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Journal of Menopausal Medicine

  • : 대한폐경학회
  • : 의약학분야  >  산부인과학
  • : KCI등재
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  • : 2288-6478
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수록정보
수록범위 : 1권1호(1995)~25권1호(2019) |수록논문 수 : 561
대한폐경학회지
25권1호(2019년 04월) 수록논문
최근 권호 논문
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1Foeniculum vulgare as Valuable Plant in Management of Women's Health

저자 : Mohaddese Mahboubi

발행기관 : 대한폐경학회 간행물 : 대한폐경학회지 25권 1호 발행 연도 : 2019 페이지 : pp. 1-14 (14 pages)

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This review paper evaluates use of Foeniculum vulgare extracts as a popular female plant in management of different ailments of women. Information in this paper was gathered from accessible sources (PubMed, Science Direct, Springer, Wiley, and Google), and traditional books (Persian or English modern traditional books), unpublished data (R&D reports, thesis and dissertation) by keywords based on the words F. vulgare or fennel and women. Efficacy of oral fennel oil in management of dysmenorrhea, premenstrual syndrome, amenorrhea, menopause, lactation, and polycystic ovary syndrome were confirmed according to results of clinical studies. Results of clinical efficacy of fennel oil on menstrual bleeding is complicated, but results of one meta-analysis study revealed that fennel oil significantly increased means of bleeding in the first menstrual periodic cycle (P = 0.001), while fennel oil had no significant effect on bleeding in the second menstrual cycle (P = 0.67). Topical and vaginal fennel extract (5%) exhibited good efficacy in treatment of sexual function, vaginal atrophy, and hirsutism. Fennel had no effect on bone density, or body mass index of menopause women. Results of clinical studies introduce fennel as a valuable medicinal plant in management of women's ailments, but understanding the mechanism of action could be the subject of future studies. (J Menopausal Med 2019;25:1-14)

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2Sexual Function and Factors Affecting Menopause: A Systematic Review

저자 : Mohammad Heidari , Mansureh Ghodusi , Parvin Rezaei , Shokouh Kabirian Abyaneh , Ehsan Heidari Sureshjani , Rahim Ali Sheikhi

발행기관 : 대한폐경학회 간행물 : 대한폐경학회지 25권 1호 발행 연도 : 2019 페이지 : pp. 15-27 (13 pages)

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The purpose of this review study is to evaluate sexual function and its effective factors in menopause. A systematic review was conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. The key words of “menopause,” “postmenopause,” “postmenopausal,” “premenopause,” “pre-menopausal period,” “sexual function,” “sexual health,” “sexuality,” “sexual and gender disorders,” “sexual development,” “sexual dysfunction,” “sexual disorders,“ “sexual behavior and “sexual activity” were used in combination with the Boolean operators OR and AND. After reviewing the selected articles, 27 papers were selected based on the criteria for entering the study and the goals set. The results of the reviewed articles showed that, in the physical domain, the factors affecting sexual function can be mentioned, age, hormonal changes, medical problems and reproductive history. Sexual disorders in menopause can be affected by some of the individual and social characteristics and psychological problems. Considering the fact that many psychological and social injuries occur in this period following sexual disorders; therefore, policies and programs for improving the quality of life of women in menopause should be aimed at eliminating sexual dysfunction, correcting attitudes and negative emotions and help to women for more comfortable in menopause. (J Menopausal Med 2019;25:15-27)

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3Comparing Quality of Life of Elderly Menopause Living in Urban and Rural Areas

저자 : Mohammad Heidari , Rahim Ali Sheikhi , Parvin Rezaei , Shokouh Kabirian Abyaneh

발행기관 : 대한폐경학회 간행물 : 대한폐경학회지 25권 1호 발행 연도 : 2019 페이지 : pp. 28-34 (7 pages)

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Objectives: The present study aimed to compare the quality of life of elderly menopause living in urban/rural areas of Abadeh, Iran.
Methods: This descriptive and cross-sectional study was conducted on 312 urban and 68 rural elderly population using the two-stage (systematic random classification) and objective-based sampling methods. Data were collected by Leiden-Padua questionnaire for assessment of quality of life in elderly menopause. SPSS software (version 21) and descriptive-analytical tests were used for data analysis.
Results: The results showed that the overall quality of life was 37.5 and 34.2 in rural and urban areas, respectively, and no statistically significant difference was observed between them. However, there was statistically significant difference in the mean score of depression and anxiety, cognitive function, social function, life satisfaction, and sexual activity in urban and rural elderly menopause (P < 0.001).
Conclusions: It seems necessary to pay more attention to the elderly menopause to improve their quality of life and consider proper planning for their empowerment and coping skills training. (J Menopausal Med 2019;25:28-34)

