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Clinical Nutrition Research update

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수록정보
수록범위 : 1권1호(2012)~9권1호(2020) |수록논문 수 : 223
Clinical Nutrition Research
9권1호(2020년 01월) 수록논문
최근 권호 논문
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KCI등재

1Marine Healing, but Not Additional Intake of Undaria pinnatifida, Benefits Physical and Emotional Exhaustion Symptoms of Menopause

저자 : Hyunju Yun , Bora Lee , Sung Jae Lee , Clara Yongjoo Park

발행기관 : 한국임상영양학회 간행물 : Clinical Nutrition Research 9권 1호 발행 연도 : 2020 페이지 : pp. 1-10 (10 pages)

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Menopausal symptoms can persist or worsen even years after menopause and affect women's quality of life. We investigated whether menopausal symptoms were alleviated through a marine healing program and if sea mustard intake additionally benefits these symptoms. A total of 42 menopausal women self-selected to participate as the marine (n = 22) or city group (n = 20). The marine group participated in a 5-day marine healing program consisting of a balanced diet, exercise, and mind-body practices using ocean resources. The city group continued one's daily routine without any intervention. Within the marine group, participants were randomly assigned to consume sea mustard (Undaria pinnatifida) (15.4 g dry weight/day; n = 11) or control (n = 11). Changes in menopausal symptoms were measured using the Menopause Rating Scale (MRS) before, immediately after, and 2 weeks after the end of the marine healing program. The city group completed the MRS at baseline and on day 20. Within subject differences of menopausal symptoms between baseline and immediately after the marine healing program were assessed using paired t-test. Intervention effects were assessed by mixed analysis of variance. Somatic, psychological, and urogenital symptoms were immediately alleviated after the marine healing program. No effect of sea mustard was detected in the marine group. After 2 weeks, the effect of marine healing persisted in physical and mental exhaustion only. A 5-day integrated marine healing program, but not additional sea mustard intake, temporarily alleviated menopausal symptoms. The reduction in physical and mental exhaustion after marine healing can be maintained for 2 weeks.

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2Effects of Quercetin Supplementation on Hematological Parameters in Non-Alcoholic Fatty Liver Disease: a Randomized, Double-Blind, Placebo-Controlled Pilot Study

저자 : Yahya Pasdar , Farhad Oubari , Mahin Nikougoftar Zarif , Mehrnaz Abbasi , Azizollah Pourmahmoudi , Mahboobe Hosseinikia

발행기관 : 한국임상영양학회 간행물 : Clinical Nutrition Research 9권 1호 발행 연도 : 2020 페이지 : pp. 11-19 (9 pages)

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Non-alcoholic fatty liver disease (NAFLD) is the most common liver disease which has become a public health concern. Since oxidative stress plays a crucial role in the pathogenesis of NAFLD, subsequent hematological disorders are expected. Therefore, antioxidant compounds such as quercetin could ameliorate the related side-effect of oxidative stress. The aim of the current study was to assess the effect of quercetin on hematological parameters in NAFLD patients. A randomized, double-blind, placebo-controlled trial was conducted as a pilot study. In this study 90 patients with NAFLD were supplemented with either a quercetin or a placebo capsule twice daily (500 mg) for 12 weeks. Blood sample was obtained for laboratory parameters at baseline and the end of week 12. End of trial values for red blood cell (RBC; p = 0.002), mean corpuscular hemoglobin concentration (p = 0.029), and mean platelet volume (p = 0.017), significantly increased and the levels of mean corpuscular volume (MCV; p = 0.023), RBC distribution width-coefficient of variation (p = 0.005), platelet distribution width (p = 0.015), and ferritin (p = 0.002) significantly decreased compared to the baseline in group receiving quercetin. Between group analysis revealed that RBC significantly increased (p = 0.025) but, mean corpuscular volume (p = 0.004), mean corpuscular hemoglobin (MCH; p = 0.002), and ferritin (p = 0.013) significantly decreased compared to placebo group. In this work quercetin showed significant effect on RBC, ferritin, MCV, and MCH in intervention group.

KCI등재

3An Empirical Study on the Effect of Short-Term Regular Vitamin D3 Supplement Therapy on Blood Pressure and Exercise Tolerance in Heart Failure Patients

저자 : Fahimeh Hosseinzadeh , Nader Jangi Oskouei , Saeid Ghavamzadeh

발행기관 : 한국임상영양학회 간행물 : Clinical Nutrition Research 9권 1호 발행 연도 : 2020 페이지 : pp. 20-31 (12 pages)

