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대한피부과학회지 update

Korean Journal of Dermatology

  • : 대한피부과학회
  • : 의약학분야  >  피부과학
  • : KCI등재
  • : SCOPUS
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수록정보
수록범위 : 1권1호(1960)~57권10호(2019) |수록논문 수 : 9,274
대한피부과학회지
57권10호(2019년 12월) 수록논문
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KCI등재 SCOPUS

1피부과로 의뢰된 감염 내과 입원 환자에 대한 임상 양상 분석

저자 : 홍승기 ( Seung Gi Hong ) , 이현주 ( Hyun Joo Lee ) , 허은필 ( Eun Phil Heo ) , 고재완 ( Jae Wan Go )

발행기관 : 대한피부과학회 간행물 : 대한피부과학회지 57권 10호 발행 연도 : 2019 페이지 : pp. 581-586 (6 pages)

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Background: Inpatient dermatological consultations are getting more important and, therefore, several studies of dermatologic consultation from various inpatient departments have recently been reported. However, data regarding the analyses of these consultations for infectious diseases inpatients are limited. Objective: The purpose of this study was to analyze and quantify the patterns of dermatologic consultations referred by the Division of Infectious Diseases.
Methods: We retrospectively reviewed 149 consultation reports for inpatients referred by the Division of Infectious Diseases from January 2014 to May 2019. We analyzed the medical records and noted age, sex, reasons for dermatologic consultation, diagnosis of the dermatoses, and change in diagnosis after the consultation in a single secondary referral center.
Results: The percentage of patients who were referred by the Division of Infectious Diseases and consulted by the Department of Dermatology was 13.2%. The most frequent age group was the 7th decade of life (24.8%) and the male to female ratio was 1:1.04. The main reasons for dermatologic consultations were dermatologic disease not related to underlying infectious disease (43.0%), dermatologic disease related to underlying infectious disease (24.2%), and skin lesions related to the treatment (18.1%). The most common dermatoses were infectious disease (40.3%), followed by eczema (22.1%), and drug eruption, erythema and urticaria (19.5%). There were 10 cases in which the diagnosis of undetermined dermatoses was changed after dermatologic consultation.
Conclusion: This study revealed the distribution of skin disorders inpatients referred by the Division of Infectious Diseases for dermatologic consultation. In conclusion, dermatologists should take an active role in dermatologic consultations for more accurate examinations and treatment of infectious diseases patients. (Korean J Dermatol 2019;57(10):581∼586)

KCI등재 SCOPUS

2집게손발톱에서 탄산가스 프락셔널 레이저와 국소 도포제 병합 치료 연구

저자 : 김예은 ( Ye Eun Kim ) , 조의현 ( Ui Hyeon Jo ) , 박현선 ( Hyunsun Park )

발행기관 : 대한피부과학회 간행물 : 대한피부과학회지 57권 10호 발행 연도 : 2019 페이지 : pp. 587-593 (7 pages)

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Background: Pincer nail is a deformity of the nail that is characterized by the transverse overcurvature of the nail plate. Both conservative and surgical treatments can be used to treat pincer nail. However, there are no reports regarding non-surgical, laser treatment of pincer nail. Objective: To evaluate the treatment outcomes and adverse events of CO2 fractional laser and topical agent combination therapy on pincer nail.
Methods: Eleven pincer nails (all great toenails) were treated with a CO2 fractional laser. An antifungal agent (in case of co-existing onychomycosis) or 20% urea cream was applied to the toenails. The effect of the treatment was measured by evaluating the difference in the width index, height index, and nail angle before and after treatment. Changes in pain levels were also evaluated. All adverse events and recurrences were observed until the last follow-up visit.
Results: The mean number of laser treatments was 2.27 and the mean follow-up period was 18.36 weeks after the last treatment. All 3 measured indices changed significantly after the treatment. The width index increased by 0.16 (p=0.0016), the height index decreased by 1.89 (p=0.008), and the nail angle increased by 29.60° (p=0.005). The pain was reduced in all cases. There were no serious adverse events.
Conclusion: The combination of CO2 fractional laser therapy and topical application is an effective and tolerable treatment for pincer nail. Larger studies with long-term observations are needed to confirm this result. (Korean J Dermatol 2019;57(10):587∼593)

