논문 상세보기

대한피부과학회> 대한피부과학회지> 골수이형성 증후군 환자에서 발생한 조직구양 Sweet 증후군 1예

KCI등재SCOUPUS

골수이형성 증후군 환자에서 발생한 조직구양 Sweet 증후군 1예

Short Report : A Case of Histiocytoid Sweet`s Syndrome with Myelodysplastic Syndrome

이규엽 ( Kyu Yeop Lee ) , 권연숙 ( Yeon Sook Kwon ) , 김도영 ( Do Young Kim ) , 김세훈 ( Se Hoon Kim ) , 이광길 ( Kwang Gil Lee ) , 방동식 ( Dong Sik Bang )
  • : 대한피부과학회
  • : 대한피부과학회지 45권7호
  • : 연속간행물
  • : 2007년 07월
  • : 754-757(4pages)
피인용수 : 9건

(자료제공: 네이버학술정보)

DOI


목차


					

키워드 보기


초록 보기


						
Sweet`s syndrome is an acute febrile neutrophilic dermatosis that occurs with malignant disease, mainly myeloid hemopathies, in about 20% of cases. When associated with myelodysplasia, clinical and histologic features of Sweet`s syndrome can be atypical; however its significance is still debated. We encountered a case of Sweet`s syndrome associated with myelodysplastic syndrome in a 63-year-old woman. The clinical presentation strongly suggested Sweet`s syndrome but, histopathologic examination showed dense histiocytic infiltration with prominent upper dermal edema and little neutrophil infiltration. In the evaluation for atypical histopathology and laboratory abnormalities, she was diagnosed with myleodysplastic syndrome by peripheral blood smear and bone marrow biopsy. Histiocytoid Sweet`s syndrome is a currently accepted concept and probably has a close relation with underlying myeloid hemopathies. (Korean J Dermatol 2007;45(7):754∼757)

UCI(KEPA)

I410-ECN-0102-2008-510-002841815

간행물정보

  • : 의약학분야  > 피부과학
  • : KCI등재
  • : SCOPUS
  • : 월간
  • : 0494-4739
  • :
  • : 학술지
  • : 연속간행물
  • : 1960-2019
  • : 9233


저작권 안내

한국학술정보㈜의 모든 학술 자료는 각 학회 및 기관과 저작권 계약을 통해 제공하고 있습니다.

이에 본 자료를 상업적 이용, 무단 배포 등 불법적으로 이용할 시에는 저작권법 및 관계법령에 따른 책임을 질 수 있습니다.

발행기관 최신논문
| | | | 다운로드

1원저 : 내인성 피부 노화에 따른 Desmoglein 1과 3의 발현

저자 : 최유원 ( You Won Choi )

발행기관 : 대한피부과학회 간행물 : 대한피부과학회지 45권 7호 발행 연도 : 2007 페이지 : pp. 645-649 (5 pages)

다운로드

(기관인증 필요)

초록보기

Background: Desmogleins are transmembrane glycoproteins of the desmosome which provide mechanical strength to epithelial tissue. Desmogleins have so far, been implicated in several diseases such as pemphigus, striate palmoplantar keratoderma, 4S and squamous cell carcinomas. Skin cancer usually occurs in old age. And there are reports that the expression of desmogleins are increased in squamous cell carcinoma. However the role of desmogleins in skin aging has not yet been reported. Objective: The purpose of this study was to investigate the expression of desmoglein 1 and 3 according to chronologic skin aging. Methods: A total of 6 normal tissue samples from sun-protected skin of different age groups (from 34-year-old to an 84-year-old) and 1 squamous cell carcinoma tissue from a 72-year-old patient were taken. Western blotting and immunohistochemical staining were performed with anti desmoglein 1 and 3 antibodies. The expression of desmoglein 1 and 3 by Western blotting were calculated semiquantitatively by a densitometer. Results: The expression of desmoglein 1 was 0.382 in the 34-year-old, 0.450 in the 45-year-old, 0.369 in the 56-year-old, 0.761 in the 65-year-old, 1.035 in the 77-year-old and 1.329 ODu/mm2 in the 84-year-old. The expression of desmoglein 3 was 0.830 in the 34-year-old, 0.984 in the 45-year-old, 1.029 in the 56-year-old, 1.534 in the 65-year-old, 1.714 in the 77-year-old and 1.878 ODu/mm2 in the 84-year-old. In immunohistochemical staining, the expression of Dsgl increased from the basal layer to the granular layer and Dsg3 was expressed in the basal and suprabasal layers. Conclusion: The expression of desmoglein 1 and 3 were increased according to chronologic skin aging. (Korean J Dermatol 2007;45(7):645~649)

