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대한피부과학회> 대한피부과학회지> 증례 : 위에 발생한 광범위 큰 B세포 림프종과 연관된 한랭글로불린혈증

KCI등재SCOUPUS

증례 : 위에 발생한 광범위 큰 B세포 림프종과 연관된 한랭글로불린혈증

Cryoglobulinemia Associated with Gastric Diffuse Large B Cell Lymphoma

전수영 ( Su Young Jeon ) , 고동엽 ( Dong Yeob Ko ) , 홍진우 ( Jin Woo Hong ) , 이기열 ( Ki Yeol Lee ) , 김기호 ( Ki Ho Kim ) , 송기훈 ( Ki Hoon Song )
  • : 대한피부과학회
  • : 대한피부과학회지 49권12호
  • : 연속간행물
  • : 2011년 12월
  • : 1087-1092(6pages)

DOI


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초록 보기

Cryoglobulinemia, first described by Wintrobe and Buell in 1933, is characterized by the presence of serum immunoglobulins that precipitate below 37oC and that dissolve on rewarming. Although the actual mechanism of cryoprecipitation and the etiology of cryoglobulinemia remains obscure, it is frequently associated with other systemic diseases, such as hepatitis C virus (HCV) infection, multiple myeloma, Sjogren`s syndrome, B cell lymphoma, and systemic lupus erythematosus. No cases of cryoglobulinemia associated with B cell lymphoma have ever been published in the Korean medical literature, and few such cases have been reported in other countries. Herein, we report on a rare and interesting case of cryoglobulinemia developed in a patient with gastric diffuse large B cell lymphoma. (Korean J Dermatol 2011;49(12):1087~1092)

UCI(KEPA)

I410-ECN-0102-2012-510-002618686

간행물정보

  • : 의약학분야  > 피부과학
  • : KCI등재
  • : SCOPUS
  • : 월간
  • : 0494-4739
  • : 2713-7627
  • : 학술지
  • : 연속간행물
  • : 1960-2021
  • : 9497


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1원저 : 각질형성세포와 피지세포 공생배양을 통한 여드름 발생 실험 모델 연구

저자 : 박미경 ( Mi Kyung Park ) , 박귀영 ( Kui Young Park ) , 김범준 ( Beom Joon Kim ) , 김명남 ( Myeung Nam Kim ) , 김정환 ( Jeong Hwan Kim ) , 고현주 ( Hyun Ju Koh ) , 박원석 ( Won Seok Park )

발행기관 : 대한피부과학회 간행물 : 대한피부과학회지 49권 12호 발행 연도 : 2011 페이지 : pp. 1057-1063 (7 pages)

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Background: Acne vulgaris is a chronic inflammatory disease of the pilosebaceous unit. Keratinocytes and sebocytes are the two major cell types involved in the induction of acne within the pilosebaceous unit. Thus, keratinocytes or sebocytes cultured alone may not accurately reflect the physiology of the acne lesion. Objective: The aim of this study was to examine inflammatory cytokine production and neutral lipid content in keratinocyte and sebocyte co-cultures treated with acne etiologic stimulants. Methods: Spontaneously immortalized, non-tumorigenic human HaCaT keratinocytes and immortalized human facial SZ95 sebocytes were seeded in 24-well culture plates (Nunc, Wiesbaden, Germany). Secretion of inflammatory cytokines by each cell type was analyzed by enzyme-linked immunosorbent assay, and neutral lipid production in the cells was measured by Oil Red O staining. Cells were then simultaneously treated with multiple stimulants at various concentrations, and triglyceride and interleukin 8 (IL-8) levels were measured. Results: Arachidonic acid, linoleic acid, dihydrotestosterone and P. acnes extract all induced IL-8 production. De novo synthesis of sebaceous lipids was observed more frequently in the keratinocyte/sebocyte co-culture than that in the sebocyte monoculture. Higher levels of IL-8 were detected in the multi-stimulant system than those in the mono stimulant system. Conclusion: The results suggest that co-culture of keratinocytes and sebocytes is more representative of the clinical condition associated with the development of acne lesions than culture of either cell type alone. The co-culture system used in this study is applicable to research acne vulgaris pathogenesis and to screen active drugs for treating this condition. (Korean J Dermatol 2011;49(12):1057~1063)

