논문 상세보기

대한소화기학회> 대한소화기학회지> 종설 : 식생활 습관이 비알코올 지방간에 미치는 영향

KCI등재SCOUPUS

종설 : 식생활 습관이 비알코올 지방간에 미치는 영향

REVIEW : The Role of Diet in Non-alcoholic Fatty Liver Disease

전대원 ( Dae Won Jun )
  • : 대한소화기학회
  • : 대한소화기학회지 61권5호
  • : 연속간행물
  • : 2013년 05월
  • : 243-251(9pages)
피인용수 : 69건

(자료제공: 네이버학술정보)

DOI


목차


					

키워드 보기


초록 보기


						
Prevalence of non-alcoholic fatty liver disease (NAFLD) is about 20-25% in Korean adults population. Obesity is strongly associated with NAFLD and the prevention of obesity is a major public issue. Unfortunately, pharmacological treatment of obesity and NAFLD remains uncertain. Only weight loss by dietary changes been shown to lead to histological improvement in fatty liver. So the nutrition therapy is a cornerstone of treatment for NAFLD. Epidemiologic studies show that saturated fat, trans-fatty acid, carbohydrate, and simple sugar have strong correlation with intrahepatic fat accumulation. But, true associations with specific nutrients still remain unclear. Recently, fructose consumption has been rising in many countries and several epidemiologic studies show that fructose consumption has strong correlation with metabolic diseases. The consumption of excessively added sugar in the pathogenesis of steatohepatitis has received attention. Most clinicians agree with lifestyle modification are effective in histologic improvement. Total energy intake restriction is the most important action to reduce intrahepatic fat accumulation. Macronutrient composition may also have correlation with the development of NAFLD. To reduce the incidence of NAFLD, public statements on optimal dietary education program have been issused. Various specific dietary programs are suggested. Among them low fat diet and low carbohydrate diet are suggested in patients with NAFLD. However, there is no ideal diet to obtain the histological improvement in NAFLD. Further randomised controlled studies about specific diet are needed to determine the long-term benefit and histological improvement by ideal diet. Tailoring diet therapy to a patient`s lifestyle is more important than universal specific dietary program.

UCI(KEPA)

I410-ECN-0102-2013-510-002242068

간행물정보

  • : 의약학분야  > 내과학
  • : KCI등재
  • : SCOPUS
  • : 월간
  • : 1598-9992
  • : 2233-6869
  • : 학술지
  • : 연속간행물
  • : 1968-2020
  • : 5613


저작권 안내

한국학술정보㈜의 모든 학술 자료는 각 학회 및 기관과 저작권 계약을 통해 제공하고 있습니다.

이에 본 자료를 상업적 이용, 무단 배포 등 불법적으로 이용할 시에는 저작권법 및 관계법령에 따른 책임을 질 수 있습니다.

발행기관 최신논문
| | | | 다운로드

1논평 : 한국인 크론병 환자에서 Infliximab의 장기 치료효과 및 반응의 예측인자

저자 : 이강문 ( Kang Moon Lee )

발행기관 : 대한소화기학회 간행물 : 대한소화기학회지 61권 5호 발행 연도 : 2013 페이지 : pp. 241-242 (2 pages)

다운로드

(기관인증 필요)

키워드 보기
초록보기

Clinical Outcome of Treatment with Infliximab in Crohn`s Disease: A Single-Center Experience

2종설 : 식생활 습관이 비알코올 지방간에 미치는 영향

저자 : 전대원 ( Dae Won Jun )

발행기관 : 대한소화기학회 간행물 : 대한소화기학회지 61권 5호 발행 연도 : 2013 페이지 : pp. 243-251 (9 pages)

다운로드

(기관인증 필요)