2원저 : 보통 천포창의 세포자멸사 기전에 관한 연구

저자 : 노병화 ( Byoung Hwa Roh ) , 황규왕 ( Kyu Uang Whang ) , 조문균 ( Moon Kyun Cho ) , 박영립 ( Young Lip Park ) , 이종석 ( Jong Suk Lee ) , 이창우 ( Chang Woo Lee )

발행기관 : 대한피부과학회 간행물 : 대한피부과학회지 45권 7호 발행 연도 : 2007 페이지 : pp. 650-658 (9 pages)

다운로드

(기관인증 필요)

초록보기

Background: Pemphigus vulgaris is an autoimmune bullous dermatoses of skin and mucosa characterized by loss of adhesion between keratinocytes, a process known as acantholysis. Apoptosis, programmed cell death, may participate in pathogenesis of intercellular detachment and loss of cell-matrix interaction. Objective: This study was designed to investigate the induction of apoptosis in the pemphigus lesional epidermis and to elucidate the mechanism of apoptosis induced by pemphigus sera. Methods: Hoechst 33342 staining was performed to determine the induction of apoptosis in the pemphigus lesional epidermis. In addition, we used HaCaT cells treated with pemphigus sera and analyzed the expression of caspase-3, caspase-8, caspase-9 and bcl-2, bcl-xL, bax, bak by the RT-PCR method. Results: In Hoechst 33342 staining, typical findings of apoptosis were observed in the pemphigus lesional epidermis showing acantholysis. RT-PCR showed the upregulation of caspase group (caspase-3, caspase-8, caspase-9), the downregulation of antiapoptotic bcl-2 family (bcl-2, bcl-xL) and the upregulation of proapoptotic bcl-2 family (bax, bak). Conclusion: These results suggest that apoptosis may be associated with acantholysis of pemphigus lesional epidermis and may play an important role in the pathogenesis of pemphigus. (Korean J Dermatol 2007;45(7):650∼658)

3원저 : 한국인 색소성 기저세포암의 Dermoscopy 소견

저자 : 좌승욱 ( Seung Wook Jwa ) , 김문범 ( Moon Bum Kim ) , 고현창 ( Hyun Chang Ko ) , 김병수 ( Byung Soo Kim ) , 김성준 ( Sung Jun Kim ) , 오창근 ( Chang Keun Oh ) , 권경술 ( Kyung Sool Kwon )

발행기관 : 대한피부과학회 간행물 : 대한피부과학회지 45권 7호 발행 연도 : 2007 페이지 : pp. 659-665 (7 pages)

다운로드

(기관인증 필요)

초록보기

Background: Pigmented basal cell carcinomas (PBCC) may be confused with melanoma and other benign pigmented skin lesions. Dermoscopy is a noninvasive technique that is known to increase the diagnostic accuracy of benign versus malignant pigmented skin lesions. Menzies et al recently proposed a simple dermoscopic model for the diagnosis of PBCCs. Objective: To demonstrate whether this criteria was adequate for Korean PBCC patients and seek other characteristic dermoscopic findings in Korean PBCCs. Methods: Dermoscopic images of 50 biopsy-proven PBCCs were examined. Results: Negative features such as a pigment network were not observed in all PBCCs. Positive features - ulceration, large blue-gray ovoid nests, multiple blue-gray globules, maple leaf-like areas, spoke wheel areas and arborizing (treelike) telangiectasia were present in 39 (78.0%), 41 (82.0%), 33 (66.0%), 21 (42.0%), 1 (2.0%) and 32 (64.0%) of 50 PBCCs respectively. All PBCCs satisfied the dermoscopic criteria for diagnosis of PBCC suggested by Menzies et al. Other dermoscopic features were as follows; multiple blue-gray dots (28.0%), milia-like cysts (8.0%), granules (6.0%), diffuse blue-white area (6.0%) and hairpin vessels (2%). Forty-four % of lesions had less than 50% pigmentation of the area and 38.0% of lesions had more than 75% pigmentation. Conclusion: The criteria of PBCC proposed by Menzies et al was useful for dermoscopic diagnosis of Korean PBCCs. Ulceration and pigmentary features such as large blue-gray ovoid nests, multiple blue-gray globules, maple leaf-like areas, multiple blue-gray dots, granules and larger pigmented areas were more frequently observed in Korean PBCCs. However, other specific dermoscopic findings for diagnosis of PBCC in Koreans were not present. (Korean J Dermatol 2007;45(7):659∼665)

