented with painful, solitary 3 cm sized erythematous dome-shaped mass on the right lower abdomen that had been present for two weeks. We took biopsies of the center and periphery of the mass. Histopathological findings were consistent with cutaneous metastasis of TCC. Immunohistochemical examination showed strongly positive cytokeratin 7 staining, and negative cytokeratin 20 and thrombomodulin staining.

9증례 : 영아에서 폐렴구균 예방접종 근접부위에 발생한 고정약진양 국소피부독성반응

저자 : 윤상돈 ( Sang Don Yoon ) , 이규석 ( Kyu Suk Lee ) , 조재위 ( Jae We Cho )

발행기관 : 대한피부과학회 간행물 : 대한피부과학회지 52권 2호 발행 연도 : 2014 페이지 : pp. 124-128 (5 pages)

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Pneumococcus is a very important pathogen for children and elderly people, and causes considerable morbidity and mortality in these groups. Pneumococcal vaccination is relatively safe, and is being increasingly used for the prevention of pneumococcal disease, such as meningitis, pneumonia, otitis media, and bacteremia. Mild adverse reactions of pneumococcal vaccination are relatively common, and include erythema, pain, fever, myalgia, and headaches. However, adverse skin reactions are very rare. Here, we present a case of pneumococcal vaccination- induced localized toxic reaction mimicking fixed drug eruption on a nearby vaccination injection site in an infant, which has not previously been documented in Korea.

10증례 : 소아에서 발생한 구진성 황색종

저자 : 서지영 ( Ji Young Seo ) , 신문섭 ( Moon Seub Shin ) , 김수진 ( Soo Jin Kim ) , 허식 ( Sik Haw ) , 김성현 ( Seong Hyun Kim )

발행기관 : 대한피부과학회 간행물 : 대한피부과학회지 52권 2호 발행 연도 : 2014 페이지 : pp. 129-132 (4 pages)

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Papular xanthoma is a rare normolipemic xanthomatous skin disease that primarily occurs in adults. While this rare disorder has been documented in children before, all but one case reported in the literature involved a normal lipid profile. The skin lesions of adult papular xanthoma appear to be persistent, whereas in children they generally self-heal within 1∼5 years. Here, we describe a typical case of papular xanthoma in a 22-month-old boy who presented with numerous reddish-yellow papulonodules, 2∼8 mm in diameter, mainly on the face, but also on the upper and lower extremities, and trunk, for 15 months. The lipid profile was normal, and histological studies showed a diffuse monomorphous infiltrate of foamy cells, with some Touton giant cells, in the dermis. The foamy cells stained positive for Cluster of Differentiation (CD) 68, and the Periodic Acid Schiff (PAS) stain was negative. These findings are consistent with the diagnosis of papular xanthoma.

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KCI등재 SCOUPUS

대한피부과학회지
58권 7호 ~ 58권 7호

KCI등재 SCI SCOUPUS

Annals of Dermatology
32권 4호 ~ 32권 4호

KCI등재 SCOUPUS

대한피부과학회지
58권 6호 ~ 58권 6호

KCI등재

대한화장품학회지(J. Soc. Cosmet. Scientists Korea)
46권 2호 ~ 46권 2호

KCI등재 SCOUPUS

대한피부과학회지
58권 5호 ~ 58권 5호

KCI등재 SCI SCOUPUS

Annals of Dermatology
32권 3호 ~ 32권 3호

KCI등재 SCOUPUS

대한피부과학회지
58권 4호 ~ 58권 4호

KCI등재

대한화장품학회지(J. Soc. Cosmet. Scientists Korea)
46권 1호 ~ 46권 1호

KCI등재 SCOUPUS

대한피부과학회지
58권 3호 ~ 58권 3호

KCI등재 SCI SCOUPUS

Annals of Dermatology
32권 2호 ~ 32권 2호

KCI등재 SCOUPUS

대한피부과학회지
58권 2호 ~ 58권 2호

KCI등재

대한화장품학회지(J. Soc. Cosmet. Scientists Korea)
45권 4호 ~ 45권 4호

KCI등재 SCI SCOUPUS

Annals of Dermatology
32권 1호 ~ 32권 1호

KCI등재 SCOUPUS

대한피부과학회지
58권 1호 ~ 58권 1호

KCI등재 SCOUPUS

대한피부과학회지
57권 10호 ~ 57권 10호

프로그램북(구 초록집)
71권 1호 ~ 71권 1호

KCI등재 SCOUPUS

대한피부과학회지
57권 9호 ~ 57권 9호

프로그램북(구 초록집)
71권 2호 ~ 71권 2호

KCI등재 SCI SCOUPUS

Annals of Dermatology
31권 6호 ~ 31권 6호

프로그램북(구 초록집)
71권 2호 ~ 71권 2호
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