Objectives: The purpose of this study was to analyze domestic qualitative research papers of the Satir Transformational Systemic Therapy and suggest the possibility of applying it to Korean medicine counseling.
Methods: Domestic research papers were gathered by keywords 'Satire Counseling' or 'Satir Transformational Systemic Therapy' and 'Qualitative Research' in RISS (http://www.riss.kr/), KISS (http:// kiss.kstudy.com/), OASIS (http://oasis.kiom.re.kr/). The results were seven papers. Seven papers were selected based on grounded theory and case studies. Researchers analyzed the phenomena during the course of counseling to discuss the mechanism of the Satir Transformational Systemic Therapy and consider its applicability to Korean medicine psychotherapy.
Results: The Satir Transformational Systemic Therapy has three points: 'Self', 'Communication', and 'Family'. Positive changes such as 'Self-recovery', 'Consistent communication', and 'Recovery of relationships' are derived from these three points. And techniques such as iceberg exploration, family maps, three-members in a born family, and the family sculpture are also effective means.
Conclusions: The Satir Transformational Systemic Therapy is valuable in the clinical fields of Korean medicine counseling, especially relative to problems stemming from relationships.

Objectives: The purpose of this study was to research the correlation between academic achievement, lifestyle, and the psychological characteristics of Korean medical students.
Methods: The grade point averages of 73 Korean medical students were collected. Surveys including lifestyle and psychological properties of Korean medical students were conducted.
Results: In the MBI-SS (Maslach Burnout Inventory-Student Survey) survey, the scores of the top, medium, and bottom groups showed statistically significant difference in at least one group, and the score of the bottom group was higher than that of the top group. In the SES (Self-Esteem Scale) survey, the scores of the top, middle, and bottom groups showed statistically significant differences in at least one group, and the scores of the top group were higher than those of the medium and bottom groups.
Conclusions: Some lifestyle and psychological characteristics of Korean medical students were correlated with academic achievement. Thus, the results could be used as a valuable resource for improving academic achievements of Korean medical students.

Objectives: Alzheimer's disease (AD) is a complex disease accompanied by slow impairment of memory and coordination leading to behavioral changes. To date, the only treatment option is to delay the progress of the disease. The purpose of this study was to investigate the synergistic effects of combination treatment with donepezil and three herbal extracts SIP-3 in the AD mouse model induced by amyloid- β (Aβ).
Methods: We tested SIP-3 extracts for the cytotoxicity on Aβ-treated SH-SY5Y cells. Then the synergistic effects of SIP-3 and donepezil were evaluated in the AD mouse model using animal experiments and the next generation sequencing (NGS) study.
Results: We found that co-treatment with SIP-3 extracts and donepezil increased the viability in Aβ- treated SH-SY5Y cells. The beneficial effects of the co-treatment were also observed in the Aβ-induced AD mouse model. The NGS study was performed to show that the co-treatment of SIP-3 and donepezil restored the disease phenotype closely to the normal level in the AD mouse model in terms of mRNA expression. However, the phenotypes were only partially restored.
Conclusions: This study suggests that the combination treatment has a potential to be used for the treatment of AD. However, longer periods of treatment may be required.