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The receptor of vitamin D is expressed in almost all body cells, including vascular endothelial cells and cardiomyocytes. Vitamin D deficiency has been observed widespread amongst heart failure (HF) patients, which could have harmful effects on their health condition. This study aims to investigate the effect of vitamin D supplements on blood pressure (BP) and physical activity of HF patients. Thirty-nine systolic HF patients with low ejection fraction (EF) < 50% and class III of New York Heart Association functional classification were randomly divided into 2 groups including intervention and placebo to enroll in an 8 weeks double-blind clinical trial. During the trial 6-minute walk test (6MWT), 25-hydroxyvitamin D (25[OH]D) level, BP, sodium and potassium intakes were assessed. The mean 25(OH)D level increased to 28.9 ± 11.7 ng/mL (p < 0.001) in the intervention group. There was a poor but non-significant reduction in systolic BP (-0.033 ± 4.71 mmHg, p = 0.531) in the intervention group. The BP also did not change in the placebo group at the end of the trial. A negligible decrease of 6MWT was observed in the intervention group (-6.6 ± 29.2 m) compared to the placebo (-14.1 ± 40.5 m). However, differences between the 2 groups were not statistically significant (p = 0.325). The results solely showed a slight positive correlation between 25(OH)D level and 6MWT. No significant improvements in BP and 6MWT were observed after vitamin D3 supplementation.

KCI등재

4Biochemical Index, Nutrition Label Use, and Weight Control Behavior in Female Adolescents: Using the 2010 and 2011 Korea National Health and Nutrition Examination Survey

저자 : Mi-ja Choi , Hyun-ju Jo , Mi-kyung Kim

발행기관 : 한국임상영양학회 간행물 : Clinical Nutrition Research 9권 1호 발행 연도 : 2020 페이지 : pp. 32-42 (11 pages)

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This study was conducted to analyze the biochemical index, nutrient intakes, nutrition label use, diet-related factors and weight control behavior of Korean female adolescents at the age of 12 to 18 according to body mass index (BMI) by using the results of the 2010 and 2011 Korea National Health and Nutrition Examination Surveys. The obese group had higher waist circumference (p < 0.001) and systolic blood pressure (p < 0.01) than the normal group. In the biochemical index, the obese group had lower serum high-density lipoprotein-cholesterol level (p < 0.001), while their triglyceride level was higher than the normal group (p < 0.01). Nutrient intake according to BMI was not significantly different except carbohydrate, and calcium intake was about 53% of recommended nutrient intake in all study subjects. The nutrition label was recognized in more than 90% of all groups. But actual nutrition label use was below 50% in all groups and the underweight group was the lowest (p < 0.05). In the result for subjective body image perception, even in the group with normal BMI, 25.3% recognized themselves as obese, and 75.3% said they were trying to lose weight, indicating that many female teens actually think their bodies are obese. In conclusion, obese female adolescents have high systolic blood pressure and serum triglyceride concentrations, which requires obesity prevention education. And a large number of female adolescents with normal BMI thought they were obese and tried to lose weight. Therefore, education on healthy weight and calcium intake is necessary.

KCI등재

5Effect of High β-glucan Barley on Postprandial Blood Glucose and Insulin Levels in Type 2 Diabetic Patients

저자 : Yukie Fuse , Mariko Higa , Naoko Miyashita , Asami Fujitani , Kaoru Yamashita , Takamasa Ichijo , Seiichiro Aoe , Takahisa Hirose

발행기관 : 한국임상영양학회 간행물 : Clinical Nutrition Research 9권 1호 발행 연도 : 2020 페이지 : pp. 43-51 (9 pages)

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The aim of our study was to investigate whether high β-glucan-containing barley (7.2 g per 100 g) improves postprandial plasma glucose levels and suppresses postprandial insulin levels during a meal tolerance test in type 2 diabetic patients. A meal tolerance test (500 kcal) was conducted using two types of test meals: a test meal with white rice (WR) alone (WR diet) and a test meal with WR mixed with 50% barley (BR diet) as staple food. The side dish was the same in the both meals. The changes in plasma glucose and serum C-peptide immunoreactivity (CPR) levels for 180 minutes after ingestion of the test meals were compared. Ten patients with type 2 diabetes (age 52.5 ± 15.1 years, and 7 males and 3 females) were included in this study. The mean HbA1c level and body mass index were 8.8 ± 1.4%, and 29.7 ± 4.5 kg/m2, respectively. Plasma glucose levels after ingestion of the WR diet or BR diet peaked at 60 minutes, which showed no significant differences between the two types of test meals. However, the incremental area under the curve (IAUC) of plasma glucose levels after ingestion of BR diet was significantly lower than that of WR diet. The serum CPR levels at 180 min and their IAUC over 180 minutes after ingestion of BR diet were significantly lower than those of WR diet. Conclusion: Increase in postprandial plasma glucose and insulin levels was suppressed by mixing high-β-glucan barley with WR in type 2 diabetic patients.