KCI등재 SCOPUS

3아토피 피부염에서 강화 삼산 온천수 보조치료의 효과 및 안전성에 대한 연구

저자 : 신지연 ( Ji Yeoun Shin ) , 홍규락 ( Kyu Rak Hong ) , 권륭 ( Ryung Kwon ) , 김예슬 ( Ye Seul Kim ) , 이설희 ( Sul Hee Lee ) , 박영립 ( Young Lip Park ) , 이상훈 ( Sang Hoon Lee )

발행기관 : 대한피부과학회 간행물 : 대한피부과학회지 57권 10호 발행 연도 : 2019 페이지 : pp. 594-599 (6 pages)

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Background: Atopic dermatitis is a chronic inflammatory disease associated with long-term use of topical and systemic medications. Several articles have described the use of balneotherapy as an adjuvant treatment for atopic dermatitis in many countries, including Korea. Objective: The goal of this study was to investigate the therapeutic efficacy and safety of balneotherapy as an adjuvant treatment of atopic dermatitis.
Methods: Ten patients with atopic dermatitis were enrolled in this study and each patient served as their own control. Testing was conducted on the anterior cubital fossa of the arm. A priori binary randomization was completed to determine which arm would receive balneotherapy or tap water. Patients visited clinics 3 times per week for 2 weeks and had a forearm bath for 15 minutes. Assessment was performed at baseline, and after 1 and 2 weeks of treatment.
Results: At the last visit, the balneotherapy group showed improvements in their local eczema area, severity index score, and the degree transepidermal water loss. The physician's global assessment, patient's self-global assessment, and skin hydration was increased in both groups.
Conclusion: Our study suggests that balneotherapy is a safe adjuvant therapy that could be considered for the treatment of atopic dermatitis. However, more studies are required to demonstrate scientific basis for this treatment. (Korean J Dermatol 2019;57(10):594∼599)

KCI등재 SCOPUS

4소아 발모벽에서 N-acetylcysteine 치료효과에 대한 임상적 고찰

저자 : 김충재 ( Choong Jae Kim ) , 최훈 ( Hoon Choi ) , 나찬호 ( Chan Ho Na ) , 신봉석 ( Bong Seok Shin ) , 김민성 ( Min Sung Kim )

발행기관 : 대한피부과학회 간행물 : 대한피부과학회지 57권 10호 발행 연도 : 2019 페이지 : pp. 600-607 (8 pages)

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Background: Trichotillomania (TTM) is a medical condition that involves recurrent and irresistible urges to pull out their own hair. TTM generally follows a chronic course in most patients and is difficult to treat and manage. Recently, N-acetylcysteine (NAC) has shown efficacy in the treatment of TTM. Objective: The purpose of this study was to assess the efficacy of treatment with NAC in trichotillomania children younger than 13 years of age.
Methods: We evaluated 15 patients under 13 years old who visited the Department of Dermatology at Chosun University Hospital between 2014 and 2019 for TTM. An initial dose of 400-mg NAC was administered to patients under 8 years and 800 mg to patients older than 8 years old. If there was no improvement for 2 weeks, the dose was increased with the maximum daily being 2,400 mg.
Results: The mean age of patients was 10.7 years; 8 were boys and 7 were girls. They presented with several asymptomatic focal patches of hair loss with different hair lengths on scalp. The dermoscopic findings were broken hairs, v-sign hairs, coiled hairs, and focal erythema. 10 out of 15 patients had a good response to NAC, whereas 5 patients did not respond to the treatment. The differences between the 2 groups were the treatment duration and total NAC doses. The effective group had a mean NAC of 973 mg/day for 11.5 weeks, while the non-effective group had a 1060 mg/day dose for 4 weeks.
Conclusion: NAC could be an effective and safe treatment option for TTM in children. (Korean J Dermatol 2019;57(10):600∼607)

KCI등재 SCOPUS

5Characteristics and Management of Cyclosporine-associated Adverse Gastrointestinal Events