2원저 : Methyl Aminolevulinate를 이용한 광역동요법의 결절형 기저세포암에 대한 치료효과

저자 : 송기훈 ( Ki Hoon Song ) , 홍진우 ( Jin Woo Hong ) , 김기호 ( Ki Ho Kim )

발행기관 : 대한피부과학회 간행물 : 대한피부과학회지 49권 12호 발행 연도 : 2011 페이지 : pp. 1064-1072 (9 pages)

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Background: Photodynamic therapy (PDT) is useful for treating basal cell carcinoma (BCC), and the incidence of nodular type BCC is high among Koreans. However, only one case on the treatment of nodular BCC using methyl aminolevulinate (MAL)-PDT has been reported in Korea. Objective: We investigated the efficacy and tolerability of PDT for treating nodular BCC in Korean patients. Methods: Fifteen patients with nodular BCC were treated. We conducted three MAL-PDT sessions separated by a 1 week interval and assessed the clinical therapeutic effects after 3 months. Then, we performed a histopathological assessment of the lesions in patients who showed complete clinical responses (CR) and surgical procedures for lesions in patients who showed no clinical response (NR). We prescribed three more MAL-PDT sessions to the patients who showed partial clinical responses (PR), and decided whether to carry out a histopathological evaluation or to treat with surgery according to the clinical therapeutic assessment after 3 months. Results: After the first three MAL-PDT sessions, three patients showed CR, eight patients showed PR, and four patients showed NR. One of the eight patients, who had been treated repeatedly, showed CR. Conclusion: BCC occurs mainly as the nodular type in Korea, so MAL-PDT may be the main treatment for BCC in Korean patients. However, it could be used as an alternative treatment for selected nodular BCCs when it is difficult to use conventional therapy or when a serious cosmetic defect is expected. (Korean J Dermatol 2011; 49(12):1064~1072)

3원저 : 광주, 전남 지역의 피부 기저세포암과 편평세포암의 통계학적 고찰(2006~2010)

저자 : 김해련 ( Hae Ryun Kim ) , 나찬호 ( Chan Ho Na ) , 신봉석 ( Bong Seok Shin ) , 최규철 ( Kyu Chul Choi ) , 김민성 ( Min Sung Kim )

발행기관 : 대한피부과학회 간행물 : 대한피부과학회지 49권 12호 발행 연도 : 2011 페이지 : pp. 1073-1078 (6 pages)

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Background: The incidence of cutaneous malignant tumors has been continuously increasing worldwide. Objective: The purpose of this study was to analyze recent trends in the incidence of basal cell carcinoma (BCC) and squamous cell carcinoma (SCC) in patients from Gwangju City and Chonnam Province. Methods: We reviewed clinical data and histopathological reports of 82 cases of BCC and 60 cases of SCC in outpatients who had visited the department of dermatology at Chosun University Hospital between 2006 and 2010. Results: The male-female ratio was 0.61:1 in patients with BCC and 0.87:1 in patients with SCC. The most frequent age group was the eighth decade (42% BCC and 67% SCC). Mean patient ages were 65.1 years and 67.8 years, respectively. The most common involved site was the face (90.2% BCC and 78.3% SCC), particularly the cheek. More skin cancers were found on the left than the right side of head and neck area in male automobile drivers only. The most frequent histological BCC subtype was the nodulocystic type (59.7%), followed by the pigmented (12.1%), and adenoid type (9.7%). The most frequent histological pattern of SCC was the well-differentiated type (66.6%). Development of BCC (61.3%) was more frequent than that of SCC in sun-exposed areas. Conclusion: Our data were similar to those previously reported. In our study, no difference in demographic variables such as age, gender or residence were found between patients with BCC and SCC. Additionally, no differences were observed in the incidence of BCC or SCC among the other variables. Further cohort studies that include cumulative lifetime sun exposure and a large sample size are needed. (Korean J Dermatol 2011;49(12):1073~ 1078)