4원저 : 석회화된 기저세포암의 석회화 관련 인자의 발현

저자 : 도미옥 ( Mi Ok Do ) , 김소영 ( So Young Kim ) , 최유원 ( You Won Choi ) , 명기범 ( Ki Bum Myung ) , 최혜영 ( Hae Young Choi )

발행기관 : 대한피부과학회 간행물 : 대한피부과학회지 45권 7호 발행 연도 : 2007 페이지 : pp. 666-672 (7 pages)

다운로드

(기관인증 필요)

초록보기

Background: Although basal cell carcinoma (BCC) is the most common human skin tumor, with calcification reportedly taking place in about 20% of all BCC cases, the pathogenesis of calcification in BCC has not yet been studied. Objective: The purpose of this study was to evaluate factors related to the pathogenesis of calcification in BCC. Methods: We performed immunohistochemical staining for β-catenin, frizzled-2, BMP-4, osteopontin, osteocalcin, and osteonectin using frozen skin tissue from 15 cases of BCC with calcification and 11 cases of BCC without calcification. Results: The expression of β-catenin showed positive in 14 of the 15 cases in BCC with calcification, but negative in all 11 cases of BCC without calcification. The expression of frizzled-2 was observed in 14 of the 15 cases in BCC with calcification, and in 10 of the 11 cases in BCC without calcification. The difference did not reach statistical significance (p=0.236). The expression of BMP-4 was observed in all 26 samples of BCC, but the intensity of expression did not reach statistical significance between the two groups (p=0.293). Furthermore, osteopontin and osteocalcin showed no statistical significance between two the groups (p=0.567, p=0.401). The expression of osteonectin was observed in all of the BCC cases, and was stronger in BCC with calcification than in BCC without calcification (p=0.042). Conclusion: We suggest that the calcification in BCC might be related to the increase of β-catenin expression and that osteonectin might also influence the process of calcification in BCC. (Korean J Dermatol 2007;45(7):666∼672)

5원저 : 사춘기 및 성인 아토피피부염 환자에서 스탬프형 배지를 이용한 황색 포도알균의 정량적인 배양

저자 : 성현철 ( Hyun Chul Sung ) , 정홍대 ( Hong Dae Jung ) , 박경덕 ( Kyung Duck Park ) , 이원주 ( Weon Ju Lee ) , 이석종 ( Seok Jong Lee ) , 김도원 ( Do Won Kim )

발행기관 : 대한피부과학회 간행물 : 대한피부과학회지 45권 7호 발행 연도 : 2007 페이지 : pp. 673-679 (7 pages)

다운로드

(기관인증 필요)

초록보기

Background: The stratum corneum of the skin of patients with atopic dermatitis (AD) is highly susceptible to colonization by various bacteria, including Staphylococcus (S.) aureus. Because the frequency of bacterial colonization is significantly higher, skin barrier function against bacterial invasion appears to be significantly disrupted in AD. S. aureus colonization in AD is thought to be important in the development and aggravation of eczematous skin lesions. Over the past decades, there have been several quantitative methods of cutaneous bacterial culture from the skin; the swab method, scrub method, tape method and contact plate method. Objective: The purpose of this study was to evaluate the effectiveness of the contact-plate sampling technique as a quantitative culture method of S. aureus in atopic dermatitis. Method: The subjects were 24 patients with AD and 24 age-matched normal controls. S. aureus was sampled at 4 evaluation sites (neck forearm abdomen, popliteal fossa) of AD patients and normal controls using the contact-plate sampling technique. We also checked skin barrier function by measuring the transepidermal water loss (TEWL). Results: Based on the data, we found that the number of S. aureus colonies in the samples from AD patients was significantly higher than from normal controls (p<0.05, 4 sites respectively). Also, TEWL at the 4 evaluation sites of AD patients was significantly higher than in normal controls (p<0.05, 4 sites respectively). However, S. aureus colonization did not usually show significant correlation with TEWL. Conclusion: The contact-plate sampling technique provides a reliable qualitative and quantitative culture method of S. aureus, which is inexpensive and convenient so can be used in both children and within a busy clinic. (Korean J Dermatol 2007;47(7):673∼679)

6원저 : 만성 특발성 두드러기 환자에서 저용량 Cyclosporine 치료 효과에 관한 연구

저자 : 김병수 ( Byung Soo Kim ) , 조현호 ( Hyun Ho Cho ) , 고현창 ( Hyun Chang Ko ) , 김성준 ( Sung Joon Kim ) , 오창근 ( Chang Keun Oh ) , 권경술 ( Kyung Sool Kwon ) , 김문범 ( Moon Bum Kim )

발행기관 : 대한피부과학회 간행물 : 대한피부과학회지 45권 7호 발행 연도 : 2007 페이지 : pp. 680-686 (7 pages)