초록보기

Prevalence of non-alcoholic fatty liver disease (NAFLD) is about 20-25% in Korean adults population. Obesity is strongly associated with NAFLD and the prevention of obesity is a major public issue. Unfortunately, pharmacological treatment of obesity and NAFLD remains uncertain. Only weight loss by dietary changes been shown to lead to histological improvement in fatty liver. So the nutrition therapy is a cornerstone of treatment for NAFLD. Epidemiologic studies show that saturated fat, trans-fatty acid, carbohydrate, and simple sugar have strong correlation with intrahepatic fat accumulation. But, true associations with specific nutrients still remain unclear. Recently, fructose consumption has been rising in many countries and several epidemiologic studies show that fructose consumption has strong correlation with metabolic diseases. The consumption of excessively added sugar in the pathogenesis of steatohepatitis has received attention. Most clinicians agree with lifestyle modification are effective in histologic improvement. Total energy intake restriction is the most important action to reduce intrahepatic fat accumulation. Macronutrient composition may also have correlation with the development of NAFLD. To reduce the incidence of NAFLD, public statements on optimal dietary education program have been issused. Various specific dietary programs are suggested. Among them low fat diet and low carbohydrate diet are suggested in patients with NAFLD. However, there is no ideal diet to obtain the histological improvement in NAFLD. Further randomised controlled studies about specific diet are needed to determine the long-term benefit and histological improvement by ideal diet. Tailoring diet therapy to a patient`s lifestyle is more important than universal specific dietary program.

3원저 : 제주 지역에서 23S rRNA 점 돌연변이와 관련된 Clarithromycin 내성 Helicobacter pylori

저자 : 김태윤 ( Taeyun Kim , , 송현주 ( Hyun Joo Song ) , 신선영 ( Sun Young Shin ) , 김조헌 ( Jo Heon Kim ) , 나수영 ( Soo Young Na ) , 부선진 ( Sun Jin Boo ) , 최은광 ( Eun Kwang Choi ) , 조유경 ( Yoo Kyung Cho ) , 김흥업 ( Heung Up Kim ) , 송병철 ( Byung Cheol Song )

발행기관 : 대한소화기학회 간행물 : 대한소화기학회지 61권 5호 발행 연도 : 2013 페이지 : pp. 252-258 (7 pages)

다운로드

(기관인증 필요)

초록보기

Background/Aims: The point mutations in 23S rRNA gene accounts for the majority of the clarithromycin resistance of Helicobacterpylori. This study aimed to investigate the association between the clarithromycin-resistance of H. pylori and the failure of primary H. pylori eradication therapy in Jeju Island. Methods: Between April 2011 and October 2012, 6,937 patients underwent endoscopy, and H. pylori infection was evaluated in 2,287 patients (33.0%). Total of 110 patients with H. pylori infection were treated with proton pump inhibitor (PPI)-based triple therapy. The result of eradication was evaluated with urea breath test, histology and PCR which were conducted 4 weeks from the last dose of medicine. Results: The patients who had point mutations were 33 (26.0%). A2142G and A2143G mutations were observed in 10 patients (7.9%) and 23 patients (18.1%). Among 110 patients treated with PPI-based triple therapy, the success rate of the eradication therapy was 52.7% (58/110) and 70.7% (58/82) by intention-to-treat and per-protocol analysis, respectively. Fifteen of the 24 patients who failed the eradication therapy showed point mutations; 1 patient (4.2%) showed A2142G mutation and 14 patients (58.3%) showed A2143G mutation. Patients with A2143G mutation H. pylori showed higher failure rate of 87.5%. Patients with A2142G mutation H. pylori showed similar failure rate compared to those of the patients with wild type H. pylori. Conclusions: In Jeju Island, the frequency of 23S rRNA point mutations is similar (26.0%) with other regions of Korea (15.8-31.3%). A2143G mutation is associated with the failure of H. pylori eradication.

4Background/Aims: The point mutations in 23S rRNA gene accounts for the majority of the clarithromycin resistance of Helicobacterpylori. This study aimed to investigate the association between the clarithromycin-resistance of H. pylori and the failure of p

저자 : 남관우 ( Kwan Woo Nam ) , 백명기 ( Myong Ki Baeg ) , 권정현 ( Jung Hyun Kwon ) , 조성훈 ( Soung Hoon Cho ) , 나수진 ( Soo Jin Na ) , 최명규 ( Myung Gyu Choi )

발행기관 : 대한소화기학회 간행물 : 대한소화기학회지 61권 5호 발행 연도 : 2013 페이지 : pp. 259-264 (6 pages)

다운로드

(기관인증 필요)