4증례 : 홍반성 천포창

저자 : 윤지미 ( Ji Mi Yoon ) , 김지연 ( Chi Yeon Kim )

발행기관 : 대한피부과학회 간행물 : 대한피부과학회지 49권 12호 발행 연도 : 2011 페이지 : pp. 1079-1082 (4 pages)

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Pemphigus is a group of blistering autoimmune diseases that affect the skin and mucous membranes with autoantibodies against desmoglein. Among the pemphigus subtypes, pemphigus erythematosus is one of the rare lupus-like variant subtypes of pemphigus that shares common clinical and histopathological manifestations with systemic lupus erythematosus. The lesions appear clinically as erythematous erosive patches on the face in a butterfly distribution, and they manifest subcorneal acantholysis histopathologically. There is concomitant basement membrane zone deposition of immunoglobulin and complement in lesional skin in addition to intercellular space staining in the epidermis. Two cases of pemphigus erythematosus have been reported domestically. Here, we report a case of pemphigus erythematosus in an 18-year old woman. (Korean J Dermatol 2011;49(12):1079~1082)

5증례 : 특징적인 Dermoscopy 소견을 보이며 국소 Tacalcitol 치료에 의해 호전된 천공성 광택태선

저자 : 심우행 ( Woo Haing Shim ) , 좌승욱 ( Seung Wook Jwa ) , 송마가렛 ( Mar Ga Ret Song ) , 김훈수 ( Hoon Soo Kim ) , 고현창 ( Hyun Chang Ko ) , 김병수 ( Byung Soo Kim ) , 김문범 ( Moon Bum Kim )

발행기관 : 대한피부과학회 간행물 : 대한피부과학회지 49권 12호 발행 연도 : 2011 페이지 : pp. 1083-1086 (4 pages)

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Perforating lichen nitidus is an unusual variant of lichen nitidus. It is clinically characterized by umbilicated papules and histopathologically characterized by transepidermal elimination of inflammatory debris from granulomatous infiltrates. Most cases of perforating lichen nitidus are treated with topical corticosteroids, but long-term use of topical corticosteroids could provoke several side effects. Herein, we report a case of perforating lichen nitidus treated effectively and safely with topical tacalcitol ointment. We performed a dermoscopic examination for the perforating lichen nitidus lesion and found the characteristic "frogspawn" dermoscopic feature. (Korean J Dermatol 2011;49(12):1083~1086)

6증례 : 위에 발생한 광범위 큰 B세포 림프종과 연관된 한랭글로불린혈증

저자 : 전수영 ( Su Young Jeon ) , 고동엽 ( Dong Yeob Ko ) , 홍진우 ( Jin Woo Hong ) , 이기열 ( Ki Yeol Lee ) , 김기호 ( Ki Ho Kim ) , 송기훈 ( Ki Hoon Song )

발행기관 : 대한피부과학회 간행물 : 대한피부과학회지 49권 12호 발행 연도 : 2011 페이지 : pp. 1087-1092 (6 pages)

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Cryoglobulinemia, first described by Wintrobe and Buell in 1933, is characterized by the presence of serum immunoglobulins that precipitate below 37oC and that dissolve on rewarming. Although the actual mechanism of cryoprecipitation and the etiology of cryoglobulinemia remains obscure, it is frequently associated with other systemic diseases, such as hepatitis C virus (HCV) infection, multiple myeloma, Sjogren`s syndrome, B cell lymphoma, and systemic lupus erythematosus. No cases of cryoglobulinemia associated with B cell lymphoma have ever been published in the Korean medical literature, and few such cases have been reported in other countries. Herein, we report on a rare and interesting case of cryoglobulinemia developed in a patient with gastric diffuse large B cell lymphoma. (Korean J Dermatol 2011;49(12):1087~1092)