Objectives: The purpose of this study was to check the therapeutic effect of the Dendropanax morbifera Pharmacopuncture for insomnia and cognition caused by psychosocial stress.
Methods: We separated Wistar rats (older than age 10 weeks, 300 g) into normal, control, positive control (Zolpidem administered, PC), and Dendropanax morbifera Pharmacopuncture experimental groups (DPA). Psychosocial stress such as circadian rhythm change, clammy straw, predator stress, restraint stress, noise bursts, and flashing lights were applied to the control, PC, DPA groups. The Dendropanax morbifera Pharmacopuncture group was given 0.5×, 1× and 2× amount concentration of Dendropanax morbifera Pharmacopuncture, respectively. The levels of Melatonin, Serotonin, Corticosterone, GABA, BDNF and CREB were measured, and the Y-maze test, weight and blood test were performed.
Results: In all of the DPA groups, the Melatonin level showed no noticeable difference. In the DPA-2x group, Serotonin increased significantly. In all the experimental groups, Corticosterone decreased significantly and GABA showed increasing tendency. The DPA-1x and DPA-2x groups showed remarkable increase in BDNF and DPA-0.5x and the DPA-2x groups showed significant increase in CREB. The DPA-2x group showed remarkable increase in the Alternation behavior category of the Y-maze test. In all of the experimental groups the weight change showed increasing tendency, whereas no noticeable differences were found among all experimental groups regarding AST, ALT, BUN, Creatinine and CBC.
Conclusions: Dendropanax morbifera Pharmacopuncture increases levels of serotonin and GABA, decreases corticosterone, increases levels of BDNF and CREB, and increases the ratio of alternation behavior in the Y-maze test. Thus, I suggest that Dendropanax morbifera Pharmacopuncture has the effect of treating insomnia caused by psychosocial stress, activating the brain, and improving cognition.

Objectives: This study was designed to examine the effect of Hominis Placenta Pharmacopuncture on the change in behavior, sleep-related hormones, inflammatory cytokines, anti-oxidants, weight, blood, and serum on rats given chronic physical stress.
Methods: Wistar rats older than age 10 weeks were used in this experiment. They were divided into six groups. The normal group was not given stress. The control group was given only chronic physical stress and no treatment. The positive control group was given chronic physical stress and treated with zolpidem. Three Hominis Placenta Pharmacopuncture (HPP) groups were given chronic physical stress, then treated with different concentrations of HPP; HPP-0.5× (0.5 times diluted), HPP-1× (undiluted) and HPP-2× (2 times condensed). The changes of values of Nestlet Shredding results, weight, Melatonin, Gamma-aminobutylic Acid (GABA), Tumor Necrosis Factor Alpha (TNF-α), Interleukin-6 (IL-6), Superoxide dismutase (SOD), glutathione peroxidase (GPx), AST, ALT, BUN, Creatinine, and leukocytes were observed during the experiment.
Results: The changes in chronic physical stress of the rat model were as follow. The Nestlet Shredding result increased in the control group compared to the normal group (p<0.05), and decreased in the HPP-1× and HPP-2× compared to the control group (p<0.05). The amount of weight gain showed increasing tendency in the HPP-2× compared to the control group since the second week. The GABA increased (p<0.05) and Melatonin also showed certain increasing tendency in the HPP-1× and HPP-2× compared to the control group. The TNF-α and IL-6 increased in the control group compared to the normal group (p<0.01), and decreased in all the HPPs compared to the control group (p<0.05). The SOD level decreased in the control group compared to the normal group (p<0.01), and increased in all the HPPs compared to the control group (p<0.05). GPx, AST, ALT, Bun, Creatinine and leukocytes showed no noticeable difference among all groups.
Conclusions: Hominis Placenta Pharmacopuncture was effective in increasing weight, GABA, Melatonin, SOD, and decreasing Nestlet Shredding and inflammatory cytokines, suggesting that it consequently facilitates in relieving physical stress.

Objectives: The purpose of this study was to review the research trends in the treatment of tai chi on depression.
Methods: We searched articles in Pubmed and the China National Knowledge Infrastructure (CNKI) July 2009∼June 2019. Selected studies were evaluated by the Jadad scale.
Results: Fifteen controlled clinical trials were selected. The GDS (Geriatric Depression Scale) and SDS (Self-rating Depression Scale) were most frequently used as diagnostic criteria. The GDS was also the most commonly used outcome measurement. From the Jadad scale of 15 articles, the quality of the studies was low, overall.
Conclusions: According to this study, it seems that tai chi treatment for depressive disorder is an effective and safe intervention. Thus, based on this study, more clinical research on diverse forms of treatments for depressive disorder should be performed in Korean medicine in the near future.