초록보기

tissue lymphoma. This study was to determine whether H. pylori was associated with colorectal neoplasms in Korean subjects undergoing routine checkup. Methods: A total of 10,082 subjects underwent routine checkups from January 2004 to April 2005. A H. pylori IgG test and stool occult blood test were included in the routine checkup program. Colonoscopy was performed if the stool occult blood test was positive or under subject request. Patients who underwent colonoscopy and had histologically confirmed cases of colorectal neoplasms were designanted as the subject group and those without as the control group. Results: Of the 10,082 subjects, 597 had full colonoscopy. The results identified 9 colorectal carcinomas and 118 adenomas. H. pylori seropositivity was identified in 6 (66%) subjects with colorectal carcinoma, 81 (68.6%) with colorectal adenoma and 248 (52.8%) controls. Subjects having colorectal neoplasms had a significantly higher H. pylori seropositivity rate compared with the controls (OR 1.94, 95% CI 1.28-2.95). This remained significant after adjusting for age, sex, body mass index, HbA1c and total cholesterol (OR 1.90, 95% CI 1.23-2.93). Patients with distal neoplasms also had a significantly higher H. pylori seroposivity rate (OR 1.88, 95% CI 1.17-3.01) which persisted after multivariate adjustment (OR 1.79, 95% CI 1.10-2.94). Conclusions: Subjects with colorectal neoplasms present an increased H. pylori seroprevalence compared with controls. (Korean J Gastroenterol 2013;61:259-264)

5원저 : Ischemic Necrosis of the Cecum; A Single Center Experience

저자 : Ebubekir Gundes , Tevfik Kucukkartallar , Muzaffer Haldun ?olak , Murat Cakir , Faruk Aksoy

발행기관 : 대한소화기학회 간행물 : 대한소화기학회지 61권 5호 발행 연도 : 2013 페이지 : pp. 265-269 (5 pages)

다운로드

(기관인증 필요)

초록보기

Background/Aims: Isolated cecal necrosis is a rare cause of the surgical abdomen. Its manifestation is similar to that of acute appendicitis. Thirteen cases, who were pre-diagnosed with acute abdomen and were finally diagnosed with isolated  cecal necrosis after operation have been evaluated alongside with literature. Methods: The records of 13 patients, who had isolated cecal necroses between 1995 and 2011 at Necmettin Erbakan University Meram Medical School`s General Surgery Clinic (Turkey), were retrospectively evaluated. Results: Eight of the patients were male, whereas 5 were female. Their mean age was 68.0±11.7 (range 51-84) years. All the patients had at least one accompanying disease the most frequent of which were heart failure and chronic renal failure. Ten patients had right hemicolectomy and ileotransversostomy, two had right hemicolectomy and ileostomy, and one had wedge resection to the cecum by the help of linear stapler. Mortality was seen in 5 patients (38%) in the early postoperative period. Conclusions: Isolated cecal necrosis should be considered in elderly patients with chronic diseases presenting with sudden right lower quadrant pains in the differential diagnosis. Isolated cecal necrosis may have a bad prognosis since it is seen in elderly patients with accompanying problems. Therefore, early diagnosis and immediate surgical management if necessary is important to reduce the risk of morbidity and mortality.

6원저 : 단일 기관에서 경험한 크론병에서 Infliximab의 치료 효과

저자 : 김연주 ( Yeon Ju Kim ) , 김정욱 ( Jung Wook Kim ) , 이창균 ( Chang Kyun Lee ) , 박현진 ( Hyun Jin Park ) , 심재준 ( Jae Jun Shim ) , 장재영 ( Jae Young Jang ) , 동석호 ( Suk Ho Dong ) , 김효종 ( Hyo Jong Kim ) , 김병호 ( Byung Ho Kim ) , 장영운 ( Young Woon Chang )

발행기관 : 대한소화기학회 간행물 : 대한소화기학회지 61권 5호 발행 연도 : 2013 페이지 : pp. 270-278 (9 pages)

다운로드

(기관인증 필요)

초록보기

Background/Aims: Our aim was to assess the long-term data regarding efficacy and safety of infliximab (IFX) treatment for refractory Crohn`s disease (CD) patients in our tertiary teaching hospital. Methods: We have retrospectively analyzed the medical records of 89 CD patients who underwent IFX treatment between March 2003 and February 2011 at Kyung Hee University Hospital (Seoul, Korea). The primary outcome measurements were the rates of initial clinical response (CR) at 10 weeks after the 1st IFX infusion and sustained CR at the end of the follow-up. Overall adverse events related to IFX treatment were also evaluated. Results: The mean (SD) follow-up period of eligible 80 patients was 33.7 (21.9) months. A total of 77 patients (96%) showed initial clinical response, but 8 patients showed loss of response to IFX during the follow-up. Finally, 59 patients (59/77, 76.6%) showed sustained CR at the end of the study. Logistic regression analyses showed that an initial CR at 10 weeks was the independent predictor associated with sustained CR (OR 22.286, 95% CI 2.742-132.717, p=0.001). Overall adverse events reported in 18 patients (18/80, 23.3%), including 3 serious infection (pulmonary tuberculosis and herpes zoster). Conclusions: Treatment with IFX was efficacious and relatively safe for refractory CD patients in Korea. An initial CR at 10 weeks was significantly associated with sustained CR.