KCI등재

6The Association between Maternal Dietary Iron Intake during the First Trimester of Pregnancy with Pregnancy Outcomes and Pregnancy-Related Complications

저자 : Hossein Hajianfar , Khadijeh Abbasi , Leila Azadbakht , Ahmad Esmaeilzadeh , Negar Mollaghasemi , Arman Arab

발행기관 : 한국임상영양학회 간행물 : Clinical Nutrition Research 9권 1호 발행 연도 : 2020 페이지 : pp. 52-62 (11 pages)

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In this study, we investigated the associations of maternal dietary iron intake during the first trimester of pregnancy and pregnancy outcomes and related complications in pregnant women of Isfahan, Iran. In this prospective study, 812 healthy first-trimester singleton pregnant women were selected randomly from 20 various health centers across Isfahan city during 2015-2016. The maternal dietary iron classified into 2 groups, including heme and non-heme iron. Factors including pre-eclampsia, gestational hypertension, gestational diabetes mellitus, intrauterine growth restriction (IUGR), and nausea and vomiting in pregnancy considered as the pregnancy-related complications. Infant's birth weight, birth height, and birth head circumference were also determined as the pregnancy-outcomes. There was a significant association between total iron consumption and infant head circumference (p = 0.01). Total maternal iron (the sum of heme and non-heme iron) was negatively associated with both infant's birth height (p = 0.006) and birth weight (p = 0.02). Non-heme iron consumption is positively associated with high-risk of IUGR (p = 0.004). Heme intake was associated with an increased risk of maternal fasting blood sugar (FBS) (p = 0.04). Higher heme, non-heme, and total iron intake were associated with lower risk of pre-eclampsia (heme: crude p = 0.05; non-heme iron: adjusted p = 0.02; total iron: adjusted p = 0.05). Maternal total iron intake was directly associated with infant head circumference, whereas, negatively associated with both birth weight and birth height. High non-heme iron intake may increase the risk of IUGR, and a high intake of heme iron may increase FBS.

KCI등재

7A Comparative Study of the Effect of Flaxseed Oil and Sunflower Oil on the Coagulation Score, Selected Oxidative and Inflammatory Parameters in Metabolic Syndrome Patients

저자 : Atefeh Akrami , Elham Makiabadi , Moein Askarpour , Katayoun Zamani , Amir Hadi , Amin Mokari-yamchi , Siavash Babajafari , Shiva Faghih , Abdollah Hojhabrimanesh

발행기관 : 한국임상영양학회 간행물 : Clinical Nutrition Research 9권 1호 발행 연도 : 2020 페이지 : pp. 63-72 (10 pages)

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Metabolic syndrome (MetS) is a chronic disease with inflammatory and hypercoagulable states. The current study aimed to compare the effects of flaxseed oil and sunflower oil consumption on the coagulation score and selected oxidative and inflammatory parameters in patients with MetS. In this randomized controlled clinical trial, 60 patients with MetS were allocated into 2 groups. One group received 25 mL/day flaxseed oil and the other group received 25 mL/day sunflower oil for 7 weeks. Maintenance diet including 15% protein, 55% carbohydrate, and 30% fat from daily total energy intake was designed for each participant. Serum levels of total antioxidant capacity (TAC) and interleukin 6 (IL-6), as well as coagulation score were measured before and after the intervention. Three 24-hour food records were taken during the study. Fifty-two of participants (27 in sunflower oil and 25 in flaxseed oil groups) completed the study. The baseline characteristics and dietary intakes were similar between patients. After 7 weeks, no significant difference was observed between the 2 groups regarding the serum TAC level and coagulation score (p > 0.05). However, serum IL-6 levels significantly decreased in the flaxseed oil group compared to the sunflower oil group (p = 0.017). No side effect was observed during the study due to the use of sunflower and flaxseed oils. We observed that consumption of flaxseed oil improved serum IL-6 levels but had no effect on oxidative stress and coagulation score in patients with MetS. Further studies are needed to confirm the veracity of our results.

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8Using a Mobile-based Nutritional Intervention Application Improves Glycemic Control but Reduces the Intake of Some Nutrients in Patients with Gestational Diabetes Mellitus: A Case Series Study

저자 : Yeonkyung Seo , Eun Mi Kim , Jin Sun Choi , Cheol-young Park

발행기관 : 한국임상영양학회 간행물 : Clinical Nutrition Research 9권 1호 발행 연도 : 2020 페이지 : pp. 73-79 (7 pages)

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The prevalence of gestational diabetes mellitus (GDM) has been increasing worldwide, as has the economic cost associated with this condition. GDM threatens the health of the mother and child, and thus proper monitoring and management are essential. Mobile healthcare services have been applied to manage some diseases, particularly chronic diseases. We aimed to evaluate the utility of a mobile application in nutritional intervention by observing cases of a mobile application in a series of patients with GDM. We provided a mobile-based intervention to GDM patients and collected biochemical and nutritional information. The mobile-based nutritional intervention was effective in controlling carbohydrate intake and improving blood glucose level for patients with GDM.

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