7증례 : 피부에 원발성으로 발생한 고립성 섬유종

저자 : 오유진 ( Yu Jin Oh ) , 유박린 ( Bark Lynn Lew ) , 심우영 ( Woo Young Sim )

발행기관 : 대한피부과학회 간행물 : 대한피부과학회지 49권 12호 발행 연도 : 2011 페이지 : pp. 1093-1097 (5 pages)

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A solitary fibrous tumor (SFT) is a relatively uncommon neoplasm that usually occurs in the pleura. However, SFTs are now known to affect various other anatomic sites as well, including rare examples in the skin. Cutaneous SFT is composed of uniformly spindled cells, which is classically described as a patternless feature. This tumor can mimic a variety of benign and malignant mesenchymal neoplasms. The first patient presented with a 3×3 cm sized subcutaneous nodule on the neck. Histopathologically, the biopsy specimen showed proliferation of spindle cells and epitheliod cells. Immunohistochemical stains for CD34, vimentin, bcl-2, and CD99 were strongly expressed. The second patient presented with a 1.5×1 cm sized subcutaneous nodule on the occipital area. The biopsy specimen was histopathologically consistent with SFT. Primary SFT developing on the skin is extremely rare, and only two cases have been reported in the Korean literature. SFT should be distinguished from primary spindle cell neoplasms of the skin. (Korean J Dermatol 2011;49(12):1093~1097)

8증례 : 건강한 환자에서 발생한 대칭성 이중성 대상포진

저자 : 이시현 ( See Hyun Lee ) , 정혜정 ( Hye Jung Jung ) , 박미연 ( Mi Youn Park ) , 안지영 ( Ji Young Ahn )

발행기관 : 대한피부과학회 간행물 : 대한피부과학회지 49권 12호 발행 연도 : 2011 페이지 : pp. 1098-1101 (4 pages)

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Herpes zoster duplex, particularly herpes zoster duplex symmetricus, is a very rare manifestation of herpes zoster that occurs in immunocompetent patients. A 23-year-old Korean man presented with grouped erythematous, ruptured, crusted vesicles on plaques and papules on his forehead and both temporal areas. He had unexplained pain around the cutaneous lesions for the past 2 weeks, and the vesicles developed 1 week ago. A Tzanck smear test of the skin lesion showed multinucleated giant cells. A punch biopsy taken from the vesicle on the forehead revealed an intraepidermal vesicle with acantholysis and balloon cells at the floor of the vesicle. He was diagnosed with herpes zoster involving bilateral dermatomes. (Korean J Dermatol 2011;49(12):1098~1101)

9증례 : 4세 여아의 거대 선천멜라닌세포모반에서 발생한 악성흑색종

저자 : 전재헌 ( Jae Hun Jun ) , 정한진 ( Han Jin Jung ) , 이석종 ( Seok Jong Lee ) , 이원주 ( Weon Ju Lee ) , 김도원 ( Do Won Kim ) , 박진영 ( Jin Young Park ) , 김명화 ( Myung Hwa Kim ) , 박병철 ( Byung Cheol Park )

발행기관 : 대한피부과학회 간행물 : 대한피부과학회지 49권 12호 발행 연도 : 2011 페이지 : pp. 1102-1106 (5 pages)