7증례 : 대량 출혈을 주소로 내원한 공장의 Dieulafoy 병변 1예

저자 : 한민석 ( Min Seok Han ) , 박병규 ( Byung Kyu Park ) , 이상훈 ( Sang Hun Lee ) , 양희철 ( Heui Chul Yang ) , 홍영기 ( Young Ki Hong ) , 최윤정 ( Yoon Jung Choi )

발행기관 : 대한소화기학회 간행물 : 대한소화기학회지 61권 5호 발행 연도 : 2013 페이지 : pp. 279-281 (3 pages)

다운로드

(기관인증 필요)

초록보기

The Dieulafoy lesion is a rare cause of severe gastrointestinal hemorrhage. Although it may occur anywhere in the gastrointestinal tract, the lesion is most commonly located in the stomach, and the small bowel is an extremely uncommon site. Since Dieulafoy lesion in the small bowel is difficult to access by endoscopy, it seems impossible to diagnose and treat by initial endoscopy unlike the lesions in stomach. We experienced a case of Dieulafoy lesion of jejunum with massive hemorrhage in 54-year-old male. Active jejunal bleeding was shown by computed tomography scan and mesenteric angiography. Partial resection of the jejunum was performed. Final pathologic finding revealed Dieulafoy lesion of the jejunum.

8증례 : 70세 남자환자에서 발생한 장 무회전증에 의한 중장염전

저자 : 지병수 ( Byung Soo Jie ) , 김은옥 ( Eun Ok Kim ) , 김진석 ( Jin Seok Kim ) , 이화정 ( Hwa Jeong Lee ) , 송윤미 ( Youn Mi Song ) , 김영신 ( Young Shin Kim ) , 정성훈 ( Sung Hoon Jung ) , 오정환 ( Jung Hwan Oh )

발행기관 : 대한소화기학회 간행물 : 대한소화기학회지 61권 5호 발행 연도 : 2013 페이지 : pp. 282-285 (4 pages)

다운로드

(기관인증 필요)

초록보기

Intestinal malrotation is a congenital disorder that results from the failure of normal bowel rotation and fixation during the 5th gestational week. The incidence of intestinal malrotation is <0.2%, but prompt diagnosis is important because this anomaly can cause midgut volvulus and lead to fatalities. Compared to infants presenting with acute symptoms, such as abdominal pain, vomiting, or diarrhea, adult patients complain of intermittent self-limited abdominal pain. We present a case of intestinal malrotation complicated by midgut volvulus improved with conservative care in a 70-year-old man. The diagnosis was suggested on the basis of imaging findings.

9CASE REPORTS : Repeatedly Recurrent Colon Cancer Involving the Appendiceal Orifice after Endoscopic Piecemeal Mucosal Resection: A Case Report

저자 : Masau Sekiguchi , Takahisa Matsuda , Shigeki Sekine , Taku Sakamoto , Takeshi Nakajima , Ryoji Kushima , Takayuki Akasu , Yutaka Saito

발행기관 : 대한소화기학회 간행물 : 대한소화기학회지 61권 5호 발행 연도 : 2013 페이지 : pp. 286-289 (4 pages)

다운로드

(기관인증 필요)

초록보기

Local recurrence after endoscopic piecemeal mucosal resection (EPMR) for colorectal tumors is a crucial issue. However, such recurrence is usually detected within one year and cured with additional endoscopic treatment, which makes EPMR acceptable. Herein, we report a rare case of repeatedly recurrent colon cancer involving the appendiceal orifice after EPMR, which was not cured with additional endoscopic treatments. A 67-year-old man was referred to us for endoscopic treatment of a 25 mm cecal tumor spreading to the appendiceal orifice in May 2002. The tumor was resected with EPMR, showing well differentiated intramucosal adenocarcinoma with a positive lateral cut margin of tubular adenoma. Endoscopic surveillance was conducted and the first local recurrence was detected in August 2006. Although we resected it endoscopically, the second local recurrence was found in September 2007 and we removed it with endoscopic resection again. However, the third local recurrence was detected in March 2008. Although endoscopic resection was performed also for the third recurrence, curative resection was not achieved. In February 2009, laparoscopic assisted colectomy was performed and histopathological examination showed well differentiated adenocarcinoma with deep submucosal invasion. This case is important in considering indication for endoscopic resection in colorectal tumors involving the appendiceal orifice.