다운로드

(기관인증 필요)

초록보기

Background: Chronic idiopathic urticaria (CIU) has a major impact on patients` quality of life. However the management of CIU has sometimes been challenging to physicians, with little response to conventional therapy like antihistamines. Objective: This study was aimed to determine the effectiveness and safety of low-dose cyclosporine for the treatment of recalcitrant CIU with a positive autologous serum skin test (ASST). Methods: Thirty CIU patients who were unresponsive to conventional antihistamine therapy were treated for 3 consecutive months with low-dose cyclosporine (2∼3 mg/kg/day) and fexofenadine (180 mg/day). The clinical efficacy was measured at baseline, week 1, 2, and month 1, 2 and 3. CIU sign and symptom scores were assessed using 4-point scales for pruritus, number of hives, size of largest hive, interference with sleep, and interference with daily activities. Global assessment of the severity by patients and any side effects were also measured at every visit. Results: Low-dose cyclosporine significantly improved the total CIU scores. In addition, the interference with sleep was reduced and the performance of daily activities improved in accordance with patient`s global assessment of urticaria severity after 3 month of treatment. Moreover there were no significant side effects to suggest stopping cyclosporine administration. Conclusion: These results show that low-dose cyclosporine therapy might be a good therapeutic alternative in CIU patients who are unresponsive to conventional treatments. (Korean J Dermatol 2007;45(7):680~686)

7증례 : 골수침범을 보인 CD30 양성/ALK 음성 전신성 퇴행성 대세포 림프종 1예

저자 : 이용환 ( Yong Hwan Lee ) , 김수호 ( Soo Ho Kim ) , 서무규 ( Moo Kyu Suh ) , 장태정 ( Tae Jung Jang )

발행기관 : 대한피부과학회 간행물 : 대한피부과학회지 45권 7호 발행 연도 : 2007 페이지 : pp. 687-691 (5 pages)

다운로드

(기관인증 필요)

초록보기

CD 30 positive anaplastic large cell lymphoma (ALCL) is a type of non-Hodgkin`s lymphoma, a tumor that is composed of mostly mast cells expressing CD30 antigens. According to the 2005 World Health Organization-European Organization for Research and Treatment of Cancer (WHO-EORTC) classification, it can be classified as systemic ALCL and primary cutaneous CD30 positive T-cell lymphoproliferative disorder. Systemic ALCL can be subclassified into ALK positive and negative. There have been many cases of primary cutaneous CD30 positive T-cell lymphoproliferative disorder, but reports of systemic ALCL have been rare. We report a case of CD30 positive/ALK negative systemic anaplastic large cell lymphoma involving bone marrow in a 51 year-old-male who showed two pruritic, 1.5×1.0×0.8 cm and 1.0×0.5×0.4 cm sized, erosive, erythematous nodules on the right thigh and calf. (Korean J Dermatol 2007;45(7):687∼691)

8증례 : 지속적 안와 부종 후에 발생한 연부조직염 양상의 비강 CD56 양성 NK/T 세포 림프종 1예

저자 : 김민정 ( Min Jeong Kim ) , 안석용 ( Seok Yong Ahn ) , 구자웅 ( Ja Woong Goo ) , 이원수 ( Won Soo Lee )

발행기관 : 대한피부과학회 간행물 : 대한피부과학회지 45권 7호 발행 연도 : 2007 페이지 : pp. 692-696 (5 pages)

다운로드

(기관인증 필요)

초록보기

Recently another distinct subtype of lymphoma has been discovered, the natural killer (NK)T cell lymphoma, which can involve the skin in a primary or secondary fashion. NK/T cell lymphoma is characterized by the biphenotype expression of the T-cell marker and NK cell marker, especially CD56. These CD56+ lymphomas are further subdivided into nasal NK/T-cell lymphomas and non-nasal NK/T-cell lymphomas. We report a case of primary nasal NK/T cell lymphoma, which showed as an atypical cellulites-like lesion on the face. The patient had suffered with recurrent orbital swelling for several years before diagnosis. (Korean J Dermatol 2007;45(7):692∼696)

9증례 : 류마티스 관절염 환자에서 발생한 울타리모양의 호중구성 육아종성 피부염 1예

저자 : 한예원 ( Ye Won Han ) , 이경호 ( Kyung Ho Lee ) , 이희정 ( Hee Jeong Lee ) , 박철종 ( Chul Jong Park )

발행기관 : 대한피부과학회 간행물 : 대한피부과학회지 45권 7호 발행 연도 : 2007 페이지 : pp. 697-701 (5 pages)

다운로드

(기관인증 필요)