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4Predictors of Quality of Life in Infertile Couples

저자 : Zahra Royani , Mohammad Heidari , Mahboubeh Vatanparast , Farideh Yaghmaei , Athareh Kalantari Sarcheshme , Jamileh Khademi Majomerd

발행기관 : 대한폐경학회 간행물 : 대한폐경학회지 25권 1호 발행 연도 : 2019 페이지 : pp. 35-40 (6 pages)

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Objectives: This study was conducted with the aim of examines the quality of life of infertile couples and their relationship with the practical resilience of infertile couples referring to Yazd's centers of infertility.
Methods: This research is a descriptive-correlational study. The research population consisted of all infertile couples who referred to Infertility Centers in Yazd, Iran in the winter of 2016. Sampling was conducted in a non-random and accessible manner. The instrument used in the research included a) demographic information questionnaire, b) Conner and Davidson's Resilience Scale, and c) quality of life infertile couples questionnaire. Data were analyzed by SPSS software version 17 at a significant level of P < 0.05. To describe the data, descriptive statistics methods were used and the inferential statistics (Pearson correlation coefficient, regression, independent t test, and variance analysis) were used to test the research hypotheses.
Results: People (202 couples) participated in this research. Three variables of resilience (β = 0.04, P = 0.04), gender (β = -0.22, P < 0.001), and education level (β = 0.21, P < 0.001) had a prediction coefficient and there was a significant relationship with quality of life.
Conclusions: This study showed that resilience, gender, and education predict the quality of life of infertile couples. In the infertile couples counseling program, resilience should be considered as a coping factor. (J Menopausal Med 2019;25:35-40)

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5Breast Cancer Screening Practice and Associated Factors in Menopausal and Postmenopausal Women

저자 : Florence Mei Fung Wong , Winnie Lai Sheung Cheng

발행기관 : 대한폐경학회 간행물 : 대한폐경학회지 25권 1호 발행 연도 : 2019 페이지 : pp. 41-48 (8 pages)

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Objectives: This study examined breast cancer screening (BCS) practices and its associated factors among menopausal and postmenopausal women.
Methods: A cross-sectional design was conducted using convenience sampling at a community center. The modified Chinese BCS Belief questionnaire was used to understand BCS practice.
Results: A total of 144 eligible women presented better knowledge and perceptions about breast cancer (mean, 11.46; standard deviation [SD], 3.65) and barriers to achieving mammographic screening (mean, 14.75; SD, 3.70). Participants aged ≥ 50 years had a negative association with the attitudes towards general health check-ups (B = -1.304, standard error [SE] = 0.65, P = 0.046). In this context, having regular physical exercise had a positive association with attitudes towards general health check ups (B = 1.458, SE = 0.06, P = 0.017), and knowledge and perceptions about breast cancer (B = 1.068, SE = 0.62, P = 0.086). Being employed had a positive associated with barriers to achieving mammographic screening (B = 1.823, SE = 0.51, P < 0.001).
Conclusions: The women had better knowledge and perception about breast cancer and fewer barriers to mammographic screening. However, attitudes towards general health check-ups were relatively poor. It is noteworthy that women who aged ≥ 50 years and had insufficient physical exercise had poor attitudes. Those who were employed had fewer barriers, and those who had regular physical exercise had better knowledge on the benefits of the BCS practice. Importantly, women who aged ≥ 50 years and lack physical exercise need education about breast cancer to increase their awareness of breast wellness. (J Menopausal Med 2019;25:41- 48)

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6The Effects of Menopausal Hormone Therapy on Serum Level of C-reactive Protein in Postmenopausal Korean Women

저자 : Whan Shin , Sung Eun Kim , Jee-yeon Lee , Jong-wook Seo , Hye Sun Hyun , Ji Hyun Suh , Dooseok Choi , Byung-koo Yoon

발행기관 : 대한폐경학회 간행물 : 대한폐경학회지 25권 1호 발행 연도 : 2019 페이지 : pp. 49-54 (6 pages)