저자 : Won Seon Koh , Young Wook Ko , Jeong Eun Kim , Joo Yeon Ko , Young Suck Ro

발행기관 : 대한피부과학회 간행물 : 대한피부과학회지 57권 10호 발행 연도 : 2019 페이지 : pp. 608-616 (9 pages)

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Background: Cyclosporine (CS) is widely used to treat various skin diseases. Gastrointestinal (GI) discomfort is the most common adverse effect of orally administered CS for dermatologic indications. However, few studies on CSassociated adverse GI events have been conducted. Objective: In this study, we aimed to describe the major features of adverse GI events associated with CS therapy using a validated symptom questionnaire, and to investigate the factors contributing to their development. We also evaluated the effectiveness of three empirical GI medications in relieving adverse GI events.
Methods: This study consisted of 2 phases. Phase I was a prospective observational cohort study to investigate the characteristics of CS-associated adverse GI events in 942 consecutive patients treated with CS. Phase II was a randomized controlled trial to evaluate the efficacy of three different classes of GI medications.
Results: CS-associated adverse GI events occurred in 119 patients (12.6%). GI complications were more common in female patients (p=0.04), patients with a history of GI disorders (p=0.02), and patients whose initial CS doses were greater than 3 mg/kg/day (p=0.05). In patients treated with any one of the three GI medications, the mean Gastrointestinal Symptom Rating Scale scores significantly decreased (p<0.001).
Conclusion: This study demonstrated that adverse GI events are common during early CS treatment, especially in women, patients receiving high doses of CS, and those with a history of GI disorders. Our results suggest that new-onset CS-associated GI side effects can be effectively managed with the addition of GI medications. (Korean J Dermatol 2019;57(10):608∼616)

KCI등재 SCOPUS

6조갑 전체를 덮는 드문 양상의 후천성 조갑 주위 섬유각화종 1예

저자 : 류재연 ( Jae Yeon Ryu ) , 박철종 ( Chul Jong Park ) , 이경호 ( Kyung Ho Lee )

발행기관 : 대한피부과학회 간행물 : 대한피부과학회지 57권 10호 발행 연도 : 2019 페이지 : pp. 617-620 (4 pages)

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Acquired periungual fibrokeratoma, first reported by Cahn in 1977, is a rare, benign fibrous tissue tumor located in the periungual area. The pathophysiology of acquired periungual fibrokeratoma is unknown. In general, trauma is often thought to be a predisposing factor. A 57-year-old woman presented with a 15-year-old asymptomatic, solitary, 1.8×1.5-cm, skin-colored mass on the Lt. thumb nail. The patient reported that they had been wounded on the nail root and the mass had since grown. For differential diagnosis and to determine the extent of the tumor, MRI of the finger was performed. Radiologic presentation showed a non-enhancing T2 low, T1 low signal mass above the nail plate. Histopathologic examination demonstrated a dome-shaped tumor consisting of thick dermal collagen bundles with increased capillaries. Through clinical, radiological, and histopathologic findings, we diagnosed the tumor as acquired periungual fibrokeratoma, and the lesion was removed through complete excision. Herein, we present a rare case of acquired fibrokeratoma covering whole thumb. The specific diagnosis was aided by MRI more through the acquisition of more accurate information about the location and signal characteristics that reflect underlying pathological features. (Korean J Dermatol 2019;57(10):617∼620)

KCI등재 SCOPUS

7치은 농양 기원의 피부누공 2예

저자 : 김민성 ( Min Sung Kim ) , 김충재 ( Choong Jae Kim ) , 최훈 ( Hoon Choi ) , 나찬호 ( Chan Ho Na ) , 신봉석 ( Bong Seok Shin )

발행기관 : 대한피부과학회 간행물 : 대한피부과학회지 57권 10호 발행 연도 : 2019 페이지 : pp. 621-625 (5 pages)

