폐경여성에 있어서 12예에서 conjegated equine estrogen(0.625mg/dl)과 48예에서 conjegated equine estrogen(0.625mg/dl)과 medroxy progesteron(5mg/dl)을 병행투여하여 다음과 같은 결론 을 얻었다. 1. 혈중 Lipoprotein(a)의 농도는 나이나 폐경기간과는 상관관계가 없었다. 2. 혈중 total cholesterol 은 치료전 216.0+-13.8 mg/dl에서 치료후 198.5+-6.9mg/d로 의의있게 감소하였으며 (p.
Obejctive : To evaluate whether postmenopusal hormone replacement therapy influences the plasma lipoprotein with special emphasis on lipoprotein (a). Methods : 60 postmenopusal women, who visited Yongdong severance hospitial were assesed. After a baseline study, conjugated equine estrogen(0.625mg) was given to 12 women(group A) and conjugated equine estrogen(0.625mg) plus medroxyprogesterone acetate (5mg) were given to 48 women(group B). Blood samples were obtained at 3 months and 5 months after therapy. Ruselts : Serum lipoprotein(a) concentration was not correlated with the age and the duration of menopause. Serum total cholesterol was decreased from 216.0+-13.8 mg/dl to 198.5+-6.9mg/dl at 5 months after therapy (p.