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Melanoma may arise from a very giant congenital melanocytic nevus even in the first several years of life. Therefore, excision of a giant congenital melanocytic nevus should be considered as early as possible. However considering surgical and anesthetic risks, the surgery can wait until after the first 6 months of life. Unfortunately, surgical treatment does not completely prevent occurrence of melanoma from a giant congenital melanocytic nevus. Besides, several cases of melanoma occurring after blunt trauma or laser therapy have been reported. We report a case of malignant melanoma associated with a giant congenital melanocytic nevus in a 4-year-old female. The malignant melanoma occurred at the boundaries of the previous surgical excision and laser therapy sites for a giant congenital melanocytic nevus. This is the youngest case of malignant melanoma developed from a congenital melanocytic nevus in the Korean dermatological literature. (Korean J Dermatol 2011;49(12):1102~1106)

10증례 : 만성 B형 바이러스 간염과 연관된 범발형 백반증

저자 : 배유인 ( You In Bae ) , 이강모 ( Gang Mo Lee ) , 김정은 ( Jung Eun Kim ) , 이상훈 ( Sang Hoon Lee ) , 이성열 ( Sung Yul Lee ) , 박영립 ( Young Lip Park )

발행기관 : 대한피부과학회 간행물 : 대한피부과학회지 49권 12호 발행 연도 : 2011 페이지 : pp. 1107-1110 (4 pages)

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Vitiligo universalis is an uncommon variant that is rarely seen. Interestingly, vitiligo universalis often accompanies systemic diseases such as endocrinopathies. A 43-year-old man presented with whole body depigmentation and poliosis affecting most of his scalp and body hair. He had undergone a liver transplant 2 years ago due to liver cirrhosis from a chronic hepatitis B infection and has been treated for diabetes mellitus for several years. Histopathology showed no melanocytes and an absence of epidermal pigmentation on the skin. We herein report a rare case of vitiligo universalis associated with chronic viral hepatitis B. (Korean J Dermatol 2011;49(12):1107~ 1110)

12
주제별 간행물
간행물명 수록권호

KCI등재 SCOUPUS

대한피부과학회지
59권 2호 ~ 59권 2호

KCI등재 SCOUPUS

대한피부과학회지
59권 1호 ~ 59권 1호

KCI등재

대한화장품학회지(J. Soc. Cosmet. Scientists Korea)
46권 4호 ~ 46권 4호

KCI등재 SCI SCOUPUS

Annals of Dermatology
33권 1호 ~ 33권 1호

프로그램북(구 초록집)
72권 2호 ~ 72권 2호

KCI등재 SCOUPUS

대한피부과학회지
58권 10호 ~ 58권 10호

KCI등재 SCOUPUS

대한피부과학회지
58권 9호 ~ 58권 9호

KCI등재 SCI SCOUPUS

Annals of Dermatology
32권 6호 ~ 32권 6호

KCI등재 SCI SCOUPUS

Annals of Dermatology
32권 5호 ~ 32권 5호

KCI등재 SCOUPUS

대한피부과학회지
58권 8호 ~ 58권 8호

KCI등재

대한화장품학회지(J. Soc. Cosmet. Scientists Korea)
46권 3호 ~ 46권 3호

KCI등재 SCOUPUS

대한피부과학회지
58권 7호 ~ 58권 7호

KCI등재 SCI SCOUPUS

Annals of Dermatology
32권 4호 ~ 32권 4호

KCI등재 SCOUPUS

대한피부과학회지
58권 6호 ~ 58권 6호

KCI등재

대한화장품학회지(J. Soc. Cosmet. Scientists Korea)
46권 2호 ~ 46권 2호

KCI등재 SCOUPUS

대한피부과학회지
58권 5호 ~ 58권 5호

KCI등재 SCI SCOUPUS

Annals of Dermatology
32권 3호 ~ 32권 3호

KCI등재 SCOUPUS

대한피부과학회지
58권 4호 ~ 58권 4호

KCI등재

대한화장품학회지(J. Soc. Cosmet. Scientists Korea)
46권 1호 ~ 46권 1호

KCI등재 SCOUPUS

대한피부과학회지
58권 3호 ~ 58권 3호
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