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A cutaneous sinus tract or cutaneous fistula of dental origin occurs when purulent products of dental pulp necrosis spread along the path of least resistance from the root apex to the skin on the face. As many patients present with only skin problems and without toothache, it is frequently misdiagnosed as a cyst, abscess, pyogenic granuloma, actinomycosis, squamous cell carcinomas, and so on. Incorrect diagnoses lead to invasive procedures and long-term antibiotic therapy. We present 2 cases of recurrent suppurative facial dimpled nodules. Both of the cases were referred to the maxillofacial department, where the non-restorable teeth were extracted, and root canal therapy was performed. Lesions may persist for long periods before the correct diagnosis is made and the odontogenic source is treated appropriately. With early correct diagnosis, patients can be protected from unnecessary and ineffective antibiotic therapy or surgical treatment. Herein, we report 2 cases of a cutaneous sinus tract of dental origin. (Korean J Dermatol 2019;57(10):621∼625)

KCI등재 SCOPUS

8A Case of Angiomatoid Spitz Nevus with High Cellularity and Lymphovascular Tumor Emboli-like Features

저자 : Gi Hyun Seong , Uri Shon , Myeong Jin Park , Byung Cheol Park , Myung Hwa Kim , Seung Phil Hong

발행기관 : 대한피부과학회 간행물 : 대한피부과학회지 57권 10호 발행 연도 : 2019 페이지 : pp. 626-628 (3 pages)

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A Spitz nevus is an uncommon benign tumor that often occurs in children. Angiomatoid Spitz nevus is a rare and distinct variant of the Spitz nevus that exhibits a spindle and/or epithelioid nevus between angioma-like, densely arranged small blood vessels. We present a case of angiomatoid Spitz nevus with high cellularity and lymphovascular tumor emboli-like features. In our case, tumor cells with high cellularity were observed throughout the lesion, and lymphovascular tumor emboli-like nests were present. (Korean J Dermatol 2019;57(10):626∼628)

KCI등재 SCOPUS

9A Skin Metastasis from a Gastric Signet-Ring Cell Carcinoma in an Adolescent that Mimicked Steatocystoma Multiplex

저자 : Myoung Eun Choi , Woo Jin Lee , Sung Eun Chang , Mi Woo Lee , Jee Ho Choi , Seung Hwan Paik

발행기관 : 대한피부과학회 간행물 : 대한피부과학회지 57권 10호 발행 연도 : 2019 페이지 : pp. 629-631 (3 pages)

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Cutaneous metastases of internal malignancies are relatively rare and originate most frequently from tumors of the breast and lung. Herein, we present an unusual clinical presentation of a skin metastasis from a gastric signet-ring cell carcinoma in an adolescent. A 19-year-old boy presented with asymptomatic subcutaneous nodules on his abdomen and back. Histopathological examination revealed signet-ring cells with cytoplasmic mucin in the dermis. A diagnosis of cutaneous metastasis of a signet-ring cell carcinoma was made and the patient died 12 days after his initial visit to our dermatology clinic. Gastric carcinomas have infrequently been reported in adolescents, and cutaneous metastases from carcinomas in this group are extremely rare. Clinicians should be aware that skin metastases of adolescent gastric carcinoma can be similar in presentation to steatocystoma multiplex and that a skin biopsy is necessary for suspicious skin lesions. (Korean J Dermatol 2019;57(10):629∼631)

KCI등재 SCOPUS

10Coincidence of Dermal Melanocyte Hamartoma and Becker's Nevus in a Patient with Neurofibromatosis Type 1

저자 : Young Jae Kim , Myoung Eun Choi , Mi Woo Lee , Jee Ho Choi , Sung Eun Chang

발행기관 : 대한피부과학회 간행물 : 대한피부과학회지 57권 10호 발행 연도 : 2019 페이지 : pp. 632-634 (3 pages)

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Dermal melanocytosis is characterized by an increased number of ovoid to elongated melanocytes situated between collagen fibers in the dermis, including blue nevus, Mongolian spots, nevus of Ota and Ito and dermal melanocyte hamartoma. Herein, we present a rare case of a 15-year-old boy presented with both dermal melanocyte hamartoma and Becker's nevus in conjunction with neurofibromatosis. A shared pathophysiologic mechanism between neurofibromatosis and other nevi in the context of organoid hamartoma has been reviewed. (Korean J Dermatol 2019;57(10):632∼634)

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