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Objectives: Inflammation is a major mechanism underlying coronary heart disease (CHD) and C-reactive protein (CRP) is a marker of inflammation. When administered soon after menopause, menopausal hormone therapy (MHT) prevents CHD. This study was conducted to examine the impact of estrogen by administration route on CRP in postmenopausal Korean women using micronized progesterone (MP4) for endometrial protection.
Methods: This retrospective cohort study included 129 healthy women without CHD risk factors. Eighty-nine women took oral estrogen (conjugated equine estrogen, 0.625 mg/day or equivalent), and 40 women applied a 1.5-mg/day 0.1% percutaneous estradiol gel. MP4 was added in 82 women with an intact uterus. The CRP level was measured at baseline and three and six months after initiation of MHT.
Results: The baseline characteristics were comparable between the MHT groups except current age and age at menopause. After controlling for age, menopausal age, body mass index, and basal CRP, no significant change in CRP was observed in the oral estrogen group (n = 29). Follow-up CRP levels were also similar to the baseline in the percutaneous estrogen group (n = 18). However, three-month CRP was significantly lower than six-month CRP, and there was a significant time trend within the percutaneous estrogen group. However, the group difference did not reach statistical significance. CRP also did not differ by addition of MP4 in either group.
Conclusions: In postmenopausal Korean women, no change in CRP was observed with oral estrogen, while percutaneous estrogen might decrease CRP. The estrogenic impacts were not influenced by adding MP4. (J Menopausal Med 2019;25:49-54)

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7The Efficacy of Body Mass Index and Total Body Fat Percent in Diagnosis Obesity according to Menopausal Status

저자 : Hyekyung Noh , Hyunjoo Lee , Seungchul Kim , Jongkil Joo , Dongsoo Suh , Kihyung Kim , Kyusup Lee

발행기관 : 대한폐경학회 간행물 : 대한폐경학회지 25권 1호 발행 연도 : 2019 페이지 : pp. 55-62 (8 pages)

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Objectives: Body mass index (BMI) is commonly used in epidemiological study or clinical center. However, it is not exactly correlated with body fat composition and does not reflect sex, age, or race. The aim of this article is to evaluate the validity of BMI standards relative to total body fat (TBF) and to estimate new BMI criteria that correspond to TBF for obesity, especially for Asian postmenopausal women.
Methods: A total 3,936 patients were included in this cross-sectional study, including 1,565 premenopausal and 2,371 postmenopausal women. At the time of visit, demographic data were collected. We demonstrated the validity of BMI cut-point of 25 kg/m2 by using area under the curve (AUC), and presented the empirical optimal BMI cut-point by using Youden's index and overall accuracy in both premenopausal and postmenopausal women.
Results: BMI-defined obesity (≥ 25 kg/m2) represents high AUC values (> 0.9) for each TBF. In premenopausal women, TBF ≥ 38% and corresponding BMI value was 29.45 kg/m2 indicated the highest both Youden's index and overall accuracy. In comparison, postmenopausal women who were TBF ≥ 38% showed the highest Youden's index and overall accuracy, and corresponding BMI value was 26.45 kg/m2.
Conclusions: We proposed new BMI criteria for obesity by using TBF reference. With application of bioelectrical impedance analysis, the diagnosis of obesity using BMI criteria may differ between premenopausal and postmenopausal women. (J Menopausal Med 2019;25:55-62)

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8Zinc-containing Vaginal Moisturizer Gel Improves Postmenopausal Vulvovaginal Symptoms: A Pilot Study

저자 : Peter Takacs , Bence Kozma , Balazs Erdodi , Attila Jakab , Kindra Larson , Robert Poka

발행기관 : 대한폐경학회 간행물 : 대한폐경학회지 25권 1호 발행 연도 : 2019 페이지 : pp. 63-68 (6 pages)

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Objectives: Although vaginal estrogen is highly effective in alleviating genitourinary symptoms of menopause (GSM), some women are reluctant to use hormonal treatment. Our aim was to evaluate the effect of a zinc-containing vaginal moisturizer gel on GSM.
Methods: Women with GSM were enrolled. Patients were asked to use the vaginal gel daily for 2 weeks. Vaginal Health Index (VHI) was calculated. Visual analogue scale (VAS) was obtained on vaginal pain, dryness, burning, itching, dyspareunia and dysuria before and 2 weeks after the completion of treatment. Vaginal cytology was obtained. Vulvovaginal symptom questionnaire (VSQ- 21) was used to assess subjective symptoms.
Results: Thirty-seven women with GSM participated in the study. The VHI improved significantly (mean ± standard deviation, 13 ± 4 before vs. 17 ± 4 after treatment, P < 0.01). The patient reported VAS combined score was significantly lower after the treatment (18 ± 14 before vs. 7 ± 12 after treatment, P < 0.01). The largest improvement occurred in vaginal dryness. The maturation value did not change significantly. There were no signs of inflammation on vaginal cytology. VSQ-21 combined scores also improved significantly (7.9 ± 5.5 before vs. 2.7 ± 3.6 after the intervention, P < 0.01). Side effects were rare and minor.
Conclusions: Novel zinc-containing vaginal moisturizer gel significantly improves postmenopausal vulvovaginal symptoms without serious side effects. (J Menopausal Med 2019;25:63-68)

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