초록보기

Palisaded neutrophilic granulomatous dermatitis (PNGD) is an unusual entity that has been described under several different names including, linear subcutaneous bands, interstitial dermatitis with cutaneous cords and arthritis, rheumatoid papules and Churg-Strauss granuloma. The condition is seen in patients with rheumatoid arthritis and other connective tissue diseases. PNGD shows variable clinical manifestations and represents a histologic spectrum, starting with early vasculitic lesions, then palisaded granulomatous lesions and dermal fibrosis with minimal leukocytoclastic debris in the late stage lesions. We report an unusual case of a 49-year old woman with rheumatoid arthritis who presented with multiple acral nodules. The histologic examination revealed palisaded neutrophilic granulomatous dermatitis. (Korean J Dermatol 2007;45(7):697∼701)

10증례 : B세포 림프종, 식도암, 위암과 동반된 안검외 피지선암 1예 -Muir-Torre 증후군 1 예-

저자 : 이정훈 ( Jeong Hoon Lee ) , 윤숙정 ( Sook Jung Yun ) , 김성진 ( Seong Jin Kim ) , 이승철 ( Seung Chul Lee ) , 원영호 ( Young Ho Won ) , 이지범 ( Jee Bum Lee )

발행기관 : 대한피부과학회 간행물 : 대한피부과학회지 45권 7호 발행 연도 : 2007 페이지 : pp. 702-705 (4 pages)

다운로드

(기관인증 필요)

초록보기

Muir-Torre syndrome (MTS) is a rare autosomal dominant genodermatoses, first described in 1967. It is characterized by the presence of sebaceous tumors and an internal malignancy in the absence of other predisposing factors. The most common internal malignancy associated with MTS is colorectal adenocarcinoma, although a wide tumor spectrum exists including carcinomas of the genitourinary tract, breast, and hematologic malignancy. It is rare for more than two internal malignancies to occur in MTS. We report a rare case of MTS with B-cell lymphoma, esophageal cancer and gastric malignancy in a 63-year-old male. (Korean J Dermatol 2007;45(7):702∼705)

123
주제별 간행물
간행물명 수록권호

KCI등재

대한화장품학회지(J. Soc. Cosmet. Scientists Korea)
45권 3호 ~ 45권 3호

KCI등재 SCOUPUS

대한피부과학회지
57권 8호 ~ 57권 8호

KCI등재 SCI SCOUPUS

Annals of Dermatology
31권 5호 ~ 31권 5호

한국피부장벽학회지
21권 1호 ~ 21권 1호

KCI등재 SCOUPUS

대한피부과학회지
57권 7호 ~ 57권 7호

KCI등재 SCOUPUS

대한피부과학회지
57권 6호 ~ 57권 6호

KCI등재

대한화장품학회지(J. Soc. Cosmet. Scientists Korea)
45권 2호 ~ 45권 2호

KCI등재 SCI SCOUPUS

Annals of Dermatology
31권 44호 ~ 31권 44호

KCI등재 SCI SCOUPUS

Annals of Dermatology
31권 4호 ~ 31권 s4호

KCI등재 SCOUPUS

대한피부과학회지
57권 5호 ~ 57권 5호

KCI등재 SCOUPUS

대한피부과학회지
57권 4호 ~ 57권 4호

프로그램북(구 초록집)
71권 1호 ~ 71권 1호

KCI등재

대한화장품학회지(J. Soc. Cosmet. Scientists Korea)
11권 0호 ~ 26권 2호

KCI등재 SCI SCOUPUS

Annals of Dermatology
31권 3호 ~ 31권 3호

KCI등재

대한화장품학회지(J. Soc. Cosmet. Scientists Korea)
27권 1호 ~ 33권 2호

KCI등재

대한화장품학회지(J. Soc. Cosmet. Scientists Korea)
10권 0호 ~ 8권 0호

KCI등재

대한화장품학회지(J. Soc. Cosmet. Scientists Korea)
33권 3호 ~ 37권 2호

KCI등재

대한화장품학회지(J. Soc. Cosmet. Scientists Korea)
37권 3호 ~ 39권 4호

KCI등재

대한화장품학회지(J. Soc. Cosmet. Scientists Korea)
40권 1호 ~ 42권 4호

KCI등재

대한화장품학회지(J. Soc. Cosmet. Scientists Korea)
1권 0호 ~ 45권 1호
발행기관 최신논문
자료제공: 네이버학술정보
발행기관 최신논문
자료제공: 네이버학술정보

내가 찾은 최근 검색어

최근 열람 자료

맞춤 논문

보관함

내 보관함
공유한 보관함

1:1문의

닫기