10증례 : 상부위장관 출혈을 동반한 담낭-위-대장 누공 1예

저자 : 박민규 ( Min Kyu Park ) , 정윤진 ( Yun Jin Chung ) , 백인엽 ( In Yub Baek ) , 김형석 ( Hyeong Seok Kim ) , 배상수 ( Sang Soo Bae ) , 이수옥 ( Su Ok Lee ) , 이경숙 ( Kyoung Suk Lee ) , 권종규 ( Jong Kyu Kwon )

발행기관 : 대한소화기학회 간행물 : 대한소화기학회지 61권 5호 발행 연도 : 2013 페이지 : pp. 291-294 (4 pages)

다운로드

(기관인증 필요)

초록보기

Biliary enteric fistula is an abnormal pathway often caused by biliary disease. It is difficult to diagnose the disease because patients have nonspecific symptoms. A 67-year-old woman presented with hematemesis and melena. She was diagnosed with Dieulafoy lesion on the gastric antrum and underwent endoscopic hemostasis using hemoclips. Follow-up upper gastrointestinal endoscopy revealed an abnormal opening on a previous treated site that was suggestive of biliary enteric fistula. Abdomen simple X-ray and abdominal dynamic CT scan showed pneumobilia and cholecysto-gastric fistula. The patient had cholecystectomy and wedge resection of the gastric antrum, followed by right extended hemicolectomy because of severe adhesive lesion between the gallbladder and colon. She was diagnosed with cholecysto-gastro-colic fistula postoperatively. We report on this case and give a brief review of the literatures.

12
주제별 간행물
간행물명 수록권호

KCI등재 SCOUPUS

Clinical Endoscopy
53권 4호 ~ 53권 4호

KCI등재 SCOUPUS

Intestinal research (Intest Res)
18권 3호 ~ 18권 3호

KCI등재

Allergy asthma & respiratory disease
8권 3호 ~ 8권 3호

KCI등재 SCI SCOUPUS

Gut and Liver
14권 4호 ~ 14권 4호

KCI등재 SCI SCOUPUS

Gut and Liver
14권 4호 ~ 14권 4호

KCI등재 SCI SCOUPUS

Journal of Neurogastroenterology and Motility
26권 3호 ~ 26권 3호

KCI등재 SCI SCOUPUS

Gut and Liver
14권 4호 ~ 14권 4호

KCI등재 SCI SCOUPUS

Gut and Liver
14권 4호 ~ 14권 4호

KCI등재 SCOUPUS

Clinical and Molecular Hepatology(대한간학회지)
26권 3호 ~ 26권 3호

Korean Journal of Medicine(구 대한내과학회지)
95권 4호 ~ 95권 4호

KCI등재 SCOUPUS

대한소화기학회지
76권 1호 ~ 76권 1호

KCI등재 SCOUPUS

Kidney Research and Clinical Practice(구 대한신장학회지)
39권 2호 ~ 39권 2호

KCI등재 SCOUPUS

Clinical and Molecular Hepatology(대한간학회지)
26권 2호 ~ 26권 2호

KCI등재 SCI

The Korean Journal of Internal Medicine
35권 4호 ~ 35권 4호

당뇨병(JKD)
21권 2호 ~ 21권 2호

KCI등재 SCI SCOUPUS

Diabetes and Metabolism Journal (DMJ)
44권 3호 ~ 44권 3호

KCI등재 SCOUPUS

대한소화기학회지
75권 6호 ~ 75권 6호

KCI등재 SCI SCOUPUS

Endocrinology and Metabolism(구 대한내분비학회지)
35권 2호 ~ 35권 2호

KCI등재 SCOUPUS

Tuberculosis and Respiratory Diseases
83권 3호 ~ 83권 3호

Single Topic Symposium (STS)
2020권 1호 ~ 2020권 1호
발행기관 최신논문
자료제공: 네이버학술정보
발행기관 최신논문
자료제공: 네이버학술정보

내가 찾은 최근 검색어

최근 열람 자료

맞춤 논문

보관함

내 보관함
공유한 보관함

1:1문의

닫기